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We extend the generalized information criteria framework for model selection to high-dimensional sparse statistical jump models, a recent class of statistically robust and computationally efficient alternatives to hidden Markov models. Specifically, we derive expressions for the model fit and complexity to construct suitable information criteria for hyperparameter selection. In extensive simulatio
Governance of sustainable development increasingly relies on voluntary standards and commitments, the credibility and effectiveness of which hinge on accountability—ensuring actors align with shared goals and follow through on them. However, voluntary initiatives operate outside traditional control structures and blend elements of state, market, and community governance. This study examines how ac
The growing passion for indoor optical wireless networks reflects their immense capability to deliver consistent high-quality data connectivity across diverse indoor environments. This study examines how polarization can be engineered to enhance near-field beam focusing in optical wireless indoor networks using a modular clustered optical phased array aperture. The aperture follows a ceiling-mount
Quantitative epidemiological studies have identified victim- or fire-related risk factors for fire mortality and have shown radical sociodemographic differences. Whilst important, such studies are limited in explaining the underlying reasons why some individuals are more vulnerable than others. Based on focus group interviews with nurses at burn clinics in Sweden, this qualitative study therefore
Direct catalytic conversion of methane to methanol offers a pathway for transforming a potent greenhouse gas into a portable clean liquid fuel, thereby mitigating carbon emissions and supporting sustainable energy. However, this process faces challenges from thermodynamically favorable methanol overoxidation. Here, we show that spatiotemporal regulation of photogenerated charge carriers on enginee
Conventional femtosecond coherent laser spectroscopy predominantly focuses on the temporal phase coherence through time- or frequency-resolved methods. In this Letter, we suggest an alternative experimental framework based on spatial phase coherence. The intrinsic spectral dispersion of wave vectors in femtosecond pulses and sample dimensions exceeding the laser wavelength creates a compelling bas
Purpose: IgG subclass genes from chromosome 14q32.3 are assessed serologically by GM allotypes, genetic markers of the Fc part of the immunoglobulin constant heavy G chains, (IGHG(Fcγ)(GM) genes. Alternative GM allotypes of IgG3, IgG1 and IgG2, respectively, define 6 unique, precise GM-specific IgG subclass genes, inherited the Mendelian way with allelic exclusion, and linkage disequilibrium of Ig
Abstract – Introduction: – Spinal disorders are among the biggest contributors to health care utilization (HCU).Objective: – To develop and externally validate a prediction model for high all-cause HCU (75th percentile during 1 year after the index date) among patients with spinal disorders visiting multidisciplinary secondary care clinics.Methods: – We developed and internally validated the model
In this paper, we propose the design of a roof-glass integrated microstrip antenna for vehicular SDARS tuners. The proposed microstrip antenna is sandwiched inside a multi-layer roof glass and uses a solar-heat reduction coating on the bottom side of the glass as ground plane. To offset the effect of the lossy glass, parasitic elements are added to enhance the antenna gain. Simulation results show
Background Postinfectious autoimmune processes are hypothesized to be causally implicated in tic disorders, including Tourette syndrome and chronic tic disorder. However, this hypothesis remains controversial. In this nationwide cohort study, we aimed to clarify the mechanisms underlying the association between proneness to infections and tic disorders. Methods Using Swedish national registers, we
A computational method to simulate bimolecular quenching reactions using coarse-grained reaction-diffusion dynamics is presented and applied to the quenching of molecular photosensitizers in solution. The simulations describe photoinduced reactions involving explicit excited states of light-harvesting species together with intrinsic deactivation, as well as collision quenching from separate quench
Although variations in temperature have a profound impact on cardiac function, little is known regarding the excitation and contractile parameters over a broad temperature interval. In view of the clinical implications of lowered temperature in resuscitation and in cardiac preservation/evaluation for transplantation, we have examined the contractile function using Langendorff perfused hearts and i
Background: Influenza infection increases the risk of pneumonia and respiratory failure in chronic obstructive pulmonary disease (COPD) and mucins play an important role in pulmonary host defense. Methods: Lower airway mucins were obtained from long-term smokers with and without COPD, pneumonia patients, and healthy never-smokers; oral MUC5B was obtained from a healthy never-smoker, and the abilit
The combined use of waste heat (WH), ground-source heat pumps (GSHPs), and district heating (DH) offers an effective pathway to decarbonize urban heating. Taking a system-integration perspective, this review synthesizes technical, operational, and policy dimensions of WH-assisted GSHPs coupled to DH. Both centralized and decentralized configurations are examined, focusing on thermal energy storage
Background: Isothiazolinones are widely used as preservatives in both cosmetic and non-cosmetic products. Sensitisation to isothiazolinones other than chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT), present in the baseline series, is increasing. Objectives: To investigate the prevalence of sensitisation to benzisothiazolinone (BIT) in comparison to CMIT/MIT and to develop a product-i
Recent research efforts highlight the challenges associated with accurately assessing the true magnitude of the energy performance gap in buildings. Uncertainties in both predictions and measurements raise questions about the extent of the gap, its implications, and whether it is narrowing or widening. Typically, the gap is quantified by comparing measured data with various energy benchmarks and t
Human babesiosis is an emerging disease as more cases are being reported worldwide. Most cases in Europe are caused by Babesia divergens, whereas most cases in North America are due to Babesia microti. While B. microti is also found throughout Europe, it appears to be less pathogenic. We generated high-quality nuclear and organellar genome assemblies of two B. divergens and two B. microti isolates
How we measure success in signal comprehension experiments fundamentally shapes our conclusions. Two recent studies have demonstrated that humans can guess the meanings of novel vocalizations and ape gestures above chance when selecting from limited alternatives. We replicated both experiments using open-ended responses instead of multiple choice. For the vocalization data, where participants prov
Cold acclimation is a crucial physiological process that enables plants to adapt to low temperatures. A key aspect of this acclimation is lipid remodeling, which preserves membrane fluidity and integrity under cold stress. Proteins of the chloroplast envelope membranes are increasingly recognized for their role in acclimation to changing environmental conditions. While lipid synthesis occurs at th
While sharing good teaching practice is at the core of most academic developers’ professional roles, little systematic evidence has been collected on this topic so far. This paper investigates if, how and for what specific purposes academic developers collect and share teaching artefacts. We report on an exploratory, survey-based study among academic developers from around the world. Our findings
