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Synthesis of glucuronic acid derivatives for further studies of the inhibitory effect of dermatan sulfate epimerase 1

Kolhydrater är en grupp av biomolekyler som omfattar sockerarter, både enstaka och sammankopplade i kedjor. Förutom att förse våra celler med energi har kolhydrater en rad viktiga funktioner, från att vara involverade i kommunikationen mellan celler till cellulär uppbyggnad. Syntesen av kolhydrater i våra celler behöver undersökas ytterligare eftersom det finns samband mellan ett antal sjukdomar oGlycosaminoglycans comprise linear polysaccharide containing repeated disaccharide units. When one of the disaccharide units of chondroitin sulfate, glucuronic acid, gets epimerized by dermatan epimerase 1 to iduronic acid, dermatan sulfate is formed. Dermatan sulfate is essential in tumorigenesis, due to increased flexibility in the chain and enables interaction with certain proteins such as cyto

“Den här lilla gangstern är det inte lönt att fråga” – En analys av medlares förklaringar om medlingens praktik och hinder

Dagens alltmer retributiva kriminalpolitik utgör en bakgrund till att medling vid brott för unga lagöverträdare har identifierats som ett ämne som är värt att undersöka närmare. Studiens syfte är att belysa hur medlare i Skåne beskriver och uppfattar medlingens praktik, med fokus på de hinder som medlingsverksamheten står inför och som tycks begränsa dess potential. Empirin består av sex intervjue

Product Life Extension: A Quantitative Analysis of Economic Value Retention in a Circular Economy Business Model

This study investigates the creation of economic value within the Product Life Extension (PLE) business model, focusing on how specific product categories and characteristics impact the retention of value and revenue streams of PLE firms. Using Godsinlösen AB as a case study, the research quantitatively examines sales data to explore the retention of product value and consumer preferences for reus

Disclosure differences between mandatory and voluntary sustainability reporting regimes -- A comparison between Chinese and Italian manufacturing companies

This study examines the sustainability reporting practices of firms in Italy (mandatory disclosure) and China (voluntary disclosure). Using a qualitative descriptive design and content analysis with NVivo, the sustainability reports of large manufacturing companies with high ESG ratings from both countries are analyzed based on GRI guidelines. Institutional theory is applied to understand the infl

Tätortsnära strandskydd - Intresseavvägningar och möjligheter i miljöbalken & plan och bygglagen

Strandskyddet i Sverige har en lång historia och har länge varit viktigt för att skydda allemansrätten och på senare tid även djur- och naturvärden, trots detta är lagstiftningen polariserande och ofta debatterad. Skyddet gäller vid landets alla vatten och innebär att byggnads- eller anläggningsåtgärder inte får utföras inom 100 meter från strandlinjen. Regleringen hittar vi främst i miljöbalken oThis thesis strives to investigate and make sense of the complex regulations surrounding the availability of exploitable land along bodies of water in Sweden. With the Shore Protection regulations found in the Swedish Environmental Code it becomes apparent that most sought after land along the sea, lakes and running water for planning and construction in accordance to the Planning and Building Act

"Family Ties and ESG Lies: Decoding Sustainability in Swedish Businesses"

The purpose of this study is to examine the influence of family ownership, the CEO's role, and the chairman's position on ESG decoupling in Swedish firms during the years 2016-2022. The study aims to provide insights into the complexities of ESG decoupling within family-owned companies and contribute to the understanding of sustainability efforts in these specific ownership structures.

Åtgärder för att underlätta för patienter med ångest och oro vid MR- undersökning

Magnetresonanstomografi (MR) är en vanlig medicinsk bildteknik som tydligt framhäver små strukturer i kroppen utan att använda joniserande strålning. Ångest och oro hos patienter är vanliga orsaker till att MR-undersökningar avbryts eller blir inställda. Detta är negativt för både patientens vårdförlopp och för röntgenverksamheten. Därför är det viktigt att röntgensjuksköterskor har kunskap om oli

Japanese Vocabulary Acquisition Among Swedish Natives a Study Across JLPT Levels and Word Classes

This thesis examines the acquisition of Japanese vocabulary by Swedish L1 speakers learning Japanese as a second language, and how well their proficiency, acquired through formal education in Sweden, aligns with the Japanese Language Proficiency Test (JLPT) standards. The study also compares the recognition rates of different types of word classes such as nouns, adjectives, and verbs across variou

Determination of the pH dependency of chemical shifts

NMR (nuclear magnetic resonance) spektroskopi, är en omfattande teknik som har många applikationer inom kemin. Det kan användas inom organisk kemi som stöd och underlag till strukturbestämning av molekyler, men framför allt finns det många tillämpningar inom biokemi och molekylärbiologi där tekniken utnyttjas; NMR är mycket användbart för att studera biomolekylers strukturer och biologiska processThis study aims to present a protocol for pH determination in biomolecular NMR samples by evaluating the pH dependence of chemical shifts in the most commonly reported buffer molecules in the BioMagResBank (BMRB). Whilst there exists multiple methods and protocols for intrinsic NMR pH determination and various molecules have been proposed as pH indicators, there is no method to determine the actua

Estimating the Impact of ESG scores on Firm Value and Cost of Capital: A Quantitative Study Across European Firms

Title: Estimating the Impact of ESG scores on Firm Value and Cost of Capital - A Quantitative Study Across European Firms Purpose: The purpose of this paper is to investigate the impact of Environmental, Social, and Governance (ESG) scores on firm value and cost of capital across various market capitalizations, with a focus on small, mid, and large cap companies in the European Union. Methodology:

Från industri till kultur

In the 21 century many post industrial cities have converted their former areas into cultural areas with entertainment areas, cultural schools and museums. The city of Malmö has transformed itself into a city of culture and it uses its place brand to compete for tourists, inhabitants, businesses and labor with other cities. The purpose with this paper is to find out how culture is included in the

“Makt har den som får sin vilja igenom trots motstånd” En kritisk diskursanalys av remisser för utvidgad preventiv avlyssning

In a time where increased crime consistently dominates the political agenda and the population is continually reminded of acts of violence and shootings, a new legislative proposal regarding surveillance raises not only suspicion of wrongdoing, but questions regarding integrity. From a socio-legal perspective, concepts such as hegemony can elucidate how the state formulates and justifies laws and

Software-Driven Calibration Method for a Pick-and-Place Process

Machine calibration is important for optimal performance throughout the lifespan of industrial processes. A prime example is the pick-and-place process, where robots must manipulate objects accurately. Currently, this process is manually calibrated, which can be a complex practice. This thesis studies a software-based approach to error detection within the process, aiming to reduce the need for ma

Optimization of antenna array layouts in planar and non-planar geometries for DoA estimation

The use of antenna arrays allows for direction-of-arrival (DoA) estimation in a radar system. The antenna elements in an array are conventionally positioned equidistantly on a grid, but they can also be placed relatively freely to form sparse antenna arrays. These non-conventional layouts could potentially offer improved DoA capabilities. In this work, a particle swarm optimization algorithm has b

Bad Apples, Social Capital and Human Capital in El Salvador: Evidence from Salvadoran High School Students

This study investigates the impact of classroom conflict and social cap- ital on different measures of human capital accumulation in middle school and high school students from El Salvador. Using class-level measures of mutual enmity and friendship obtained through network analysis and exploiting exogenous variation in the proportion of students who have repeated the school year, I obtain consiste

Naturliga Bundsförvanter: En kritisk diskursanalys av EU:s ramverk för utvecklingssamarbetet med Afrika

The partnership and development cooperation between the European Union (EU) and Africa is described as a key priority for the European Commission and their aim is to further strengthen the partnership (European Commission 2020). However, the relationship between the European Union and the African continent has a deep and complex history that has been characterized by colonial ties and unequal powe

Inflation and Currency Depreciation in Argentina - A Historical Institutional Perspective on Inflation in Argentina

Argentina, once among the world's wealthiest nations, has since the 1950s experienced economic turmoil marked by high inflation and currency depreciation. This thesis investigates the historical factors contributing to Argentina's persistent issues with inflation, with particular emphasis on the economic policies made since the 1940s. The study employs a historical institutionalism framewo