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Phylogenetic and Drug-Resistance Analysis of HIV-1 Sequences From an Extensive Paediatric HIV-1 Outbreak in Larkana, Pakistan

Introduction: In April 2019, an HIV-1 outbreak among children occurred in Larkana, Pakistan, affecting more than a thousand children. It was assumed that the outbreak originated from a single source, namely a doctor at a private health facility. In this study, we performed subtype distribution, phylogenetic and drug-resistance analysis of HIV-1 sequences from 2019 outbreak in Larkana, Pakistan. Me

Management, treatment and prognostic significance of lateral lymph node metastases in rectal cancer—a regional cohort study

Purpose: Lateral lymph node metastases in rectal cancer remain a clinical challenge. Different treatment regimens have been suggested. This retrospective regional cohort study examines outcome after combined oncological and surgical treatment of MRI-positive lateral lymph nodes (LLN). Methods: Data from the Swedish Colorectal Cancer Registry (SCRCR) and patient records were used for retrospective

DETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Di

Plant-wide modelling and analysis of WWTP temperature dynamics for sustainable heat recovery from wastewater

Wastewater heat recovery upstream of wastewater treatment plants (WWTP) poses a risk to treatment performance, i.e. the biological processes. In order to perform a sustainability analysis, a detailed prediction of the temperature dynamics over the WWTP is needed. A comprehensive set of heat balance equations was included in a plant-wide process model and validated for the WWTP in Linköping, Sweden

Good men gone bad? : Resistance to monastic reform in the tenth and eleventh centuries

Conservative opponents of monastic reform in the tenth and eleventh centuries have traditionally been portrayed as principally reluctant to change and unwilling to abandon privileges and preferential treatment. This article performs a close, comparative reading of the poem Carmen ad Rotbertum regem by Adalbero of Laon (c.950–1031) and the monastic chronicle Casus Sancti Galli by Ekkehard IV (c.980

Våld och Visioner : Möten med högre makter i Peter de Dusburgs Cronica Terre Prussie

The Cronica Terre Prussie by Peter de Dusburg (c. 1330) chronicles the expansion ofthe Teutonic Order into Prussia and the Baltic region. Predominantly occupied witharmed conflict, the work also contains a considerable number of accounts of miraclesand wonders, the contents of which have not previously been studied as a corpus.This article attempts a quantitative and qualitative analysis of these

Introduction to Living Standards in the Past

In the introduction, different contributions are brought together in an analysis of pre-industrial living standards in East and West, viewed in the light of the general debate on these issues from the classical economists to present times. The general picture emerging is not one of great divergence, but instead one of considerable similarities. Regional differences within Europe or Asia were often

Bridge Scour : Basic Mechanisms and Predictive Formulas

This report aims at presenting basic knowledge on bridge scour and the processes governing its evolution as well as summarizing the most common formulas used to calculate scour depth at bridges. Design procedures concerning bridge scour in several different countries are also discussed, including United States, Australia, and the United Kingdom. The situation in Sweden with regard to bridge scour

New Evidence on the Standard of Living in Sweden during the Eighteenth and Nineteenth Centuries : Long-Term Development of the Demographic Response to Short-Term Economic Stress

Presents a new view of the standard of living development in Sweden during the agricultural revolution, using evidence on the ability to overcome short-term economic stress. The results corroborate previous findings, based on a variety of indicators, that standard of living in Sweden increased for most people after the mid-nineteenth century, but also support a more negative view of the immediate

Brand orientation : Tensions and conflicts in public management

Public institutions such as cities, the police or schools are increasingly adopting a brand orientation, understood as an approach to organization aiming to create coherence around image and identity, such that consistent, precise and coherent messages can be presented about the organization to internal and external stakeholders. This may be seen as an expression of what is sometimes called “brand

Firearm-Related Homicide in Sweden : A Latent Class Analysis of Suspected Offenders

Sweden has witnessed a significant increase in the rate of firearm-related homicide. We therefore aimed to study the characteristics of individuals suspected of homicide, attempted homicide, preparation to commit homicide as well as conspiracy to commit homicide with a firearm in Sweden. By using information from different registers, suspected individuals between 2000 and 2017 and aged 15 to 60 we

Socioeconomic inequalities in death from past to present : An introduction

In the early postwar period, improvements in life expectancy in many Western countries made health authorities, health scientists and politicians believe that social differences in mortality converged. The assumption was that inequality, when measured as death rates, was on steady decline, possibly even on the brink of disappearing. The question is then, how far back in time can social differences