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Exploring Prospects for Agonistic Encounters in Conflict Zones : Investigating Dual Narrative Tourism in Israel/Palestine
This article contributes to the emerging literature on possibilities to disseminate agonistic narratives in seemingly deadlocked conflict settings. In this context, conflict parties’ existence is often perceived as being under threat, which makes it demanding to question the current societal order. However, even in the most protracted of conflicts, narratives exist that challenge concurring undersThis article contributes to the emerging literature on possibilities to disseminate agonistic narratives in seemingly deadlocked conflict settings. In this context, conflict parties’ existence is often perceived as being under threat, which makes it demanding to question the current societal order. However, even in the most protracted of conflicts, narratives exist that challenge concurring unders
Copeptin relates to a fatty liver and measures of obesity in a South African population with mixed ethnicities
Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri
Incidents resulting in health care among older people with intellectual disability in comparison with the general population : A national register study
Background: Older people with intellectual disability (ID) are at high risk of incidents leading to hospital visits. Method: Through national registers, 7936 people with ID, aged 55+ years in 2012, and a same-aged referent cohort from the general population were identified. Information on diagnoses made in inpatient and outpatient specialist health care during 2002–2012 was collected. Results: Com
Securing human rights through risk-management methods : Breakthrough or misalignment?
This is a study of three authoritative instruments that promote a common idea: economic activities and development should be conducted with respect for human rights. The World Bank Framework, the International Financial Corporation Performance Standards and the UN Guiding Principles on business and human rights are examined to get clarity on how human rights risk management differs from more conve
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Artikeln presenterar resultat från ett forskningsprojekt som studerade postmoderna, multikulturella och självbiografiska drag hos den spanske författaren Juan Goytisolo. Det visade sig att de personliga övertygelserna genomsyrade alla delar av författarens verk, men dessutom visade det sig att detsamma gällde ett antal kritiker, översättare och forskare som valt att skriva om författaren.
Cerebrospinal fluid concentrations of extracellular matrix proteins in Alzheimer's disease
Background: Brevican, neurocan, tenascin-C, and tenascin-R are extracellular matrix (ECM) proteins that are mainly expressed in the brain. They play important roles in proliferation and migration of neurons and other cell types in the brain. These ECM proteins may also be involved in various pathologies, including reactive gliosis. Objective: The aim of the study was to investigate if ECM protein
Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status
Importance: Accurate blood-based biomarkers for Alzheimer disease (AD) might improve the diagnostic accuracy in primary care, referrals to memory clinics, and screenings for AD trials. Objective: To examine the accuracy of plasma β-amyloid (Aβ) and tau measured using fully automated assays together with other blood-based biomarkers to detect cerebral Aβ. Design, Setting, and Participants: Two pros
RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS registry number 63500-71-0
2-Isobutyl-4-methyltetrahydro-2H-pyran-4-ol) was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol is not genotoxic, does not have skin sensitization potential, and provided an MOE >100 for the repeated dose,
RIFM fragrance ingredient safety assessment, 2,2,3-trimethylcyclopent-3-enylacetonitrile, CAS Registry Number 15373-31-6
Fostering improved human islet research : a European perspective
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
Alpha-synuclein (aSyn) accumulates in intracellular inclusions in synucleinopathies, but the molecular mechanisms leading to disease are unclear. We identify the 10 kDa heat shock protein (HSP10) as a mediator of aSyn-induced mitochondrial impairments in striatal synaptosomes. We find an age-associated increase in the cytosolic levels of HSP10, and a concomitant decrease in the mitochondrial level
Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition
Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estim
Technical design report for the PANDA Barrel DIRC detector
The PANDA (anti-Proton ANnihiliation at DArmstadt) experiment will be one of the four flagship experiments at the new international accelerator complex FAIR (Facility for Antiproton and Ion Research) in Darmstadt, Germany. PANDA will address fundamental questions of hadron physics and quantum chromodynamics using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c and a de
Stories of Resistance in Greek Street Art : A Cognitive-Semiotic Approach
In line with cognitive semiotics, this paper suggests a synthetic account of the important but controversial notion of narrative (in street art, and more generally): one that distinguishes between three levels: (a) narration, (b) underlying story, and (c) frame-setting. The narrative potential of street art has not yet been considerably studied in order to offer insights into how underlying storie
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
Background: Height and body mass index (BMI) are associated with higher ovarian cancer risk in the general population, but whether such associations exist among BRCA1/2 mutation carriers is unknown. Methods: We applied a Mendelian randomisation approach to examine height/BMI with ovarian cancer risk using the Consortium of Investigators for the Modifiers of BRCA1/2 (CIMBA) data set, comprising 14,
Transcatheter closure of atrial septal defect in adults : time-course of atrial and ventricular remodeling and effects on exercise capacity
Investigate ventricular and atrial remodeling following atrial septal defect (ASD) closure and examine if pulmonary-to-systemic flow ratio (QP/QS) and right ventricular (RV) volume predict improvement, determined as percentage of predicted oxygen uptake (VO2%). Long-term cardiovascular magnetic resonance (CMR) data on atrial and ventricular remodeling after ASD-closure is limited and treatment eff
Large-scale data-dependent kernel approximation
Learning a computationally efficient kernel from data is an important machine learning problem. The majority of kernels in the literature do not leverage the geometry of the data, and those that do are computationally infeasible for contemporary datasets. Recent advances in approximation techniques have expanded the applicability of the kernel methodology to scale linearly with the data size. Data
Affective Naturalization : Practices of Citizenship Conferment
In an era of increased mobility, naturalization is crucial for shaping international legal and political identities. It is therefore important to move beyond the legal definition of naturalization in order to comprehend its affective and social meaning. This article develops the notion “affective naturalization” by combining the literature of affect and politics with insights from economic anthrop
2HDME : Two-Higgs-Doublet Model Evolver
Two-Higgs-Doublet Model Evolver (2HDME) is a C++ program that provides the functionality to perform fast renormalization group equation running of the general, potentially CP-violating, 2 Higgs Doublet Model at 2-loop order. Simple tree-level calculations of masses; calculations of the oblique parameters S, T and U; different parameterizations of the scalar potential; tests of perturbativity, unit
