Published 1 July 2020 The implementation of screening programmes in Sweden during the mid‐1990s increased the number of small node‐negative breast cancers. In this era before staging by sentinel node biopsy, routine axillary dissection for staging of early breast cancer was questioned owing to the increased morbidity and lack of perceived benefit. The long‐term risk of axillary recurrence when axi

https://www.lupop.lu.se/article/long-term-outcome-pt1a-b-cn0-breast-cancer-without-axillary-dissection-or-staging-prospective - 2025-05-15

Published 1 July 2020 As information and communication technology has become pervasive in our society, we are increasingly dependent on both digital data and repositories that provide access to and enable the use of such resources. Repositories must earn the trust of the communities they intend to serve and demonstrate that they are reliable and capable of appropriately managing the data they hold

https://www.lupop.lu.se/article/trust-principles-digital-repositories - 2025-05-15

Published 2 July 2020 The increasing trends in cesarean delivery are globally acknowledged. However, in many low-resource countries, socioeconomic disparities have created a pattern of underuse and overuse among lower and higher socioeconomic groups. The impact of rising cesarean delivery rates on neonatal survival is also unclear. New publication in Global Health Action

https://www.lupop.lu.se/article/cesarean-delivery-and-associated-socioeconomic-factors-and-neonatal-survival-outcome-kenya-and - 2025-05-15

Published 2 July 2020 Although it has been established that low socioeconomic status is linked to increased risk of death after stroke, the mechanisms behind this link are still unclear. In this study we aim to shed light on the relationship between income level and survival after stroke by investigating the extent to which differences in stroke severity account for differences in survival. New pu

https://www.lupop.lu.se/article/socioeconomic-status-and-survival-after-stroke-using-mediation-and-sensitivity-analyses-assess-0 - 2025-05-15

Published 10 June 2020 På SND:s hemsida lanseras nu nya sidor om datahantering riktade till forskare. Materialet som tagits fram är tänkt att ge en överblick över datahantering i forskningsprojekt och erbjuda stöd genom hela forskningsprocessen, från planeringsstadiet till projektslut. Läs mer på https://snd.gu.se/sv/nyheter/snd-lanserar-nya-sidor-om-datahantering-fo….

https://www.lupop.lu.se/article/snd-lanserar-nya-sidor-om-datahantering-forskare - 2025-05-15

Published 3 July 2020 While acute dizziness often is associated with vestibular deficits or of central nervous system (CNS) origin, the etiology of longstanding complaints of dizziness often cannot sufficiently be explained by such pathology alone. When vestibular deficits remain, the CNS is often able to compensate for the reduced or asymmetric vestibular activity with other sensory input, such a

https://www.lupop.lu.se/article/dizziness-and-localized-pain-are-often-concurrent-patients-balance-or-psychological-disorders - 2025-05-15

Published 3 July 2020 Across today’s developed world, there is a clear mortality gradient by socioeconomic status for all ages. It is often taken for granted that this gradient was as strong—or even stronger—in the past when social transfers were rudimentary and health care systems were less developed. Some studies based on cross-sectional data have supported this view, but others based on longitu

https://www.lupop.lu.se/article/when-did-health-gradient-emerge-social-class-and-adult-mortality-southern-sweden-1813-2015 - 2025-05-15

Published 4 July 2020 Preterm birth has been associated with elevated blood pressure early in life; however, hypertension risks from childhood into adulthood remain unclear. We conducted a large population-based study to examine gestational age at birth in relation to hypertension risks from childhood into adulthood. New publication in European Heart Journal

https://www.lupop.lu.se/article/risk-hypertension-adulthood-persons-born-prematurely-national-cohort-study - 2025-05-15

Published 4 July 2020 Patients with an emergency admission for diverticular disease to any Norwegian hospital between 1 January 2008 and 31 December 2010 were included through identification in the Norwegian Patient Registry using International Classification of Diseases (ICD‐10) codes K57.1‐9. To estimate the age‐specific distribution of CT‐verified acute uncomplicated diverticulitis (AUD) and ac

https://www.lupop.lu.se/article/risk-colorectal-cancer-following-ct-verified-acute-diverticulitis-nationwide-population-based-cohort - 2025-05-15

Published 5 July 2020 The use of patient‐reported outcome (PRO) measured outside clinical trials is not well defined. We report the first analysis of the prospective PRO study within the Swedish acute myeloid leukemia (AML) and the acute lymphoblastic leukemia (ALL) registries. New publication in European Journal of Haematology

https://www.lupop.lu.se/article/introducing-patient-reported-outcome-acute-leukemia-quality-registries-sweden - 2025-05-15

Published 5 July 2020 The number of children who were born after their parents were diagnosed with central nervous system (CNS) tumor is increasing, but it remains largely unknown regarding the academic performance of these children. We aimed to investigate whether children of survivors with childhood or adolescent CNS tumor were associated with poor academic performance. Children of survivors of

https://www.lupop.lu.se/article/poor-academic-performance-offspring-survivors-childhood-or-adolescent-central-nervous-system-tumor - 2025-05-15

Published 6 July 2020 We seek to identify factors that facilitate or inhibit transmission of drug abuse (DA) from high-risk parents to their children. In 44,250 offspring of these parents, ascertained from a Swedish national sample for having a mother and/or father with DA, we explored, using Cox models, how the prevalence of DA was predicted by potentially malleable risk factors in these high-ris

https://www.lupop.lu.se/article/facilitating-versus-inhibiting-transmission-drug-abuse-high-risk-parents-their-children-swedish - 2025-05-15

Published 6 July 2020 We introduce and apply an elegant, contrastive genetic-epidemiological design – Maternal Half-Sibling Families with Discordant Fathers – to clarify cross-generational transmission of genetic risk to alcohol use disorder (AUD), drug abuse (DA) and major depression (MD). New publication in Psychological Medicine

https://www.lupop.lu.se/article/maternal-half-sibling-families-discordant-fathers-contrastive-design-assessing-cross-generational - 2025-05-15

Published 7 July 2020 Perfluoroalkyl substances (PFASs) are widespread, bioaccumulating, and persistent and show placental transfer. Emerging research indicates associations between prenatal exposure and low birth weight. The aim of this study was to assess the associations between first trimester exposure to PFASs and birth weight (BW) in the Swedish Environmental, Longitudinal, Mother and child,

https://www.lupop.lu.se/article/maternal-serum-levels-perfluoroalkyl-substances-early-pregnancy-and-offspring-birth-weight - 2025-05-15

Published 7 July 2020 Elderly patients with acute myocardial infarction undergoing percutaneous coronary intervention are at increased risk of both ischemic and bleeding complications. The optimal anticoagulation strategy in these patients is uncertain. Therefore, we compared bivalirudin to heparin monotherapy in a contemporary cohort of such patients. New publication in Circulation: Cardiovascula

https://www.lupop.lu.se/article/bivalirudin-versus-heparin-monotherapy-elderly-patients-myocardial-infarction-prespecified-subgroup - 2025-05-15

Published 8 July 2020 Incidence of ST-elevation myocardial infarction (STEMI) is increasing in Nepal. We aim to describe the presentation, management, complications, and outcomes of patients admitted with a diagnosis of STEMI in Shahid Gangalal National Heart Centre (SGNHC), Nepal. New publication in Nepalese Heart Journal

https://www.lupop.lu.se/article/shahid-gangalal-national-heart-centre-st-elevation-myocardial-infarction-registry-sgnhc-stemi - 2025-05-15

Published 8 July 2020 There has been considerable interest in recent years in quantifying the rate of unavoidable or so‐called random cancers, as opposed to cancers linked to environmental, genetic or other factors. We propose a data‐based approach to estimate an upper limit to this probability, based on an analysis of multiple registry data. The argument is that the cumulative hazards for random

https://www.lupop.lu.se/article/random-cancers-supported-registry-data - 2025-05-15

Published 9 July 2020 Deidentified data from the Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4) and the ACPR were linked. Children born from 1996 to 2000 at Australian hospitals who survived and had 2‐year paediatric assessments were included. Children identified with CP in: (1) both the ACTOMgSO4 (2y) and the ACPR (5y), (2) the ACTOMgSO4 only, and (3) the ACPR only were compar

https://www.lupop.lu.se/article/linking-data-large-clinical-trial-australian-cerebral-palsy-register - 2025-05-15

Published 9 July 2020 The aims were to investigate the association between maternal serum levels of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS) and perfluorononanoic acid (PFNA) in early pregnancy and overweight in the child at 4 years and to assess potential heterogeneity in exposure effect between strata with different levels of other risk f

https://www.lupop.lu.se/article/intrauterine-exposure-perfluorinated-compounds-and-overweight-age-4-case-control-study - 2025-05-15

Published 10 July 2020 Population-based administrative registers are often used for research purposes. However, their potential usefulness depends on the validity of the registered information. This study assessed the validity of the recorded codes for social anxiety disorder (SAD), also known as social phobia, in the Swedish National Patient Register (NPR). New publication in BMC Psychiatry

https://www.lupop.lu.se/article/validity-and-reliability-social-anxiety-disorder-diagnoses-swedish-national-patient-register - 2025-05-15