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A package material blank comprises a body panel having a main panel, two second panels arranged adjacent to the main panel and at least one third panel. End closure panels arranged adjacent to the body panel, the end closure panels comprising a top and bottom closure panels arranged adjacent to the main and the at least one third panel, respectively and flap closure panels arranged adjacent to the
Digital cognitive assessments have rapidly expanded in Alzheimer's disease (AD) research, offering a sensitive, scalable, and cost-effective alternative to traditional neuropsychological tests. This systematic review examines the validation and utility of digital cognitive assessments in cognitively normal (CN) individuals and explores their potential classification within the US Food and Drug Adm
Background: The purpose of this study was to analyse if there is a relationship between the directions of windswept hip deformity and scoliosis for children with cerebral palsy (CP) and to explore potential associations with spasticity, contractures and hip displacement. Methods: A cross-sectional registry-based study was conducted using data from the combined Swedish CP Follow-up Program and Nati
Syftet med uppsatsen är att bedöma användningen av EncroChat bevisning inför svensk rätt utifrån den naturrättsliga filosofen Andrew Dworkins teori om statlig integritet. Enligt Dworkin är det viktigt att stater konsekvent till-lämpar moraliska och rättsliga principer i deras rättssystem, då detta ger sta-ten en intern integritet som stärker tilliten mellan den enskilde och det all-männa. UppsatseThe purpose of the paper is to assess the use of EncroChat evidence before Swedish law based on the natural law philosopher Andrew Dworkin’s theo-ry of state integrity. According to Dworkin, it is important that states con-sistently apply moral and legal in their legal systems, as this gives the states an internal integrity that strengthens trust between the individual and the public. The paper ex
Rates of hybridization are increasing globally, but we lack an understanding of both the history and evolutionary outcomes of hybridization for most species. This makes it difficult to understand whether, and to what extent, humans are influencing hybridization. Integrating field studies with whole genome data is a critical next step for understanding hybridization and the extent of human influenc
The so-called X17 particle has been proposed in order to explain a very significant resonant behaviour (in both the angular separation and invariant mass) of e+e− pairs produced during a nuclear transition of excited 8Be, 4He and 12C nuclei. Fits to the corresponding data point, as most probable explanation, to a spin-1 object, which is protophobic and has a mass of approximately 16.7 MeV, which t
High-altitude regions are highly vulnerable to impacts of climate change because the retreat of glaciers and snow impacts ecosystems, local livelihoods, cultural practices, and values. Although glacier change is widely documented within the natural sciences, limited focus has been given to the lived experiences of emerging challenges in changing glacier environments. We used a mixed methods approa
Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies reporting the outcome after postcardiotomy VA-ECMO in adult patients were identified through a systematic review of the literature. Individual patient-level data were provided by t
Background: There are two conceptually different surgical treatment options for patients with T1 colorectal cancer (CRC): radical surgical resection and local resection. In addition, adjuvant chemotherapy is recommended in cases with lymph node metastases. However, surgical overtreatment of early CRC is a concern and may be related to limitations in preoperative work-up as well as tumour risk clas
Background: White adipose tissue (WAT) dysfunction including an aberrant expression of miRNAs is strongly associated with the risk of developing type 2 diabetes (T2D), with limited evidence linking early changes in the WAT-derived miRNAs and T2D. The present study aims to identify early miRNome changes prognostic for T2D in mice and humans. Methods: Gonadal (g) WAT of diabetes-resistant and diabet
In healthcare, the ability to make sense of data is crucial for informed and responsible decision-making. However, the ongoing digitalization of healthcare and its reliance on heterogeneous forms of data has made sensemaking increasingly complex. Data is generated, presented, and used through a variety of tools, practices, and algorithmic systems, and its meaning demands careful and context-sensit
The recent COVID-19 pandemic has considerably impacted negatively on many aspects of human life such as access to basic necessities including water, energy and food. This article aims to investigate the impact of the COVID-19 lockdown on the water, energy and food accessibility in Katsina state, Nigeria. The survey involved the administration of a questionnaire to a total of 900 households out of
We present a quantum repeater protocol for distributing entanglement over long distances, where a dedicated communication stage enables trial rates not limited by the travel time between repeater nodes. To accomplish this, each node contains several qubits that can couple to one single-photon emitter. Photons from the emitters in neighboring nodes generate heralded entanglement between qubits in t
Maritime networks have been proposed as a mechanism for early agricultural and, by extension, language dispersals in several coastal and island regions. In Island Southeast Asia, such networks have sometimes been discussed as an alternative to the farming/language dispersal hypothesis. However, the relationships between Neolithic maritime networks and maritime economies are poorly known. Here, we
BACKGROUND Surgical site infection (SSI) following orthopedic surgery impacts patient outcomes. Airborne transmission is one potential route of infection. Despite their high cost and resource demands, modern ventilation systems have shown limited efficacy in reducing SSI rates. This trial investigated the effectiveness of a low-cost air purifier in reducing SSI rates after orthopedic surgery. METH
African Swine Fever (ASF) has been posing a significant threat to pig production and wildlife management in the Republic of Serbia since its first detection in 2019. The goal of this study is to provide a comprehensive overview of the spatial and temporal spread of ASF in both domestic and wild pig populations in Serbia from the initial outbreak in the summer of 2019 through May 2025. Additionally
Abstract – Introduction: Peripheral intravenous catheterization is commonly required in sick neonates but remains challenging due to small vessels, leading to multiple attempts and complications. This review evaluated the benefits and harms of device-assisted techniques versus standard technique. Methods: We searched MEDLINE, Embase, CENTRAL, Cochrane Reviews, WHO ICTRP, and ClinicalTrials.gov (Oc
Purpose: – To validate the Catquest-9SF survey in a US Veteran population while assessing how cataract surgery impacts quality of life from the patient’s perspective.Setting: – Edward Hines Jr. VA Hospital. Hines, IL, USA.Design: – A prospective survey study of Veteran patients undergoing cataract surgery, gauging pre- and post-operative responses to questions regarding vision-related daily tasks.
The 1st Ecuadorian Dendrochronology Conference (ECUADENDRO 2025) took place in Daule, Ecuador, on January 23–24, 2025, with the generous sponsorship of the Tree-Ring Society. The event attracted 230 participants from 45 countries, bringing together leading experts in various subfields of tree-ring science, including dendroclimatology, dendroecology, dendrogeomorphology, dendroarchaeology, and cell
