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Aeolian dynamics at the northern edge of Deliblato (Banat) Sand Sea, Vojvodina, Serbia, at the time of the last deglaciation

The Deliblato (Banat) Sand Sea, which is one of the largest areas of aeolian sand in Europe, is located near the Iron Gate, which marks the crossing of the Danube River through the biggest gorge of this river. Here, Danubian alluvium has served as the sand source for the Banat Sand Sea, which was formed primarily through southeasterly (Košava) winds. Utilizing a multi-proxy approach, the objective

Exploring predictive kinetic modelling of thermal degradation from laboratory to production scale – A case study on three vitamins in milk

Kinetic thermal degradation models are vital components for optimization of food and bioproducts processing. Typically, models are fitted to laboratory-scale experiments where vials are heated and held. However, these conditions are highly dissimilar from the thermal processes experienced in industrial production. Whereas fitting kinetic data to industrial-scale production is often impossible due

Experiences of managers and staff working in community-based mental health with people ageing with severe mental health problems

Background: Existing research shows that older people with severe mental health problems need different forms of support in daily life and in the community to lead an active and meaningful life. A common form of support for people with severe mental health problems in Sweden is attendance at community-based day centres (DCs). However, knowledge of staff and managers’ experiences of how people agei

Comparison of aluminum nitride thin films prepared by magnetron sputter epitaxy in nitrogen and ammonia atmosphere

Wurtzite-type aluminum nitride (AlN) thin films exhibiting high thermal conductivity, large grain size, and low surface roughness are desired for both bulk acoustic wave and surface acoustic wave resonators. In this work, we use ammonia (NH3) assisted reactive sputter deposition of AlN to significantly improve these properties. The study shows a systematic change in the structural, thermal, and mo

Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP), a common age-associated phenomenon, associates with increased risk of both hematological malignancy and cardiovascular disease. Although CHIP is known to increase the risk of myocardial infarction and heart failure, the influence of CHIP in cardiac arrhythmias, such as atrial fibrillation (AF), is less explored. METHODS: CHIP prev

X-ray standing-wave spectroscopy : A powerful method for probing buried interfaces

In this chapter we present a non-destructive method for characterizing buried interfaces with high depth resolution combining X-rays standing wave and photoemission electron spectroscopy. This method incorporates the power of the X-rays photoelectron spectroscopy, which is a surface sensitive technique in the nanometer and sub-nanometer regime, with the depth selectivity of X-ray standing wave. Th

Endosomal escape of RNA therapeutics

RNA therapeutics is a new class of targeted therapies that has entered the clinic in the last decade. Lipid nanoparticles (LNPs) and conjugation to N-acetylgalactosamine have proven to be efficient strategies to deliver RNA payload to the liver. Successful delivery of sensitive RNA molecules to other target tissues or tumors remains one of the key challenges with the development of new RNA-based t

Photon-counting computed tomography for paediatric congenital heart defects yields images of high diagnostic quality with low radiation doses at both 70 kV and 90 kV

Background: Photon-counting computed tomography (PCCT) is a new clinical method that may show better diagnostic quality at lower radiation doses than conventional CT. Objective: To investigate the diagnostic quality and radiation dose of paediatric cardiovascular PCCT for diagnosis of congenital heart defects at 70 kV and 90 kV. Materials and methods: This retrospective assessment included clinica

Reconciling East Asia's mid-Holocene temperature discrepancy through vegetation-climate feedback

The term “Holocene temperature conundrum” refers to the inconsistencies between proxy-based reconstructions and transient model simulations, and it challenges our understanding of global temperature evolution during the Holocene. Climate reconstructions indicate a cooling trend following the Holocene Thermal Maximum, while model simulations indicate a consistent warming trend due to ice-sheet retr

Machining SiC fibre reinforced metal matrix composites – How do different matrix materials affect the cutting performance?

SiC fibre reinforced metal matrix composites find widespread application but show major machining difficulties due to significant variations in constituents' properties. In this sense, while the SiC fibre plays significant strengthening effects, the properties mismatch between the brittle fibre and ductile matrix materials becomes important in their machining performance. Through machining tests,

Childhood Neighborhoods and Life-Time Fertility in Twentieth-Century Southern Sweden: A k-Nearest Neighbor Approach

Despite a large literature on the importance of childhood neighborhoods for life course transitions, there is a lack of fertility studies combining a life-course perspective with detailed neighborhood measures. Addressing this gap, we use longitudinal data in which the entire population of a Swedish town is geocoded at the address-level, 1939–1967, and linked to national registers from 1968 to 201

A simplified approach to prepare controlled cell adherence on biologically derived in vitro cell culture scaffolds by direct UV-mediated RGD linkage

In this work, we present a method to fabricate a hyaluronic acid (HA) hydrogel with spatially controlled cell-adhesion properties based on photo-polymerisation cross-linking and functionalization. The approach utilises the same reaction pathway for both steps meaning that it is user-friendly and allows for adaptation at any stage during the fabrication process. Moreover, the process does not requi

A practical guide to microfabrication and patterning of hydrogels for biomimetic cell culture scaffolds

This review article describes microfabrication techniques to define chemical, mechanical and structural patterns in hydrogels and how these can be used to prepare in vivo like, i.e. biomimetic, cell culture scaffolds. Hydrogels are attractive materials for 3D cell cultures as they provide ideal culture conditions and they are becoming more prominently used. Single material gels without any modific

Living in the Borderland : Young Migrant Converts in the Church of Sweden

From 2014 to 2016, 44,617 unaccompanied refugee minors (URMs) arrived in Sweden and sought asylum. The Church of Sweden has received hundreds of these young people seeking to join the church and be baptised as Christians. Conversion to Christianity among asylum seekers in Europe is a well-documented phenomenon that is often dismissed as merely a strategy to boost asylum chances. This dissertation

Decreased neutrophil function in newly diagnosed multiple myeloma patients is restored with lenalidomide therapy

OBJECTIVES: Bacterial infections are common and a major cause of morbidity and mortality in multiple myeloma (MM). We have investigated the function of polymorphonuclear leukocyte (PMN), the immune system's first line of defense against bacteria, in peripheral blood (PB) and bone marrow (BM) samples from patients with newly diagnosed MM (NDMM), smoldering MM (SMM), monoclonal gammopathy of undeter

Rättsutredning: strukturfondspartnerskapens konstitutionella ställning, jäv m.m.

Denna rättsutredning har tillkommit på uppdrag av Utredningen om hantering av EU-medel och ingår som en bilaga i utredningens slutbetänkande SOU 2024:22 (bilaga 4). Det övergripande temat är strukturfondspartnerskapens rättsliga status, men även ett antal andra frågor med relevans för utredningens arbete berörs, såsom jäv.

Exploring beta-mannan acting glycosidase families in hydrolysis and mannosyl transfer

The thesis revolves around the study of glycoside hydrolases (GH), specifically GH5 β-mannanases and GH36 α-galactosidase (I-III), as well as a GH130 mannoside phosphorylase (I, IV). These enzymes are investigated for their actions on and conversion of hemicellulosic β-mannan, including food-grade galactomannan and softwood galactoglucomannan, along with manno-oligosaccharides (MOS) derived from s