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Lymphomas are broadly categorized into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). Despite treatment advances, they remain a major cause of cancer-related morbidity and mortality in Canada. This study examined temporal trends in socioeconomic inequalities in lymphoma mortality in Canada from 2000 to 2019. Using a unique census division level dataset (n = 280) constructed by pooling infor
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Advances in ceramic additive manufacturing have enabled fabrication of piezoelectric metamaterials in which architecture can be used as a design parameter to expand and independently tune the different anisotropic electromechanical coupling modes. A critical step toward rational design of architected piezoceramics is the determination of complete piezoelectric tensor matrices for the differently o
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Strongly interacting fermions represent the key constituent of several intriguing phases of matter. However, due to the inherent complexity of these systems, important regimes are still inaccessible. Here, we derive a realistic and flexible setup based on ultracold magnetic lanthanide atoms trapped in a one-dimensional optical lattice. Leveraging their large magnetic moments, we design a fermionic
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Background. Ultra-High Dose Rate Radiotherapy (UHDR-RT) is an emerging cancer treatment that delivers radiation at dose rates exceeding 40 Gy/s. While UHDR-RT offers potential therapeutic benefits, accurate dosimetry presents significant challenges. Ionisation chambers, the standard for clinical dosimetry as reference and monitor dosimeters, experience significant ion recombination at high dose ra
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Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non-amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large-scale clinical trials, which typically focus on late-onset, sporadic amnestic-predominant AD. Consequently, treatment options and research ef
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Avocado farmworkers are potentially exposed to multiple pesticides, which may influence hematological parameters and detoxification enzyme activities. This study enrolled 105 avocado farmworkers from Michoacán, Mexico, during May–August 2021. We quantified 12 pesticide metabolites in urine samples collected at two visits (12–13 weeks apart) and estimated annual exposure intensity scores (EIS) usin
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mer-[CrCl3(THF)3] is a useful and labile precursor for Cr(III) organometallic chemistry, but the commercial material is costly and sometimes poorly defined, whereas existing synthetic routes to the complex rely on corrosive reagents, prolonged reaction times, or elaborate experimental setups which are impractical for glovebox work. Herein we present a facile, mild, and glovebox-friendly synthesis
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Background: Identification of breast cancer patients at high risk of relapse after neoadjuvant chemotherapy (NAC) is of high unmet clinical need. The multicenter ALIENOR study aimed to identify patients with molecular residual disease (MRD) using an ultrasensitive ctDNA assay during follow-up after NAC. Patients and methods: Patients whose tumor did not achieve pathologically documented complete r
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Artikel om anatomiundervisningen vid Lunds universitet med fokus på den varierande sociala och yrkesmässiga ställning som ur universitetsarkivets "likhandlingar" kan utläsas rörande de personer vars kroppar i äldre tid användes i denna undervisning, och hur dessa uppgifter kontrasterar mot den bild som 2010 framfördes i TV-programmet "Uppdrag granskning".
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Importance: Identifying individuals at higher risk of pancreatic cancer (PC) is critical for developing targeted prevention strategies. Objective: To investigate whether the potential association of modifiable risk factors with PC varies across genetic risk profiles and age. Design, Setting, and Participants: This prospective population-based cohort study used data from participants in the UK Biob
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The capacity to adapt to surprising conditions by quickly changing existing ways of working is essential for organizations operating in complex and unpredictable environments. Yet empirical understanding of factors contributing to adaptive capacity remains limited and fragmented. This paper presents findings from a qualitative case study of a sudden internal flooding at a Swedish hospital, based o
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Chronic pancreatitis is a progressive inflammatory disease associated with substantial nutritional and metabolic consequences. Beyond classical malnutrition, patients frequently develop alterations in body composition, particularly sarcopenia, which are increasingly recognised as clinically relevant but remain inconsistently assessed. The reported prevalence of sarcopenia ranges from 20% to 70%, i
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Background: Critical illness myopathy is a common and devastating consequence of critical care, causing dramatic loss of muscle mass and function in intensive care unit patients. Functional deficits often exceed the loss in muscle mass and myosin content. However, the mechanisms underlying the loss of force and emergence of myosin-expressing non-force-generating fibers remain elusive. Methods: Myo
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We model the flow behaviour of dense melts of flexible and semiflexible ring polymers in the presence of walls using a hybrid multiscale approach. Specifically, we perform molecular dynamics simulations and apply the Irving–Kirkwood formula to determine an averaged stress tensor for a macroscopic model. For the latter, we choose a Cahn–Hilliard–Navier–Stokes system with dynamic and no-slip boundar
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To verify the justification for an amendment of European Standard EN 14770:2023, this study investigates the effect of trimming on measured shear modulus and phase angle of bituminous binders using Dynamic Shear Rheometer (DSR). Six bituminous binders were analysed, including penetration grade neat bitumen and modified bitumen with polymer and wax. More than 400 DSR measurements (with trimming ver
