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Many preterm infants are exposed to multiple transfusion types during their admission in the neonatal intensive care unit. Yet, evidence supporting current practice consists of several randomized controlled trials and observational studies focusing on a single transfusion product at the time. Rather than approaching transfusions as three distinct categories as currently done in the literature, the
Objective: To describe the normal heart rate (HR) of healthy newborns ≥35+0 weeks’ gestation in the first 10 min after caesarean delivery (CD) with extrauterine placental transfusion, using dry-electrode ECG (NeoBeat). Design: Single-centre, prospective observational study. Setting: Norwegian County Hospital. Patients: Newborns ≥35+0 weeks’ gestation delivered by CD under regional anaesthesia were
This article presents a new way of obtaining deep explanations of environmental problems. We expose the production strategies, corporate strategies and state actions that have been taken by firms and state agencies to facilitate the geographical expansion of the wood-based commodity frontier at the expense of reindeer pastoralists among the Indigenous Sámi people. Through qualitative analysis of a
Circular economy (CE) policy has largely developed around product markets, where ecodesign, repairability requirements, and extended producer responsibility now form a substantial regulatory layer. In regulated energy infrastructure, where replacement decisions are shaped by depreciation schedules, regulatory review cycles, and procurement rules, these tools have made limited progress. This perspe
Ventricular function is vital in patients with single ventricles but repeated surgeries and changes in ventricular volume load may change the relation between longitudinal and radial function. To expand the knowledge of cardiac mechanics in this population, the aim of this study was to assess longitudinal and radial contribution to stroke volume using cardiac magnetic resonance (CMR) imaging in pa
Aims: 4D blood flow measurements by cardiac magnetic resonance imaging (CMR) can be used to simplify blood flow assessment. Compressed sensing (CS) can provide better flow measurements than conventional parallel imaging (PI), but clinical validation is needed. This study aimed to validate stroke volume (SV) measurements by 4D-CS in healthy volunteers and patients while also investigating the influ
Water hyacinth is among the world’s most damaging aquatic invasive plants, forming dense mats that disrupt ecosystem functioning, fisheries, navigation, and livelihoods across tropical and subtropical freshwater systems. Its rapid spread is driven by clonal propagation, short life cycles, and prolific seed production, particularly under nutrient-enriched conditions. Although mechanical, chemical,
Climate change and escalating human pressures erode the resilience of global forests, putting biodiversity, carbon storage, and societal well-being at risk. Fragmented, single-sector responses cannot keep pace with the speed or complexity of these threats. By synthesizing insights from resilience theory and global practices across ecological, social, and institutional dimensions, we propose 10 mut
The urgency of addressing climate change has underscored the need for precise carbon management—an approach that precisely monitors, assesses, and manages carbon emissions and sequestration at fine spatial, temporal, and sectoral scales. This perspective paper examines the current state of precise carbon management, highlighting advancements in ground-based observations, remote sensing, process-ba
Tropical rainforests have complex responses to seasonal climatic variations. Compared to the Amazon and Asian rainforests, the Congo rainforest exhibits a more widespread bimodal seasonal pattern, yet it remains understudied. Here, we use three independent satellite-based vegetation indices to investigate the seasonal variations of the Congo rainforest, including solar-induced chlorophyll fluoresc
Photoionization of atoms by high-order harmonics in the presence of a laser may lead to quantum interference from which information about the photoionization dynamics or the light fields can be extracted. Traditionally, this interference arises from two-photon transitions involving the absorption of consecutive harmonics combined with the absorption and stimulated emission of a laser photon. In th
Metastable cubic tin(II) sulfide (π-SnS) is an earth-abundant semiconductor whose three-dimensionally bonded chiral lattice may overcome the short minority-carrier lifetime of orthorhombic SnS while maintaining a near-ideal bandgap for tandem photovoltaics. Despite its promise, ultrafast carrier cooling and recombination mechanisms over illumination density remain poorly constrained. We use core-l
Consanguineous marriage is prevalent in certain world regions due to cultural, economic, and social reasons. However, it can lead to negative consequences including an increased risk of genetic disorders in offspring. Premarital genetic screening (PMGS) is an important tool to identify and manage these risks before marriage. This study aimed to assess the magnitude of consanguineous marriage, know
Hereditary spinocerebellar degenerations (SCDs) is an umbrella term that covers a group of monogenic conditions that share common pathogenic mechanisms and include hereditary spastic paraplegia (HSP), cerebellar ataxia, and spinocerebellar ataxia. They are often complicated with axonal neuropathy and/or intellectual impairment and overlap with many neurological conditions, including neurodevelopme
ATPase, class 1, type 8 A, member 2 (ATP8A2) is a P4-ATPase with a critical role in phospholipid translocation across the plasma membrane. Pathogenic variants in ATP8A2 are known to cause cerebellar ataxia, impaired intellectual development, and disequilibrium syndrome 4 (CAMRQ4) which is often associated with encephalopathy, global developmental delay, and severe motor deficits. Here, we present
Heterozygous PRRT2 variants are frequently implicated in Self-limited Infantile Epilepsy, whereas homozygous variants are so far linked to severe presentations including developmental and epileptic encephalopathy, movement disorders, and intellectual disability. In a study aiming to explore the genetics of epilepsy in the Sudanese population, we investigated several families including a consanguin
Importance: Early identification of the likelihood of autism spectrum disorder (ASD) using minimal information is crucial for early diagnosis and intervention, which can affect developmental outcomes. Objective: To develop and validate a machine learning (ML) model for predicting ASD using a minimal set of features from background and medical information and to evaluate the predictors and the util
Developmental language disorder (DLD) overlaps clinically, genetically, and pathologically with other neurodevelopmental disorders (NDD), corroborating the concept of the NDD continuum. There is a lack of studies to understand the whole genetic spectrum in individuals with DLD. Previously, we recruited 61 probands with severe DLD from 59 families and examined 59 of them and their families using mi
Machado-Joseph disease (MJD/SCA3) is the most frequent dominant ataxia worldwide. It is caused by a (CAG)n expansion. MJD has two major ancestral backgrounds: the Machado lineage, found mainly in Portuguese families; and the Joseph lineage, present in all five continents, probably originating in Asia. MJD has been described in a few African and African-American families, but here we report the fir
Autosomal dominant cerebellar ataxia (ADCA) accounts for more than fifty inherited neurological diseases caused by various underlying mechanisms leading to progressive or intermittent phenotypes. Most ADCAs develop due to alterations in signal transduction, ion homeostasis, or pathological DNA expansions. Yet, other pathological mechanisms can directly or indirectly contribute to the development o
