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OBJECTIVE: To determine the effects of oxygen therapy in myocardial infarction (MI) patients with and without diabetes. RESEARCH DESIGN AND METHODS: In the Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) trial, 6,629 normoxemic patients with suspected MI were randomized to oxygen at 6 L/min for 6-12 h or ambient air. In this prespecified analysis involving
BACKGROUND: A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and diagnostic performance of a SiPM-based PET-CT (Discovery MI; GE Healthcare, Milwaukee, WI, USA) with a time-of-flight PET-CT scanner with a conventional PM detector (Gemini TF; P
Metastatic behavior varies significantly among breast cancers. Mechanisms explaining why the majority of breast cancer patients never develop metastatic outgrowth are largely lacking but could underlie the development of novel immunotherapeutic target molecules. Here we show interplay between nonmetastatic primary breast cancer and innate immune response, acting together to control metastatic prog
Importance: Preterm birth has been associated with cardiometabolic, respiratory, and neuropsychiatric disorders in adulthood. However, the prevalence of survival without any major comorbidities is unknown. Objective: To determine the prevalence of survival without major comorbidities in adulthood among persons born preterm vs full-term. Design, Setting, and Participants: National cohort study of a
BACKGROUND: Gout is the most common inflammatory arthritis with a rising prevalence around the globe. While educational inequalities in incidence and prevalence of gout have been reported, no previous study investigated educational inequality in mortality among people with gout. The aim of this study was to assess absolute and relative educational inequalities in all-cause and cause-specific morta
The limits of the environmental state in the context of the provision of economic growth are addressed by applying materialist state theory, state-rescaling approaches and the degrowth/postgrowth literature. I compare state roles in a capitalist growth economy and in a postgrowth economy geared towards bio-physical parameters such as matter and energy throughput and the provision of ‘sustainable w
The urban water crisis, including issues of water scarcity, pollution and flooding, is one of the key challenges for sustainable urban development. Reasons are manifold. Preventive measures are for instance being put on the back burner, while re-active measures and siloed governance are daily business, resulting in power struggles and ineffective governance. As the water crisis hits the most vulneWe are in the midst of a water crisis. Scarcity, pollution and flooding are some of today’s key challenges for sustainable urban development. The reasons are manifold. Preventive measures are put on the back burner, while reactive measures, siloed governance approaches and power struggles are daily business, resulting in ineffective governance. The crisis is hitting the most vulnerable urban popul
Antalet allvarliga konsekvenser av katastrofer i världen har ökat, vilket lett till ett internationellt initiativ för att främja utvecklingen av nationella strategier för katastrofriskreducering (DRR) och resiliens. Ett av de globala målen i Sendairamverket för katastrofriskreducering 2015-2030, antaget av FN:s medlemsstater, handlar om att länderna ska ta fram strategier kopplat till DRR (mål E).Increasing impacts from hazards worldwide, including Sweden, have prompted international efforts to promote the development of national strategies for disaster risk reduction (DRR) and resilience to reduce associated impacts and support sustainable development. The development of such strategies is global target E of the Sendai Framework for DRR 2015-2030, which was adopted in 2015 by Sweden and o
This chapter starts off in communication geography and discuss the dynamic relationship between media and place. The main argument is that processes of mediation are central to the meaning of place although without determination; mediations may both strengthen and weaken boundaries of place. This argument is based on an interdisciplinary double theorization where the concept of place as well as me
DN DEBATT 30/3. Översvämningar lyfts ofta som klimatfrågor eller som behov av skydd mot extrema väderhändelser. Då glöms andra viktiga orsaker bort, som hur vi använder marken och utvecklar bebyggelse. Tyvärr finns stora problem med styrningen av vattenhanteringen i dag, som bidrar till att skapa problem i stället för att förebygga dem, skriver åtta vattenexperter.
DebattTillgången till vatten kan inte längre ses som en lokal fråga utan måste ses ur ett bredare perspektiv, som kräver en samordning som är ny för Sverige. Det behövs sammanhängande nationell styrning och en strategi med helhetssyn på vattenfrågan, skriver nio svenska vattenexperter som kommer att debattera detta ämne under politikerveckan i Almedalen.
På senare år har flera studier visat på att järnhalten ökar i sjöar och vattendrag i norra Europa. Järn spelar en nyckelroll i akvatiska miljöer genom att påverka tillgängligheten av andra näringsämnen i vattnet så som kväve och fosfor, vilket kan reglera tillväxten av växtplankton. Dessutom färgar järn tillsammans med organiskt material vatten brunt. När vattnet blir brunare försämras ljusklimateIron (Fe) concentrations are increasing in freshwaters (lakes and streams) in Sweden, as well as in other regions in northern Europe. Together with increasing concentrations of organic matter, Fe is contributing to the ongoing browning of freshwaters, which may have serious ecological consequences and implications for ecosystem services. The aim of this thesis was to investigated where, to what ex
Från det vi föds är vi inställda på att lära. Vi iakttar människorna som omger oss och gör som de; vi lär oss tala, samspela, kommunicera. Vi lär genom att imitera. Drivkraften att lära genom efterbildning är något vi använder i retorikundervisningen; våra studenter utvecklar sina egna färdigheter i tal, skrift, läsning och lyssning genom att studera goda exempel och efterbilda dem. Principen kall
The message conveyed by the Intergovernmental Panel on Climate Change (IPCC) is clear: the global climate crisis has arrived (e.g., IPCC, 2007, 2014). It is commonly understood that responding to this crisis requires coordinated actions at a global level (Weischer et al., 2012, p. 117; Kulovesi, 2012, p. 193). Attempts to slow down the increase in global temperature, as well as to organize and exc
Popular Abstract in Swedish Polymerer är samlingsnamnet på långa molekylkedjor. Runt omkring oss i vårt dagliga liv är vi omgärdade av polymerer så som plaster, lim, fibrer och proteiner. Utvecklingen av många högteknologiska produkter är starkt beroende av polymera material. Grundläggande kunskaper om dem och deras egenskaper är därför viktigt. I ett batteri kan många fördelar erhållas då den koThere is a growing need for multifunctional polymeric materials for the development of several important energy conversion technologies. For example, the polymer electrolyte is a key component in lithium polymer batteries. The basic functions of this electrolyte are to efficiently conduct the lithium ions and physically separate the electrodes. Consequently, these electrolytes should ideally posse
This chapter describes the purification of rat liver plasma membranes by affinity partitioning in an aqueous polymer two-phase system using the lectin wheat germ agglutinin (WGA) as affinity ligand. Affinity partitioning is advantageous for conventional membrane fractionation techniques in being highly selective, allowing the rapid and high-yield purification of membranes. In addition, the aqueous
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