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BACKGROUND: Drug-coated devices are widely used to reduce restenosis after lower limb revascularisation in patients with peripheral artery disease, but their effect on patient-centred outcomes remains unclear. We assessed the effect of paclitaxel-coated devices on clinically important outcomes in patients with intermittent claudication undergoing infrainguinal endovascular revascularisation.METHOD
BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial
PURPOSE: Groin hernia repair is a common procedure in general surgery, and is taught to and performed by surgeons early in their training. The aim of this observational study was to compare hernia repair performance and results of surgical trainees with those of a specialized surgeon, to identify what factors may influence short and long-term outcome, and areas for improvement in surgical training
Retrieving episodic memories often involves reconstructing both their semantic content and the emotional context in which they occurred. However, the neural mechanisms that differentiate these forms of reinstatement remain poorly understood. This event-related potential (ERP) study examines how semantic category and emotional valence are reinstated during memory retrieval.Seventy participants enco
This chapter critically examines the European Union's (EU) discourse towards the Southern Neighbourhood. The central argument is that, following poststructuralism, the EU's construction of itself as an actor in the region is problematic, given its claims to civilizational values and the imposition of norms of good governance that have been legitimised through the framework of Normative Power Europ
Industrial CO2 emissions, particularly from flue gases, are a major barrier to climate change mitigation. Carbon capture, particularly with bioenergy (BECCS), offers a pathway to negative emissions. This study models an MEA-based carbon capture system using operational data from a stand-alone pulp mill, focusing on its energy impact and optimization strategies. The analysis distinguishes between h
The Age of Liberty gave rise to a unique form of government in Sweden, the world’s first Freedom of the Press Act and civil rights. Beliefs that those in power should be loyal to the people not to God or the monarch, mark the beginning of profound social changes that took hold with the European Enlightenment.
OBJECTIVE: Childhood obesity may impact the risk of islet autoimmunity (IA). The trajectory of BMI through childhood resembles the early peak incidence of first-appearing autoantibodies against insulin (IAA-first) but not GAD65 (GADA-first). We studied whether a child's BMI can impact the age-related risk of first-appearing IA phenotypes.RESEARCH DESIGN AND METHODS: We identified 7,724 children at
Starting with remnants of street art and graffiti from the Orange Revolution of 2004, over the Revolution of Dignity in 2013–14, and ending with street art and graffiti created during Russia’s ongoing war of aggression since 2014, this chapter looks at several cases from Ukraine that showcase the different roles street art and graffiti have played in the country’s democratic process.
A central assumption in neuroscience is that learning mechanisms are conserved across species. Eyeblink conditioning, a cornerstone paradigm for studying associative learning and cerebellar function, has been widely used in humans and animal models alike. Yet direct cross-species comparisons remain rare. In this systematic review, we analyzed 484 eyeblink conditioning experiments reported in 271 s
Hydrogen energy technologies are forecasted to play a critical supporting role in global decarbonisation efforts, as reflected by the growth of national hydrogen energy strategies in recent years. Notably, the UK government published its Hydrogen Strategy in August 2021 to support decarbonisation targets and energy security ambitions. While establishing techno-economic feasibility for hydrogen ene
The feasibility of the global energy transition may rest on the ability of nations to harness hydrogen's potential for cross-sectoral decarbonization. In countries historically reliant on natural gas for domestic heating and cooking such as the UK, hydrogen may prove critical to meeting net-zero targets and strengthening energy security. In response, the UK government is targeting industrial decar
Hydrogen-fuelled technologies for home heating and cooking may provide a low-carbon solution for decarbonising parts of the global housing stock. For the transition to transpire, the attitudes and perceptions of consumers must be factored into policy making efforts. However, empirical studies are yet to explore potential levels of consumer heterogeneity regarding domestic hydrogen acceptance. In r
Decarbonising the global housing stock is imperative for reaching climate change targets. In the United Kingdom, hydrogen is currently being tested as a replacement fuel for natural gas, which could be used to supply low-carbon energy to parts of the country. Transitioning the residential sector towards a net-zero future will call for an inclusive understanding of consumer preferences for emerging
The feasibility of South Africa's just energy transition, as dictated by the speed of phasing out coal and scaling up renewables, will rest on a range of techno-economic, socio-political, and socio-technical factors. Interactions between these dimensions of the transition carry significant implications for energy justice. In response, this paper proposes the Just Transition Feasibility Framework (
Hydrogen energy technologies are anticipated to play a fundamental role in securing a decarbonised energy future. While the deployment of low-carbon hydrogen energy systems remains nascent and is subject to a range of techno-economic constraints, potential scalability will also hinge on social acceptance. In response, this study draws on extensive national survey data to derive a comprehensive typ
National hydrogen strategies are emerging as a critical pillar of climate change policy. For homes connected to the gas grid, hydrogen may offer an alternative decarbonisation pathway to electrification. Hydrogen production pathways in countries such as the UK will involve both the gas network and the electricity grid, with related policy choices and investment decisions impacting the potential co
In an era characterised by political instability, economic uncertainty and mounting environmental pressures, hydrogen fuel is being positioned as a critical piece of the global energy security and clean energy agenda. The policy push is noteworthy in the United Kingdom, where the government is targeting industrial decarbonisation via hydrogen, while exploring a potential role for hydrogen-fuelled
