Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training and test set. We trained SSPs for subtypes and ROR assigned by nearest-centroid (NC) methods and SSPs

A conventional claim within tourism research, practice and policy is that tourism is a powerful engine for economic growth across all spatial scales, accounting for slightly more than 10 percent of the global number of jobs and gross domestic product (GDP). What does this tell us? First, that the tourism economy is heavily dependent on mobilising spatial, intangible, material and human resources.

In early breast cancer, a preoperative core-needle biopsy (CNB) is vital to confirm the malignancy of suspected lesions and for assessing the expression of treatment predictive and prognostic biomarkers in the tumor to choose the optimal treatments, emphasizing the importance of obtaining reliable results when biomarker status is assessed on a CNB specimen. This study aims to determine the concord

What if, in the encounter between the subject and the city, it is the buildings, the streets, the rooms that are moving and the human beings who are at a standstill? Inspired by the efforts of literary scholars and human geographers to apply a unified understanding of space and time to the study of the (fictional) city, this article employs an analysis centered on the figure of the elevator to exp

Introduction to themed cluster

There is a growing interest in industry and academia in machine learning (ML) testing. We believe that industry and academia need to learn together to produce rigorous and relevant knowledge. In this study, we initiate a collaboration between stakeholders from one case company, one research institute, and one university. To establish a common view of the problem domain, we applied an interactive r

Purpose: Low magnetic field systems provide an important opportunity to expand MRI to new and diverse clinical and research study populations. However, a fundamental limitation of low field strength systems is the reduced SNR compared to 1.5 or 3T, necessitating compromises in spatial resolution and imaging time. Most often, images are acquired with anisotropic voxels with low through-plane resolu

At the 2013 World Environmental and Water Resources Congress in Cincinnati, Ohio, the ASCE Task Committee on Research Databases for Water Distribution Systems was formed to develop an online open-access repository of water distribution system hydraulic network files for use in applied scientific research. This paper discusses the development of the resulting database, specific model contributions,

Crises are characterised by urgency and disorder, with the ordering practices of crisis management teams constituting key features of the response. In the Swedish refugee crisis that began in autumn 2015, numbers became a key analytic tool to comprehend,monitor and communicate the flow of people arriving in the south of the country. This study draws on theory from social studies of quantification,

Om bakgrunden och tillkomsten av LTH:s doktorsring, doktorshatt och LTH:s rektorskedja.

Historien om LTH:s, och TLTH:s, symbol Kvadraten-triangeln-cirkel och om senare tiders bruka av olika logotyper för LTH.

En genomgång av fiktiva språk, syldaviska, borduriska, Arumbya, i Hergés Tintin och om språkens rötter i den belgiska dialekten marolliska.