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Introduction: Excessive worry is common during adolescence and across a range of psychiatric conditions. There is a growing evidence base for the efficacy of cognitive behaviour therapy (CBT) in reducing the frequency of excessive worrying as a primary outcome in the context of clinical trials of youth with generalized anxiety disorder, and as a secondary outcome in trials of CBT for youth with ob

Documented performance featuring spherical amplification.Acht BrückenKölner Philharmonie, Cologne (DE)Ensemble Musikfabrik05/05/2024Program:Poppe, Enno (*1969, DE) – Prozession (for large ensemble) [2015/2020]

Damage, failures, and defects in buildings create an enormous cost for stakeholders. This study examined technical aspects of inadequate management and maintenance causing moisture and indoor environment related damage instances. Using a dataset of 2100 diagnosed causes of damage based on real damage investigations carried out in Sweden, several of the factors causing damage were identified. The c

Amelogenin, the most abundant protein in developing enamel, self-assembles into supramolecular structures that serve as templates for apatite growth. Recent studies revealed that amelogenin nanoribbons exhibit hallmark features of functional amyloids, yet the molecular mechanisms governing their formation remain incompletely understood. Here, we combine atomic force microscopy, transmission electr

Background Bariatric metabolic surgery (Roux-en-Y gastric bypass [RYGB] and sleeve gastrectomy [SG]) effectively treats obesity and type 2 diabetes; however, weight loss varies, necessitating predictive factors. Methods We analysed 12- and 24-month weight loss data from 811 patients (RYGB or SG). Factor Analysis of Mixed Data and neural network (NN) modelling identified distinct patient phenotypes

This dissertation examines the construction of monumental synagogues in nineteenth-century Sweden as a means through which Jewish communities articulated public presence, negotiated belonging, and translated aspirations for civic inclusion into durable architectural form. Focusing on five purpose-built synagogues in Gothenburg (1855), Norrköping (1858), Stockholm (1870), Karlstad (1899), and Malmö

Oats ( Avena sativa ) are commonly kilned to inactivate native lipases, yet the impact of kilning on the storability of oats is not fully understood. In this study the impact of kilning on five different oat varieties during 12 months of continuous storage was investigated. The study included three commercial oat varieties with different lipid contents, and two novel oat lines selected for decreas

Developing radiation tumor biomarkers that can guide personalized radiotherapy clinical decision making is a critical goal in the effort towards precision cancer medicine. High-throughput molecular assays paired with modern computational techniques have the potential to identify individual tumor-specific signatures and create tools that can help understand heterogenous patient outcomes in response

This study presents a simulation-based framework for evaluating energy renovation strategies across European building typologies and climate zones. A factorial parametric approach was used to simulate over 800,000 combinations of envelope assemblies, HVAC systems, and shading controls for three archetypes (single-family, multi-family, office) across five European climate zones under both current a

BACKGROUND: The isolation of cell-free DNA (cfDNA) from the bloodstream can be used to detect and analyze somatic alterations in circulating tumor DNA (ctDNA), and multiple cfDNA-targeted sequencing panels are now commercially available for Food and Drug Administration (FDA)-approved biomarker indications to guide treatment. More recently, cfDNA fragmentation patterns have emerged as a tool to inf

The International Agency for Research on Cancer has recently classified occupational exposure as a firefighter as carcinogenic (group 1A). Even though the occupation of firefighter is associated with high exposure to pollutants, it is challenging to carry out exposure studies to assess health risks due to the extreme conditions associated with firefighting. Routine monitoring of occupational expos

In collisions between heavy nuclei, such as those at the Large Hadron Collider (LHC) at CERN, hydrodynamic models have successfully related measured azimuthal momentum anisotropies to the transverse shape of the collision region. For an elliptically shaped interaction area, the hydrodynamic pressure gradient is greater along the minor axis, resulting in increased particle momentum in that directio

Coastal port cities are key regions for carbon emissions (CEs) research in China, due to their industrial density, frequent transportation, and diverse human activities. Taking Ningbo City as a case study, this study employed a top-down accounting method and integrated multiple sources of geospatial data to reveal the spatiotemporal distribution characteristics of CEs from four sectors, including

The building sector is the largest contributor to greenhouse gas (GHG) emissions, primarily due to two factors: the embodied energy of construction materials and the operational energy consumed over a building’s lifespan. Given this substantial environmental impact, sustainability and climate resilience have become critical priorities in global policy frameworks. Addressing this challenge requires

The aim of this project is to discuss how designers can contribute to gender equality and female empowerment in craft-production industry. The study was done as a collaboration with the Indian organization Industree to study methods designers can use to assure that the economic/social balance in the value chain is fair. The organization works with craft-production as a means of generating income a

Widespread vegetation changes have been evidenced by satellite-observed long-term trends over decades in vegetation indices (VIs). However, many issues can affect the derived VIs trends, among which the inherent difference between VIs calculated from the same input reflectance has not been investigated. Here, we compared global long-term trends in six widely used RED-NIR (near-infrared)-based VIs

Background: Low-molecular-weight heparin (LMWH) is recommended for thromboprophylaxis in adult intensive care unit (ICU) patients. Despite its widespread use, there is insufficient evidence on the optimal dose, and there appears to be practice variation. Determining the LMWH dosing strategy that most effectively balances the risks of venous thromboembolism (VTE) and bleeding may improve outcomes i

Introduction: Preclinical studies have demonstrated the ability of FLASH irradiation to expand the therapeutic window by sparing normal tissues. The heart is a critical organ at risk in patients receiving radiotherapy for thoracic cancers. This study aimed to quantify the cardiac sparing effects of photon FLASH delivered as single (FLASH) or FLASH split dose (FSD) exposures. Methods: Female C57BL/