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Background: ST-segment elevation myocardial infarction (STEMI) is treated with stenting, but the underlying stenosis is often not severe, and stenting may potentially be omitted. Aims: The aim of the study was to investigate outcomes of patients with STEMI treated with percutaneous coronary intervention (PCI) without stenting. Methods: Patients were identified through the DANAMI-3-DEFER study. Ste

Introduction: Functional abdominal pain disorders (FAPDs) are common among girls and has been associated with stress. Cortisol is one of the major stress hormones. Dance and yoga have been shown to reduce abdominal pain among girls with FAPDs. Aim: To investigate the effect of an 8-month intervention with dance and yoga on cortisol levels in saliva among girls with FAPDs. Methods: A total of 121 g

In many ways, the European Union (EU) may be considered a unique foreign policy actor, combining a peculiar institutional design and set of resources with a specific normative agenda for and ambition in global affairs. Through a two-stage analysis, this chapter examines the role self-conception of the EU as it appears from the EU Global Strategy, released in 2016 as the overarching guide for forei

Tensor-valued diffusion encoding facilitates data analysis by q-space trajectory imaging. By modeling the diffusion signal of heterogeneous tissues with a diffusion tensor distribution (DTD) and modulating the encoding tensor shape, this novel approach allows disentangling variations in diffusivity from microscopic anisotropy, orientation dispersion, and mixtures of multiple isotropic diffusivitie

PURPOSESelumetinib can increase radioactive iodine (RAI) avidity in RAI-refractory tumors. We investigated whether selumetinib plus adjuvant RAI improves complete remission (CR) rates in patients with differentiated thyroid cancer (DTC) at high risk of primary treatment failure versus RAI alone.METHODSASTRA (ClinicalTrials.gov identifier: NCT01843062) is an international, phase III, randomized, pl

The reassigned spectrogram is a powerful tool for analysing non-stationary signals, and in an ideal setting it gives perfect time and frequency localisation. A method very well suited for oscillating transient signals is the matched window reassignment, which requires a matching window, i.e. the envelope of the transient, to be known or estimated beforehand. This paper proposes a novel method for

In this paper we propose a novel technique to estimate the parameters of two Gaussian envelope oscillatory signals, with the same time-locations and oscillatory frequencies but possibly different phases. The phase difference and the length of the Gaussian envelope are estimated directly from the slopes of the corresponding cross-spectrogram reassignment vectors. Including the phase difference and

This article takes the phenomenon of phantom limb pain (PLP), and a therapeutic technology designed to treat it, as springboards to critically consider a transformation: from deeply subjective experiences into quantitative data. Drawing upon ethnographic fieldwork on neuroprosthetic development, I examine an international clinical trial coordinated in Sweden using neuromuscular activation, machine

Low rank inducing penalties have been proven to successfully uncover fundamental structures considered in computer vision and machine learning; however, such methods generally lead to non-convex optimization problems. Since the resulting objective is non-convex one often resorts to using standard splitting schemes such as Alternating Direction Methods of Multipliers (ADMM), or other subgradient me

Given a sensor network, TDOA self-calibration aims at simultaneously estimating the positions of receivers and transmitters, and transmitters time offsets. This can be formulated as a system of polynomial equations. Due to the elevated number of unknowns and the nonlinearity of the problem, obtaining an accurate solution efficiently is nontrivial. Previous work has shown that iterative algorithms

Wireless sensor networks are susceptible to jamming attacks that can result in communication breakdowns. Preemptive measures to prevent jamming attacks is an active research field, but to stop an ongoing attack often requires that one is able to locate jammers in order to neutralize them. Several methods exist for the case when the network is corrupted by a single jammer, although these generally

Abstract Transition metals, such as zinc, are essential micronutrients in all organisms, but alsohighly toxic in excessive amounts. Heavy-metal transporting P-type (PIB) ATPases are crucial forhomeostasis, conferring cellular detoxification and redistribution through transport of these ionsacross cellular membranes. No structural information is available for the PIB-4-ATPases, the subclasswith the