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Background: Sjögren’s disease (SjD) is an autoimmune condition affecting exocrine glands, resulting in decreased saliva and tear production. Aquaporin 5 (AQP5) is a transmembrane water channel playing a central role in water transport. In SjD, deregulation of AQP5 expression, trafficking and interactions with various proteins contribute to the underlying disease mechanisms. Methods: Co-immunopreci
Some vertebrates regenerate appendages through the action of small noncoding RNAs (smRNAs) expressed in their blastema. Inspired by these models, we investigated whether similar smRNA-mediated mechanisms might contribute to the intrinsic repair capacity of human cartilage. Although humans lack the capacity to regenerate entire limbs, digit tip regrowth and joint cartilage repair following joint di
Introduction: Amyloid- and tau-positron emission tomography (PET) are promising modalities for detecting pathological changes associated with Alzheimer’s disease (AD); however, their application is limited. Although the use of cerebrospinal fluid (CSF) biomarkers as alternatives to amyloid-PET and tau-PET has been explored, no in vitro diagnostic-approved or commercial CSF biomarker assays are cur
How is Turkish official memory negotiated locally in Izmir, a city celebrated as a symbol of national becoming, yet (im)famous for its scepticism of central power? How is the past of the city narrated, conceived as an epitome of progress, yet built on a systematic forgetting of trauma and violence? And how does the secularist legacy of Izmir, accentuated in contrast with the Islamisation of memory
Objective: The aim was to resuscitate and evaluate hearts ex vivo after 22 min of cardiac arrest with the goal of increasing the number of usable hearts from controlled donation after circulatory death (cDCD). Design: Eight pigs (39–61 kg) underwent 22 min of ventricular fibrillation, after which the heart was first perfused in vivo for three minutes with an oxygenated, erythrocyte-containing card
In landscapes shaped by intense agriculture, even common bee species may face limits to their dispersal capacity. We explored how spatial isolation and land-use types influence the genetic population structure of two generalist mining bees – Andrena haemorrhoa and A. nigroaenea – which differ in body size and putative dispersal potential, yet share similar ecological niches. Using a network of iso
On October 29 2023, Turkey celebrates the centenary of the Republic. We may anticipate this to be an equally spectacular and politicized event: a purported celebration of national unity, which in essence will reproduce and re-affirm distinct political wedges. Carefully choreographed national celebration has a long history in Turkey. And historiography has been its narrative bedrock, highlighting t
Objective: To estimate the probability of vaginal events (diagnosis and/or surgery) following radical cystectomy (RC) and explore possible risk factors in a nationwide population-based observational registry based study. Patients and Methods: Women undergoing RC for urinary bladder cancer in Sweden, from 1 January 1997 to 31 December 2019, were identified within national registries. Women with any
Nocturia, the urge to wake from sleep to void, is targeted sub-optimally by existing drugs that modulate circadian dysregulation of urine production in kidney without alleviating detrusor overactivity, a key aspect in the multifactorial etiology of nocturia. This study reports age-related upregulation of arginine vasopressin (AVP) synthesis in mouse urinary bladder to counter the concurrent declin
On 29 October 2023, Turkey will celebrate the centenary of the proclamation of the Republic. This promises to be a spectacular and carefully politized event, in line with earlier celebrations of National Days and other “defining moments” in the state’s autobiography (such as the conquest of Istanbul – celebrated in ever-aggrandising scale under the AKP-government). In official historiography, the
Despite its importance for the establishment of modern Turkey, İzmir remains understudied in scholarship on Turkish nationalism. This paper presents data from the project Beyond Sacred/Secular Cities, studying urban imaginaries in contemporary Middle Eastern nationalisms. With a point of departure in theories of memory (Connerton 1989), postsecularism (Asad 2018), and social construction of space
Objective: The Swedish national guidelines on penile cancer were first published in 2013. The objective of this study is to present the 2023 update of these guidelines and highlight the differences to the European Association of Urology (EAU) / American Association of Clinical Oncology (ASCO) guidelines on penile cancer. Material and methods: A review of the literature and a comparison to the EAU
Computational models of peritoneal dialysis (PD) are increasingly useful for optimizing treatment in patients with kidney disease requiring dialysis (KDRD). However, although several mathematical models have been developed in the past few decades, a direct comparison of the models’ accuracy with respect to predicting in vivo data is needed to further create robust personalized models. Here, we use
A Large Ion Collider Experiment (ALICE) has been conceived and constructed as a heavy-ion experiment at the LHC. During LHC Runs 1 and 2, it has produced a wide range of physics results using all collision systems available at the LHC. In order to best exploit new physics opportunities opening up with the upgraded LHC and new detector technologies, the experiment has undergone a major upgrade duri
Field reflections in an emergent genocide, Jerusalem October - December 2023
Genomgång av hur den nya musikformen jazz mottogs bland Lunds studenter speglat i bl a tidningen Lundagåd, i samtida dagspressnotiser om arrangemang i studentvärlden och genom bevarade dansprogram från studentikosa festligheter.
This article is devoted to analysing the design and symbolics of the Safra Square (Kikar Safra) and City Hall complex, Western Jerusalem. Built around the historic Town Hall of the British Governate, and inaugurated in 1993, the City Hall complex is strategically located along the bustling Jaffa Street, just west of the Green Line, andimmediately north of the Old City walls. This threshold locatio
This panel explores the political dynamics of memory and heritage-making in nationalist and counter-nationalist narratives in the contemporary Middle East. It explores how historical narratives are constructed by probing the rhetoric and aesthetics of both material and immaterial cultural heritage: from iconic personages, symbolic events and national myths to specific artifacts and museum displays
The 2022 centenary of the ‘liberation of Izmir’ saw no less than three municipally organised exhibitions thematising historic events long avoided in official memory: the Great Fire of 1922, and the ensuing Turkish-Greek population exchange. Incongruent with the tale of national triumph and unity, such disasters and displacements have been systematically repressed in Turkish official memory, brough
