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This article demonstrates the value of “scalable reading” of historical travel guides, combining traditional close reading with computer-assisted distant reading. Aiming to scrutinize the persistence of older tourist attractions under communism, we analyse guidebooks intended for similar audiences but produced under different political regimes. More specifically, we compare three travel guides to
For over a decade, jihadi terrorism in Europe, and the recruitment of Europeans to fight for ISIS in Syria, have increasingly involved marginalized youths from a social context of street culture, illegal drug use and crime. Existing theoretical models of the crime-terrorism nexus and radicalization arguably do not sufficiently explain the fluid and dynamic ways by which the street cultural come to
INTRODUCTION: The Five Self-Harm Behavior Groupings Measure (5S-HM) is a novel assessment that evaluates behaviours which may go undetected by existing measures. Self-harm is formulated across directness and lethality spectra, including under-studied behaviors such as indirect self-harm, harmful self-neglect and sexual self-harm. Aims of the study were to: (1) empirically evaluate the 5S-HM; (2) t
Venetoclax (Ven) is a selective B-cell lymphoma 2 inhibitor being studied in t(11;14)+ relapsed/refractory multiple myeloma (MM). Detection of t(11;14) in MM requires bone marrow (BM) aspiration and evaluation of CD138+ plasma cells by fluorescence in situ hybridization (FISH). Innovative techniques may provide less invasive detection of t(11;14) in liquid biopsies Here we present results of the S
Sanitation work in India is largely carried out by the historically marginalized Dalits, formerly known as untouchables, without proper devices or safety gear, as so-called ‘manual scavenging’. To counter manual scavenging, non-governmental organizations (NGOs) have turned to courts and litigation as a form of resistance. This brought about some successes: manual scavenging was repeatedly outlawed
Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. However, methods for SD reconstitution have been unavailable, thereby limiting studies in the field. In the present study, we established human induced pluripotent stem cells (iPSCs) from a patient with an NPHS1 missense mutation, a
IntroductionPostural Orthostatic Tachycardia Syndrome (POTS) is a disorder characterized by excessive orthostatic tachycardia and orthostatic intolerance. While traditional inflammatory biomarkers tend to be normal, a subclinical inflammatory process may be present in POTS.PurposeWe aimed to analyse novel inflammatory biomarkers in POTS patients: Growth Differentiation Factor 15 (GDF15), Neutrophi
Deciphering the genetic basis of prostate-specific antigen (PSA) levels may improve their utility to screen for prostate cancer (PCa). We thus conducted a transcriptome-wide association study (TWAS) of PSA levels using genome-wide summary statistics from 95,768 PCa-free men, the MetaXcan framework, and gene prediction models trained in Genotype-Tissue Expression (GTEx) project data. Tissue-specifi
The climate crisis calls for a new generation of social policy compatible with planetary limits and economic postgrowth circumstances. This article analyses how some of the pillars of such a new generation of social policy may be conceptualized by highlighting commonalities between the most recent IPCC report and the sustainable welfare literature. Methodologically triangulating content analysis o
Small ponds constructed for nutrient retention, biodiversity conservation or recreation also store large amounts of carbon. The potential role of small ponds for carbon storage and greenhouse gas emissions have been highlighted both in the scientific literature and in management plans. The role of small ponds in the global carbon budget is likely significant, but the potential has not been fully eSmall ponds constructed for nutrient retention, biodiversity conservation or recreation also store large amounts of carbon. The potential role of small ponds for carbon storage and greenhouse gas emissions have been highlighted both in the scientific literature and in management plans. The role of small ponds in the global carbon budget is likely significant, but the potential has not been fully e
- An increasingly complex geopolitical landscape puts more emphasis on national interests.- The pressures from knowledge securitization need to be handled in order to alsomeaningfully address the needs and opportunities presented by global scientificcollaboration.- Research integrity, ethics, research security, knowledge securitization, equity, andresponsible internationalization need to be consid
Parks and other public spaces play an important role in working class formation. Yet, these placeswere often provided for urban populations by philanthropic elites who in turn set the, oftenunambiguously authoritarian, terms of use. In the Swedish city Malmö, the social democratic labormovement acquired a public park run by the movement itself in 1893 and proclaimed it “ThePeople’s Park”, mimickin
PURPOSETo assess interval cancer rate in a large, prospective digital breast tomosynthesis (DBT) screening trial in comparison with a concurrent screening population and to assess tumor characteristics of interval cancers in DBT-screening.METHOD AND MATERIALSThe prospective ****Trial, comparing digital breast tomosynthesis (DBT) with digital mammography (DM) in 14,848 women has shown a significant
Whipple´s disease is a rare multisystem condition affecting < 1/1.000.000 per year. The condition often presents with polyarthritis, diarrhea, and intestinal malabsorption. Endocarditis is seen in a minority of these patients, and is typically culture negative, as the causative agent Tropheryma whipplei does not grow in ordinary culture media. We present the case of a 78-year-old man with a histor
Background: Pre-anaesthesia assessment is crucial to ensure the quality and safety of anaesthesia and surgery. However, despite being very common and essential for many patients undergoing elective surgery, little is known about the different pre-anaesthesia assessment approaches. Hence, this article outlines a study protocol for a scoping review aiming to, systematically, map the literature on pr
