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Lakes provide critical ecosystem services and are therefore particularly sensitive to disruptions such as harmful algal blooms (HABs). Cyanobacteria are the most common HAB-forming species in lakes, and their prevalence is expected to increase with climate change. However, during a 2018 heatwave in southern Sweden, Lake Vombsjön experienced an unexpected shift from its usual cyanobacterial dominan
Disinhibition of the mechanistic target of rapamycin (mTOR) pathway has been observed in patients with loss-of-function variants in the disheveled, Egl-10, and pleckstrin domain-containing protein 5 (DEPDC5), and nitrogen permease regulator-like proteins 2 and 3 (NPRL2, and NPRL3) genes, which encode the components of GTPase activating protein Activity Toward Rags Complex 1 (GATOR1) complex. Evero
The Chambolle–Pock method is a versatile three-parameter algorithm designed to solve a broad class of composite convex optimization problems, which encompass two proper, lower semicontinuous, and convex functions, along with a linear operator L. The functions are accessed via their proximal operators, while the linear operator is evaluated in a forward manner. Among the three algorithm parameters
Objective: Assessing psychological pain is crucial for evaluating suicide risk. This study examined differences in psychological pain between patients with suicide attempts, those with suicidal ideation, clinical, and non-clinical controls using a newly translated German version of the Mee-Bunney Psychological Pain Assessment Scale (MBPPAS). Method: A cross-sectional study was conducted with two i
Epileptic seizure prediction holds the potential to enhance the quality of life for individuals with epilepsy by enabling the possibility of timely administration of medication and first aid, as well as preventing subsequent accidents. In this paper, we consider the well-established Heart Rate Variability (HRV) and Lorenz features, and augment them with the electrocardiogram (ECG) multifractality
Att läsa och tolka nedtecknade vittnesmål kan öka vår förståelse för hur covid-19-pandemin påverkade vårdpersonal både mentalt och fysiskt. I den här artikeln undersöker vi några av de jobbrelaterade och existentiella svårigheter som läkare mötte under pandemin när det gällde personlig hälsa och välbefinnande. Artikeln använder sig av några av de berättelser som publicerades i amerikansk kontext u
Purpose: The PET Response Criteria in Solid Tumours (PERCIST) 1.0 provides a standardized framework for evaluating treatment response using [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography – computed tomography (PET-CT), but its clinical use is hindered by manual complexity. This study presents coPERCIST, an artificial intelligence (AI)-assisted module integrated into the RECOMIA pl
The hippocampus, crucial in cognitive aging and Alzheimer’s disease (AD), shows early atrophy during disease progression. This study investigated 5-year trajectories of hippocampal volumes across AD stages, focusing on genetic predisposition to AD, captured through the polygenic risk score for AD (PRS-AD) and APOE, and their impact on hippocampal atrophy. Analyzing data from 1,051 participants in
Strategic sustainability communication in organizations managed by financial objectives is characterized by paradoxical tensions that arise within the organization when sustainability goals are added. Yet the dominant perspective on sustainability among practitioners and researchers is the Business Case Frame (BCF) which is ill-suited to address these tensions. This chapter is built on a qualitati
Introduction/Objective: Hepatocellular carcinoma (HCC) is a highly heterogeneous malignant tumor, characterized by elevated mortality rates and poor diagnostic outcomes. Accurate identification of cancer subtypes is crucial for guiding personalized treatment and improving patient prognosis. Methods: A method for precisely identifying HCC subtypes by integrating multi-omics data was presented. This
Drawing on a constitutive understanding of strategic communication [Falkheimer and Heide (Strategic communication: An introduction. Routledge, 2018), (Strategic communication: An introduction to theory and global practice. Routledge, 2022); Winkler and Schoeneborn (The research handbook of strategic communication. Edward Elgar, 2023)], this chapter examines how the municipality of Venice’s strateg
Rationale: A care bundle approach to the management of spontaneous intracerebral hemorrhage (ICH) has been shown to benefit patients in low- and middle-income countries (LMIC), but uncertainty persists over the specific components and its applicability in high-income countries (HICs). Aims: An international collaborative initiative aimed at determining whether implementation of a care bundle impro
Introduction: The Hippo signaling pathway is a key regulator of cellular growth and organ size, acting through the transcriptional coactivators YAP and TAZ. These proteins shuttle between the nucleus and cytoplasm in response to Hippo pathway activity, which, when active, leads to cytoplasmic sequestration and degradation of YAP/TAZ, preventing them from initiating gene transcription. Although ini
Objective: Antibiotic prophylaxis reduces infection risk following transrectal prostate biopsy. Studies in countries with high antibiotic resistance show that fosfomycin, given an hour or more before biopsy, has equal or better outcomes than ciprofloxacin. This study aimed to evaluate if fosfomycin, administered immediately before biopsy, is as effective as ciprofloxacin in Sweden, where antibioti
This paper introduces MNE-RT, a Python package designed for real-time neural feature extraction from magne-toencephalography (MEG) and electroencephalography (EEG) signals in Brain-Computer Interface (BCI) systems. The package incorporates efficient algorithms spanning traditional univariate metrics, such as frequency band power and entropy, to advanced bivariate connectivity measures. It is compa
This Registered Report examines urban-rural tensions in Sweden - a historically egalitarian, multi-party welfare state with strong geographical equalization schemes, making it a least-likely case for place-based resentment theories. Using an online survey experiment (n = 2,051), we measured resentment through perceptions of in-group and out-group, and by experimentally varying whether political st
In this article, I identify a key trend for demarcating the “secular” as a Western, Christian achievement. I analyze how the New Testament story often known as “Render unto Caesar” is referenced as a source for the secular West, particularly in writings by European and American conservative thinkers in the 1990s and early 2000s. My argument is that these references to “Render unto Caesar” constitu
Dyslipidemia is increasingly recognized as a potential driver of chronic kidney disease, independent of other components of the metabolic syndrome. This study aimed to investigate the direct impact of isolated dyslipidemia on kidney structure and function in dyslipidemic Psammomys obesus (P. obesus). P. obesus animals were fed either a low-energy diet (LED) or high-energy diet (HED) for 12 weeks.
