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The aim of this study was to explore the potential misclassification and evaluate the completeness of esophageal cancer diagnoses in the FCR and HILMO, considering misclassification. Read the paper at https://www.tandfonline.com/doi/full/10.1080/0284186X.2020.1792547
The term of overadjustment bias is used to refer to different scenarios. Here, we propose a unified definition of overadjustment, with four types. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/Revisiting_Overadju…
https://www.lupop.lu.se/article/revisiting-overadjustment-bias - 2025-12-07
General population-based cohort studies provide solid evidence on mass Helicobacter pylori (HP) eradication effects. Self-reported questionnaires are occasionally used in such studies to ascertain the HP eradication history. However, reports on the reliability of these questionnaires are lacking. Read the paper at https://www.nature.com/articles/s41598-021-95124-1
Forskningsrådet Formas lanserar en ny satsning på forskning för en giftfri miljö, specifikt till projekt som kan öka kunskapen kring kombinationseffekter av kemikalier och substanser. Läs mer här.
https://www.lupop.lu.se/article/giftfri-miljo-i-fokus-ny-forskningssatsning - 2025-12-07
A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare utilization patterns. Read the paper at https://bmchealth
This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018
The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical environment. Read the paper at https://academic.oup.com/bjs
https://www.lupop.lu.se/article/future-surgical-registries - 2025-12-07
Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706
1) We found 15 national/regional registries of congenital heart disease worldwide. 2) Registry coverage ranged from 25 to 100% of all eligible cases. 3) The best registries contain demographic, clinical, physical, and laboratory data. 4) Regular verification is essential for quality data and valid statistical findings. Read the paper at https://www.sciencedirect.com/science/article/pii/S0167527321
We reweighted the Malmö Diet and Cancer (MDC) study based on population register data on background variables, including socio-demographics and hospital admissions for both participants and the background population. Following individuals from baseline in 1991-1996 and at most until 2016, we studied mortality (all-cause, cancer, and CVD), incidences (cancer and CVD), and associations between these
A project jointly conducted by the Nordic national statistical institutes and funded by NordForsk was initiated in 2015. The project, Nordic Microdata Access Network (NordMAN), seeks to establish a single pan-Nordic solution to facilitate researchers' access to the Nordic metadata compiled for statistical purposes, and to provide an overview of the existing Nordic registers. The project’s common N
Data from population-based cancer registries are often used to compare cancer survival between countries or regions. The ICBP SURVMARK-2 study is an international partnership aiming to quantify and explore the reasons behind survival differences across high-income countries. However, the magnitude and relevance of differences in cancer survival between countries have been questioned, as it is argu
We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. We used the Swedish Population Register to include all persons resident in the Skåne region in 2008 and asses
Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, without underlying structural
Participants are members of the Maccabi Health Services, 40–65 years of age, with exquisitely detailed laboratory, medical diagnoses and medication data available in the Maccabi electronic medical records since 1998. Data collected through IRAP include genetic, sociodemographic, cognitive, brain imaging, lifestyle, and health-related characteristics at baseline and every three years thereafter. Re
https://www.lupop.lu.se/article/israel-registry-alzheimers-prevention-irap-study-design-and-baseline-characteristics - 2025-12-07
Large prospective cohort studies may offer an opportunity to study the etiology and natural history of rare cancers. Cancer diagnoses in observational cohort studies are often self-reported. Little information exists on the validity of self-reported cancer diagnosis, especially rare cancers, in Canada. This study evaluated the validity of self-reported cancer diagnosis in Alberta’s Tomorrow Projec
https://www.lupop.lu.se/article/importance-cancer-registry-linkage-studying-rare-cancers-prospective-cohorts - 2025-12-07
Acquisition of data on clinical performance is essential to improve outcomes in surgery. Large, national datasets allow hospitals to monitor events involving patient safety, complications, and benchmark against peer hospitals and facilitate quality improvement (QI) development. Although clinical datasets are often preferable, administrative data also have potential for actionable QI. Hospitals sho
https://www.lupop.lu.se/article/administrative-and-registry-databases-patient-safety-tracking-and-quality-improvement - 2025-12-07
A nationwide random sample of 500 children (6–17 years) diagnosed with depression between 1996 and 2016 was identified in the DPCRR. Psychiatric hospital records were reviewed and rated using an online checklist. The primary outcome was whether depressive symptoms and functional impairment documented in hospital records justified a depressive disorder diagnosis based on ICD‐10 or DSM‐5 diagnostic
A cross sectional study was piloted at a tertiary hospital and a secondary level hospital in Botswana. The study consisted of two stages: stage 1 - stakeholders' consultation and trauma registry prototype was designed. Stage 2 consisted of two phases: Phase I involved retrospective collection of existing data from existing data collection tools and Phase II collected data prospectively using the p
https://www.lupop.lu.se/article/developing-trauma-registry-middle-income-country-botswana - 2025-12-07
A nationwide random sample of 500 children (6–17 years) diagnosed with depression between 1996 and 2016 was identified in the DPCRR. Psychiatric hospital records were reviewed and rated using an online checklist. The primary outcome was whether depressive symptoms and functional impairment documented in hospital records justified a depressive disorder diagnosis based on ICD‐10 or DSM‐5 diagnostic
