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Immunotherapy aims to enhance the immune system’s response to cancer. Different immunotherapies exist, such as cytokine therapies and immune checkpoint inhibitors. The FDA has approved immunomodulatory drugs, such as Proleukin, a recombinant IL-2 cytokine, Nivolumab, and Avelumab, which are immune checkpoint inhibitors. However, these drugs lead to side effects in patients known as immune-related
Dwarf galaxies are a key component in understanding the evolution of galaxies and provide tests on the standard cosmological $\Lambda$ Cold Dark Matter model. According to the formation hierarchy, dwarf galaxies are the pieces that create all galaxies. Our current understanding of dwarf galaxies faces discrepancies between theory and observations. These problems are mostly due to incompleteness in
The ECJ’s judgment of 27 January 2021 in the case C-595/18 P (the ”Goldman Sachs case”) has caused a big buzz in the ever growing Private Equity sector. It confirmed the ruling of the GCEU of July 2018 case T-419/14 which in turn confirmed the Commission’s decision according to which Goldman Sachs has been held liable for an antitrust infringement committed by one of its portfolio companies. In al
The Kaczmarz method is an iterative method for solving linear systems of equations. The Kaczmarz method has been around since it was developed by Kaczmarz 1937. The main idea behind the original Kaczmarz method is to orthogonally project the previous x_k onto the solution space given by a row of the system. The block Kaczmarz on the other hand orthogonally projects the previous x_k onto the soluti
This paper analyzes the existence of market power on the Nordic electricity market between 2018-2022, and if the energy market turbulence caused by covid-19, and later deepened following the war in Ukraine affected producers' bidding behavior. Market power was tested using Cournot assumptions to see if producers withheld output strategically when demand was more inelastic. Auction data on syst
I den här uppsatsen undersöks de konflikter som barnmorskor i Sverige upplevde under perioden 1888-1905. Detta görs via kvalitativ analys av de insändare barnmorskor skrev till tidsskriften Jordemodern. Från dessa identifieras tre grupperingar som barnmorskor upplevde konflikter med: lokalsamhället, oexaminerade förlossningsbiträden samt annan vårdpersonal och andra barnmorskor. Konflikterna med a
Employing enzymes as catalysts in the production of chiral amines that are both used as building blocks and active pharmaceutical ingredients might be promising due to milder reaction conditions compared to non-biological catalysts, exclusion of heavy metals, high selectivity towards substrates and precision in chirality of the products. Transaminases are attractive for the use in this process. In
The global food industry is the second main contributor to climate change whilst climate change also poses threats to future food security (Ritchie & Roser, 2020). One of the suggestions to decrease the environmental footprint of consumption and increase the resilience of food systems, is the shift to local production and consumption (Stein & Santini, 2021; Van Gameren et al., 2015). Howev
Purpose: To understand how B2B companies may establish and maintain trust in their relationships with customers during and in the post-COVID digital business landscape. Methodology: The study carries a qualitative approach conducted with an exploratory nature. To establish a comprehensive perspective, broad analysis was conducted by holding seven semi-structured interviews with highly knowledgeab
The objective of this paper is to investigate how Switzerland’s trade outcomes would have evolved had it decided to join the EU. Using the 1995 EU enlargement for identification, the synthetic control method is applied to construct a counterfactual scenario in which Switzerland joined the EU in 1995 together with Sweden, Finland, and Austria. Comparing the actual and the synthetic bilateral trade
Dissolved inorganic carbon (DIC) is a pivotal component of the carbon cycle and is sensitive to environmental disturbances. In the context of the Tibetan Plateau, its spatial and temporal variations in DIC concentrations and flux have substantial implications for regional and global carbon cycles, which, however, remains poorly understood. This study harmonized a large database of riverine DIC obs
An increasing amount of youths in the municipality of Lund have communicated experiences with sexual exploitation, according to the municipal organization Fältgruppen. The aim of this paper is therefore to map the occurrence of sexual exploitation amongst 15 to 20 year olds in the municipality of Lund. To achieve this, a quantitative survey was carried out which was distributed to the target group
Titel: Travsporten, från fysiskt till digitalt. Seminariedatum: 1 juni 2023 Ämne/kurs: FEKH29 - Examensarbete i marknadsföring på kandidatnivå, 15HP Författare: Albin Sopi, Jonathan Pålsson, Karl Bäck Handledare: Veronika Tarnovskaya Nyckelbegrepp: Marknadsmixen, The Sports Product, Travsportens struktur, Omvärldsmiljö, Marknadsföring av travsporten Problem/forskningsfråga: Hur har marknadsf
The waste management and production of plastic play a concerning part in global warming and continues to have a negative effect on the environment. A promising strategy to address this challenge is to develop new sustainable materials, to replace current fossil-based plastics. Cellulose is of interest to be used for bio-based materials since it has many desired properties. However, it lacks the fo
To mitigate climate change and reach Sweden’s goal of becoming carbon neutral by 2045, or at an earlier stage of 2030 for 23 Swedish cities, urgent action is required to reduce greenhouse gas emissions. Due to the building sector’s significant contribution to carbon emissions, a crucial aspect in achieving these goals is improving the energy efficiency of existing buildings, as most of these will
Political instability enhances the risk of armed conflicts, which not only pose a great threat to human livelihoods, but are also capable of negatively impacting the environment, hence making it essential to examine their ecological effects. Armed conflict and its influences on ecosystems are compound and challenging to examine due to limiting accessibility to the concerned regions given the dange
The purpose with the thesis is to investigate whether a change in a target firm's capital structure complexity has an impact on the acquisition premium paid by the acquirer, and whether this effect changes during times of banking and/or market crises. The sample consists of 618 M&A deals with public firms based in the US, Canada, and Europe during 2004–2022. The thesis presents findings in
In providing public goods, the government confronts challenges in determining the optimal pricing strategy due to the lack of information on individual preferences and the propensity of consumers to misreport their true valuations. Decentralisation of fiscal authority could be a partial solution to this problem, as lower government levels have better access the diverse regional and local preferenc
