Sökresultat

Förståelse av dynamiken i interaktionen mellan proteiner och olika molekyler kan underlätta designen av nya läkemedel mot till exempel cancer. Detta kan man studera i stora magneter med så kallad magnetresonansspektroskopi. I kroppen finns en proteinfamilj, Galektiner, som deltar i många biologiska processer. Ett av dessa protein, Galektin-3, är involverat i utvecklingen av cancer vilket gör att This master thesis consists of two parts, which both deal with NMR studies of the carbohydrate-binding domain of the protein galectin-3 (Gal3C). In the first part, 19F relaxation of two difluorinated diastereomeric ligands bound to Gal3C was analyzed with the model-free approach to extract information about the dynamics. The second part reports the assignments of the backbone amide 1H/15N resonanc

The thesis explores efficient implementation strategies for the European Spallation Source (ESS) linear accelerator simulator. The target simulator needs to run at real time, requires high computation accuracy, and should be scalable for high density beam scenarios. The high data processing, communication, and storage requirements due to a large data set, along with a strict accuracy requirement,

Many locations in Indonesia such as small islands and remote villages on the main islands are not connected to the main electricity grid, and may never be as they are too remote for grid extensions to be economically justifiable. Therefore, many either do not have electricity or are dependent on expensive diesel transports to fuel their stand alone, diesel powered mini-grids. Using a hybrid renewaMany locations in Indonesia such as small islands and remote villages on the main islands are not connected to the main electricity grid, and may never be as they are too remote for grid extensions to be economically justifiable. Therefore, many either do not have electricity or are dependent on expensive diesel transports to fuel their stand alone, diesel powered mini-grids. Using a hybrid renewa

Jordbruksfåglar i områden med hög respektive låg andel vall Fåglar används ofta som indikatorer på miljöförändringar tack vare sin position högt upp i näringskedjan samt det faktum att de är lätta att studera. Fågelarter som förekommer och häckar i jordbrukslandskapet har minskat kraftigt i och med vårt moderna och intensiva jordbruk. Många studier påvisar hur olika faktorer som följer med det moMany bird species living in farmland habitats have suffered severe declines in recent years. This fact has been object to many studies and the reasons for the decline are many, but it all comes down to effects of our shift to a more effective farmland management. We use the land in a more intense way than before. The use of chemicals has effect both on the birds and their food resources. A more ho

Each year millions of people receive emergency relief items from humanitarian organizations following disasters and crises. While significant time and resources have been invested in identifying the needs of affected populations and how to address those needs, significantly less focus has been given to environmental impacts of these response operations. These impacts can result in substantial nega

The fashion industry is a significant contributor to global environmental and social issues. But as a system, it is composed of different stakeholders that can work together to make a change. One of those actors involved are small fashion labels, which according to the European Commission, account for more than 90% of the workforce and produce almost 60% of the value within the textile industry (2

Humanitarian organizations transitioning from a service provider (SP) to a capacity strengthener (CS) in countries where there is political stability and economic growth presents a set of opportunities and challenges. Despite this there has been limited research studies that have been conducted on the transition of humanitarian organizations in this context. The overall objective of this research

Begreppet genre är centralt inom musikvärlden och inom musikundervisning. Således är detta ett begrepp vi behöver förhålla oss till. Syftet med studien är att ta reda på vilken funktion genre har i sångundervisningen och hur begreppet kan behandlas. Genre har en tydlig plats i styrdokumenten för sång och instrumentalundervisningen på det estetiska programmet. Därför är detta en intervjustudie med Genre as an object of learning in vocal education - a study of vocal teachers’ view of genre and its function Musical genre as a concept is common and central in music and music education. Therefore, music teachers have to define and act to genre as a concept. The aim with this essay is to figure out which function genre has in the singing education and how genre can be managed. Since genre is a c

As interest in social vulnerability to hazards grows, more indices are formulated for identifying and mapping population groups that may experience differential consequences from natural hazards. However, less attention has been given to the underlying choices researchers make when creating these indices. With the aim to contribute to understanding the issues surrounding social vulnerability indic

Green areas in urban environments can have recreational, environmental and health benefits but for them to be utilized, high accessibility for inhabitants is necessary. In an expanding city like Gothenburg, maintaining geographic accessibility to green areas can be challenging. This study performs an accessibility analysis to assess whether Gothenburg has sufficient accessibility to green areas, a

Riskbaserad monitorering – ett sätt att säkerställa kvalitet i kliniska studier Kliniska studier undersöker effekter av medicinska behandlingar på människor. De är hårt reglerade för att säkerställa patientsäkerhet, det vill säga att försökspersonerna inte utsätts för onödiga hälsorisker, och för att säkerställa ett pålitligt studieresultat. Därför behöver alla processer och all data i varje studStudy quality is of paramount importance in clinical studies to ensure patient safety and reliable evaluation of the treatment, where the latter also entails the safety of future patients. Therefore, for example monitoring is required to minimise any risk of quality loss. Traditionally, the method for monitoring has been 100% source data verification which is costly and not sufficient. Today, auth

In this thesis, bootstrap percolation on a classic random graph

Ett par mil utanför Tallinn finns ett övergivet kalkbrott. Stenen i kalkbrottet bröts av fångar från de närliggande fängelserna som ligger innanför dubbla murar ovanför sjön som bildats när verksamheten lades ner och grundvattnet slutade pumpas ut i början av 1990-talet. Vattnet har stigit så att flera byggnader står helt eller delvis i vattnet. Fängelset och den kringliggande byn, Rummu, är byggEtt par mil utanför Tallinn finns ett övergivet kalkbrott. Stenen i kalkbrottet bröts av fångar från de närliggande fängelserna som ligger innanför dubbla murar ovanför sjön som bildats när verksamheten lades ner och grundvattnet slutade pumpas ut i början av 1990-talet. Vattnet har stigit så att flera byggnader står helt eller delvis i vattnet. Fängelset och den kringliggande byn, Rummu, är bygg

The growth of informal settlements especially in third world countries has become a problem on a global scale. In Asia and Africa, although under different circumstances, the fastest urbanization takes place. To find a good way on how to include the poor city migraters into the growing cities will be crucial in order to have more sustainable, peaceful and just societies. My focus lays on the semi-

The purpose of this thesis is to explore SMEs’ relations to stakeholders when implementing corporate social responsibility. Furthermore, it examines what role the size of the SMEs play in implementing CSR and in managing stakeholders. The thesis explores whether the competitive landscape of the market creates tension where SMEs’ decision makers feel pressured to choose between doing well financial

Processability Theory (PT) is a well-established theoretical framework within the field of Second Language Acquisition, which describes the development of acquiring language as a process of acquiring procedural skills. The procedural skills are necessary for the learner being able to process different grammatical structures of the target language, and these are obtained by the learner through avai

As online shopping continues to increase in popularity, more and more pressure is put on businesses to reevaluate which of their services that can be sold from a web- site. While the telecom market for businesses still only use expert salespersons to describe and put a price on their services, innovative companies such as Telavox are looking into new ways of exposing more of their information onli

The main purpose of this thesis is to explore how to deal with an industrial heritage in both urban and more detailed, architectural scale. The project location indicates another significant key issue - waterfront identity, which is essential for the city of Amsterdam. This thesis proposes a complex masterplan for the area, which provides diverse housing options, varied public spaces of different

Jamaica has struggled to curb the number of road crash fatalities, having had on average 25 fatalities per month between 2010 and 2014, while many more persons have been injured. The causes of crashes are multidimensional, however this study focused on understanding one aspect of reducing crashes - safe road design. The aim of this study was to determine the relationships between road design chara

In this thesis methods for finding state space representation parameters for low inductance DC-motors are found and evaluated. Theory previously tested in simulations is verified experimentally and improved upon for both linear behaviour when the motor is controlled with a DC-source as well as nonlinear behaviour when controlled with pulse width modulation (PWM). For the linear behaviour a linear