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An Epidemiological Study of Exhaustion in the Context of Chronic stress. Concept, Cortisol, Causes and Consequences
Popular Abstract in Swedish Intresset för utmattning har ökat både i Sverige och internationellt under de senaste årtiondena. Utmattning som begrepp är oklart definierat vetenskapligt, och det finns olika benämningar på utmattningstillstånd, som till exempel den något gammalmodiga benämningen neurasteni, som ännu finns kvar som diagnos-klassifikation (där även benämnt ”trötthetssyndrom”), kronisktThe interest in exhaustion has increased rapidly during the last few decades in many developed countries. In Sweden, prevalence of exhaustion increased by 50 percent on average between 1989 and 2005, and recent data reveals that exhaustion still remains at this higher level. Scientifically, exhaustion is not clearly defined. Chronic stress is acknowledged to give rise to exhaustion, but specific m
Ventilated Trombe wall as a passive solar heating and cooling retrofitting approach; a low-tech design for off-grid settlements in semi-arid climates
In the coming years, it is anticipated that if we continue with the same pace of energy consumption, communities will continue to face three major challenges; a mounting increase in energy demands, pollution, and global warming. On a local scale, Egypt is experiencing one of its most serious energy crises in decades. The energy consumed in indoor cooling and heating is the biggest portion of total
Production of pions, kaons and protons in pp collisions at root s=900 GeV with ALICE at the LHC
The production of pi(+), pi(-), K+, K-, p, and (p) over bar at mid-rapidity has been measured in proton-proton collisions at root s = 900 GeV with the ALICE detector. Particle identification is performed using the specific energy loss in the inner tracking silicon detector and the time projection chamber. In addition, time-of-flight information is used to identify hadrons at higher momenta. Finall
Kan musselodlingar rena Östersjön?
Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon
Popular Abstract in Swedish När vi äter socker frisätter kroppen hormonet insulin från specifika beta-celler i bukspottskörteln för att förmå muskelceller och fettceller att ta upp sockret från blodet och därmed återställa blodets sockerbalans. Vid övervikt blir dessa vävnader resistenta mot insulinets verkan vilket leder till att sockret stannar kvar i blodet. Detta vill kroppen undvika då en förThere are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. hyperglucagonemia, for the development of beta-cell dysfunction in pre-diabetic mice. We found that i
Alpha-1-microglobulin: Innate defence against pathological oxidation
Oxidative stress has been implicated as an important factor in the progression of many diseases. An imbalance in the redox-system may cause oxidation of cells and molecules, which might subsequently lead to tissue damage. The research presented in this thesis has focused on elucidating a possible involvement of the human protein alpha-1-microglobulin in the defence against pathological oxidation.
Molecular Weight Determination by Counting Molecules
Molecular weight (MW) is one of the most important characteristics of macromolecules. Sometimes, MW cannot be measured correctly by conventional methods like gel permeation chromatography (GPC) due to, for example, aggregation. We propose using single-molecule spectroscopy to measure the average MW simply by counting individual fluorescent molecules embedded in a thin matrix film at known mass con
Genetic loci influencing kidney function and chronic kidney disease
Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into me
Three Jewish Polemicists of Aragonia
The polemics of Solomon Adret, Bahya ben Asher, and Abraham Bibago are presented, based on my book: Shield and Sword. 1993.
Remembering the Chaos - But Life Went on and the Wound Healed. A Four Year Follow Up with Parents having had a Baby with Infantile Colic.
OBJECTIVE: To elucidate parent´s experience of having had a baby with colic four years previously and of how the colic and care influenced the family in a long-term perspective. METHODOLOGY AND PARTICIPANTS: A qualitative inductive follow-up study with 13 individual and one focus group interview including four parents. Altogether ten mothers and seven fathers representing 12 families, who had been
Measurement of the production and lepton charge asymmetry of W bosons in Pb plus Pb collisions at root s(NN)=2.76 TeV with the ATLAS detector
A measurement of W boson production in lead-lead collisions at root s(NN) = 2.76 TeV is presented. It is based on the analysis of data collected with the ATLAS detector at the LHC in 2011 corresponding to an integrated luminosity of 0.14 nb(-1) and 0.15 nb(-1) in the muon and electron decay channels, respectively. The differential production yields and lepton charge asymmetry are each measured as
The Invisible Suffering: Sexual Coercion, Interpersonal Violence, and Mental Health - A Cross-Sectional Study among University Students in South-Western Uganda.
Despite a history of conflicts and widespread human rights violation in sub-Saharan Africa, little is known about the prevalence of interpersonal violence among the population in this region. Evidence from high-income countries suggests that exposure to violence has mental health consequences and violence also has associations with experiences of sexual coercion.
Ljud och tystnad för sinne och själ : betydelser av ljud och tystnad för själslig och mental rekreation
Ljud och tystnad för sinne och själ - om betydelser av ljud och tystnad för själslig och mental rekreation (seminarium 28 november 2008) Innehåll: Henrik Karlsson: Om tystnaden får tala, Owe Wikström: Vad tyst det blev!, Håkan Svenbro: Meditation över tystnad, Antoon Geels: Tystnadens röst och själens musik.
The EU as a Normative Success for National Minorities. Before and after the Enlargement.
Concurrent validity of the Executive Function Performance Test in people with mild stroke
Introduction: Studies have shown that executive dysfunction is common in adults after stroke. Occupational therapists working in acute care assess the performance of activities of daily living; most instruments focus on personal care. However, the assessment of instrumental activities of daily living has been shown to discriminate executive dysfunction more effectively. An instrument for assessing
On the brink between extinction and persistence
The nature of size fluctuations is crucial in forecasting future population persistence, independently of whether the variability stems from external forces or from the dynamics of the population renewal process. The risk of intercepting zero is highly dependent on the way the variance of the population size relates to its mean. The minimum population size required for a population not to go extin
Learning Basis Skills by Autonomous Segmentation of Humanoid Motion Trajectories
Manipulation tasks are characterized by continuous motion trajectories containing a set of key phases. In this paper, we propose a probabilistic method to autonomously segment the motion trajectories for estimating the key phases embedded in such a task. The autonomous segmentation process relies on principal component analysis to adaptively project into one of the low-dimensional subspaces, in wh
Bumblebee flight performance in environments of different proximity.
Flying animals are capable of navigating through environments of different complexity with high precision. To control their flight when negotiating narrow tunnels, bees and birds use the magnitude of apparent image motion (known as optic flow) generated by the walls. In their natural habitat, however, these animals would encounter both cluttered and open environments. Here, we investigate how larg
Detection and interactive isolation of faults in steam turbines to support maintenance decisions
The maintenance of steam turbines is expensive, particularly if dismantling is required. A concept for the provision Of Support for the maintenance engineer in determining steam turbine status in relation to the recommended maintenance interval is presented here. The concept embodies an artificial neural network which is conditioned to recognise patterns known to be related to faults. The faults S
