Filtyp
Background Illicit use of methadone and buprenorphine has been described as a growing problem in Sweden in recent years, and has been associated with an increased drug-related mortality. Critics claim that the substances have become popular among adolescents and that they function as a gateway to heroin use. The aim of this study is to investigate, firstly, the extent to which illicit use of metha
Background In this study we examine whether the association between internet use and drinking could be different for different types of internet activities among adolescents. We also adjust for a number of theoretically relevant factors such as peer influence, unstructured activities, impulsivity and parental monitoring. Method The data are drawn from four cross-sectional surveys from the years 20
Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML cells aberrantly express the lymphoid surface protein SLAMF6 (signaling lymphocyte activation molecule family member 6). Knockout of SLAMF6 in AM
Purpose – The aim of this study is to empirically explore how contractual learning in public procurement is affected by organizational design. Design/methodological approach – Two inductive case studies based on semi-structured interviews and document analysis. Findings – We find that the consolidation of economic, technical and legal tasks in specific units can strengthen contractual learning in
Background: Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with lower bone mineral content (BMC) and density (BMD) in children, but prospective studies remain limited. We aimed to investigate associations between prenatal and childhood PFAS exposure and BMC/BMD at age 9 years, following up on our previous findings from age 7 years. Methods: We used data from the Odense
The importance of older adults’ participation in policymaking is increasingly recognized, but the nuanced participation processes remain insufficiently understood. This scoping review aims to map existing research on older adults’ participation in policymaking, focusing on who participates, their activities and contributions, resulting outputs and outcomes, and the enablers and barriers affecting
Interest in Jane Austen’s fiction and life has never been greater than today. Her narrative works and worlds live on 200 years after their publication not only through their own popularity, but also through numerous re-presentations in the forms of novels, movies, television series, and fan fictions that keep flourishing from her fictional worlds and characters. Austen’s novels, her settings, and
Denna avhandling utvecklar och utvärderar språkbaserade bedömningar som använder artificiell intelligens (AI) för att omvandla öppet språk till kvantitativa indikatorer och beskrivningar av psykiska hälsorelaterade konstruktioner. Medan slutna skalor länge har dominerat psykologiska bedömningar, är de begränsade av fasta svarsformat och kanske inte helt fångar komplexiteten i individers upplevelseThis thesis develops and evaluates language-based assessments that use artificial intelligence (AI) to transform open-ended language into quantitative indicators and descriptions of mental health related constructs. While closed-ended scales have long dominated psychological assessment, they are limited by fixed response formats and may not fully capture the complexity of individuals’ experiences.
BackgroundIbrutinib, a Bruton tyrosine kinase inhibitor, prolongs progression-free survival when added to immunochemotherapy as first line treatment. The ENRICH trial compared the chemotherapy-free combination of ibrutinib and the anti-CD20 antibody rituximab (ibrutinib–rituximab) with standard immunochemotherapy (R-CHOP [rituximab–cyclophosphamide, doxorubicin, vincristine, and prednisolone] or b
AI-enhanced search applications are evolving rapidly, promising to answer complex queries with simple answers, but this creates new challenges on how users evaluate the information presented to them. This study investigates how four AI-enhanced search applications (ChatGPT, Gemini, Copilot and You.com) respond to questions about erectile dysfunction drugs in Sweden, which risks creating digital gr
Digital Transformations of Illicit Drug Markets: Reconfiguration and Continuity is authored by leading experts in the field of illicit drug sourcing, who draw on their interdisciplinary backgrounds to illustrate how modern technologies are embedded within our social structures. Since the digital (r)evolution, the sourcing of illicit drugs now takes place through smartphones, encryption, social med
