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PURPOSE: To study newly diagnosed glaucoma patients given mono- or multi-therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction.METHODS: Patients newly diagnosed with manifest primary open-angle glaucoma and included in the Glaucoma Intensive Treatment Study (GITS) were randomized to immediat

Vi kryllar av bakterier. De bor framför allt i vår tjocktarm där de lever på de delar av vår mat som vi inte kan ta hand om själva. I utbyte omvandlar bakterierna en del av maten de äter till vitaminer och fettsyror som är viktiga för oss. Det bor flera olika arter av bakterier i vår tarm som äter lite olika saker, eftersom det är ont om mat för så många har de flesta specialiserat sig för att minHuman gut bacteria utilise different types of polysaccharides present in our diet. One of these polysaccharides is galactomannan. Many organisms in the phylum Bacteroidetes have gene clusters encoding for all proteins required for hydrolysis, binding and transport of one type of polysaccharide, called polysaccharide utilisation loci (PULs). A PUL from the human gut bacterium Bacteroides ovatus was

The genera Coppinsiella and Seawardiella are described based on the combined phylogenetic analysis from ITS nrDNA, 28S nrLSU and 12S mtSSU sequences. The affinities of the new genera Orientophila, Athallia, Flavoplaca and Calogaya are discussed. The former Caloplaca lobulata group (or ‘Xanthoria lobulata-Gruppe’ sensu Steiner et Poelt 1982) found to be positioned in the Calogaya clade based on ITSThe genera Coppinsiella and Seawardiella are described based on the combined phylogenetic analysis from ITS nrDNA, 28S nrLSU and 12S mtSSU sequences. The affinities of the new genera Orientophila, Athallia, Flavoplaca and Calogaya are discussed. The former Caloplaca lobulata group (or ‘Xanthoria lobulata-Gruppe’ sensu Steiner et Poelt 1982) found to be positioned in the Calogaya clade based on ITS

Even though there is persuasive evidence to support the association between income distribution and health, research in the field is still progressing. There are questions, for instance, about the significance of the association in different countries and about the mechanisms linking income distribution and health. Addressing these issues, this doctoral thesis explores the influence of income dist

An experimental setup for microwave stimulation of a turbulent flame is presented. A low-swirl flame is being exposed to continuous microwave irradiation inside an aluminum cavity. The cavity is designed with inlets for laser beams and a viewport for optical access. The aluminum cavity is operated as a resonator where the microwave mode pattern is matched to the position of the flame. Two metal me

Generaliserad tillit till andra människor är både en individuell psykologisk egenskap och en kollektiv egenskap hos sociala kontexter/samhällen. Vissa författare betraktar tillit som en aspekt av socialt kapital. Tillit formas genom vänskapliga relationer, ömsesidighet, ömsesidig hjälp, jämlika relationer, samarbete och optimism och jämlikhet och religion under tonåren och vuxenlivet. Speciellt mi

Inspired by Putnam’s study of Italy, this chapter develops applications that test the issue of social capital and health in the context of social epidemiology. Three central concepts are explained. The chapter attends to the technical issues, including, for example, the portion of children in subgroups identifying conflicts. The author then comes to his main message: the value of longitudinal expe

Somatic variations are frequent and important drivers in cancers. Amino acid substitutions can yield neoantigens that are detected by the immune system. Neoantigens can lead to immune response and tumor rejection. Although neoantigen load and occurrence have been widely studied, a detailed pan-cancer analysis of the occurrence and characterization of neoepitopes is missing. We investigated the pro

Sweet proteins are an unexploited resource in the search for non-carbohydrate sweeteners mainly due to their low stability towards heating. Variants of the sweet protein monellin, with increased stability, were derived by an in vivo screening method based on the thermodynamic linkage between fragment complementation and protein stability. This approach depends on the correlation between mutational