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Background: To compare echocardiographic and cardiac magnetic resonance imaging (CMR) measurements of global longitudinal strain (GLS) and global mitral annular plane displacement in women with breast cancer undergoing chemotherapy. The study focused on assessing the mitral annular plane systolic excursion (MAPSE) in echocardiography (ECHO) and atrioventricular plane displacement (AVPD) in CMR as
BACKGROUND: The evidence linking sugar intake to cardiovascular disease risk remains largely inconclusive, with variations observed across different subgroups of sugar intake. In addition, studies on genetic markers of sugar intake are scarce, especially for different sugar subgroups.OBJECTIVE: This genome-wide association study (GWAS) aimed to investigate genetic variants associated with the inta
Measurements of the Higgs boson production times decay rates and differential cross-sections have recently been performed by the ATLAS experiment in several decay channels using up to 139 fb−1 of proton-proton collision data at s = 13 TeV recorded at the Large Hadron Collider. This paper presents multiple interpretations of these Higgs boson measurements. Measurements of production-mode cross-sect
A search for neutral long-lived particles (LLPs) decaying in the ATLAS hadronic calorimeter using 140 fb−1 of proton-proton collisions at s = 13 TeV delivered by the LHC is presented. The analysis is composed of three channels. The first targets pair-produced LLPs, where at least one LLP is produced with sufficiently low boost that its decay products can be resolved as separate jets. The second an
The inclusive cross section for the production of a single top quark in association with a Formula Presented boson is measured using Formula Presented of proton-proton collision data collected with the ATLAS detector at Formula Presented. Events containing two charged leptons and at least one jet identified as originating from a Formula Presented-quark are selected. A multivariate discriminant is
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a
Helsingborg has a strong trading heritage and a unique strategic location within the Nordic region. It's no coincidence that these factors have combined in the digital age to position Helsingborg as a key player in the world of e-commerce.The city's natural geographic advantages, alongside significant investments in infrastructure, have established a strong foundation for Helsingborg to become a l
The Viking Age (c. 800 – c. 1050 AD) was a period of dramatic change and transformative encounters across Europe and the wider world. Ships, seafarers, and the sea were central to these developments but, paradoxically, the Viking Age is generally studied through evidence and approaches on land. This has consistently hindered scholarly understanding of the maritime dimensions of the Viking Age; sur
The South African forestry supply chain is a complex system that involves both the production of trees (site preparation, re-establishment, tending, and maintenance operations) and the production and distribution of wood products from plantation stands to the pulp- and sawmills. This paper reports on a study that investigated the suitability of discrete-event simulation for modelling forestry supp
The majority of soil carbon (C) is stored in organic matter associated with reactive minerals. These mineral-organic associations (MOAs) inhibit microbial and enzymatic access to organic matter, suggesting that organic C within MOAs is resistant to decomposition. However, plant roots and rhizosphere microbes are known to transform minerals through dissolution and exchange reactions, implying that
With their superficially shark-like appearance, the Mesozoic ichthyosaurs provide a classic illustration of major morphological adaptations in an ancestrally terrestrial tetrapod lineage following the invasion of marine habitats1, 2–3. Much of what is known about ichthyosaur soft tissues derives from specimens with body outlines4, 5–6. However, despite offering insights into aspects of biology tha
Iron (Fe) concentrations are increasing in lakes on a wide geographical scale, contributing to recent browning of lake waters. As available time series on lake-water Fe concentrations are relatively short, covering the past few decades only, varved lake sediments may provide extended and precisely dated records to study temporal Fe dynamics in lakes in response to environmental drivers, such as ch
Ultrasound Optical Tomography (UOT) combines the high-resolution imaging capability of ultrasound with measurements of light absorption and scattering properties of human tissue. In this work, UOT working at 794.2 nm wavelength and equipped with a spectral hole burning filter was used to image through 5 cm thick tissue phantoms with embedded cubic 12 × 12 × 12 mm3 inclusions at a 2.5 cm depth. In
Abstract: The radiative decays χc1(3872) → ψ(2S) γ and χc1(3872) → J/ψγ are used to probe the nature of the χc1(3872) state using proton-proton collision data collected with the LHCb detector, corresponding to an integrated luminosity of 9 fb−1. Using the B+ → χc1(3872)K+ decay, the χc1(3872) → ψ(2S) γ process is observed for the first time and the ratio of its partial width to that of the χc1(387
Tendons are hierarchically structured and composed of load-bearing collagen. Their hierarchical structure allows the transfer of tensile forces across multiple length scales as loads are partitioned from the whole tendon through fascicles, fibers, and fibrils down to the tropocollagen molecules. To elucidate their structural hierarchical deformation, this study investigated the combined tissue, fi
Supplemental Instruction (SI) is an academic support model with large international prevalence with the purpose of preventing dropouts and strengthen students’ study abilities and results. SI is a collaborative form of learning in groups of about 5-15 students who meet on a weekly basis under the facilitation of an SI-leader, an older student with good insight in the course. The SI-leader helps th
Osteoderms, skeletal structures in the skin, are found in many animals and serve diverse roles. In some lizards, the bony osteoderm has a capping tissue (CT) whose composition and structure remain unknown. Here, the composition and nanostructure of osteoderms from the Mexican beaded lizard (Heloderma horridum) are investigated. The CT is highly mineralized with an extraordinarily high elastic modu
Globular clusters (GCs) are among the oldest and densest stellar systems in the Universe, yet how they form remains a mystery1. Here we present a suite of cosmological simulations in which both dark-matter-free GCs and dark-matter-rich dwarf galaxies naturally emerge in the Standard Cosmology. We show that these objects inhabit distinct locations in the size–luminosity plane and that they have sim
