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Evaluating transformative policies in complex land-use systems

Policies that facilitate sustainability transformations require knowledge about the dynamics of complex socio-ecological systems, including biophysical mechanisms and diverse human-nature relationships. Such a comprehensive evidence base can only be built by integrating multiple types of knowledges. Ontology, epistemology, and semantics are a well-established terminology to structure and facilitat

Uncovering inequalities in greenspace access: an intersectional agenda for new sociological enquiry

Urbanisation, lifestyles and environmental degradation are associated with negative health and environmental outcomes through reducing greenspace access. These risks are not experienced equally across society. While useful concepts like ‘extinction of experience’ exist, sociological writing on these important themes remains underdeveloped. Using regression and analysis of variance with survey data

Swedish consumers’ perspectives on wild bilberries : Attitudes, associations, consumption patterns, and foraging behaviour

Efforts to develop the wild berry industry in Sweden and internationally call for increased knowledge about the consumer perspective. Our objective is to investigate attitudes, product associations, consumption patterns, and foraging behaviour regarding bilberries, with an online survey using a nationally representative sample (N = 2010). The data were analysed with regression and multinomial test

Maintenance olaparib monotherapy in patients with platinum-sensitive relapsed ovarian cancer without a germline BRCA1 and/or BRCA2 mutation : Final overall survival results from the OPINION trial

Objective: Maintenance olaparib demonstrated clinical activity for progression-free survival in patients without a germline BRCA1 and/or BRCA2 mutation (non-gBRCAm) who had platinum-sensitive relapsed ovarian cancer in the phase IIIb, open-label, single-arm, non-comparator, international OPINION trial (NCT03402841). We report final overall survival (OS; secondary endpoint), prespecified secondary

Twenty Years of the Paediatric Radiation Oncology Society

In 2005, the Paediatric Radiation Oncology Society (PROS), a multi-professional association to promote radiotherapy for children and young people, was created. Its mission has been to educate those involved in this field, and to improve the standards of radiation oncology care for children, adolescents, and young adults across the globe, not least in less privileged settings where the majority of

Laser applications to chemical, security, and environmental analysis : introduction to the feature issue

The 19th Topical Meeting on Laser Applications to Chemical, Security, and Environmental Analysis (LACSEA) was held in Toulouse, France from 15–19 July 2024, as part of the Optica Optical Sensing Congress, with a return to in-person attendance. The meeting featured 21 sessions covering recent advances in laser and optical spectroscopy, sensor design, and diagnostic application. A total of 125 contr

Health Technologies and Impermissible Delays : The Case of Digital Breast Tomosynthesis

This paper argues that we have a moral obligation to implement certain health technologies even if we have limited or incomplete evidence of their effectiveness. The focus is on technologies used in non-emergency settings, as opposed to “exceptional cases” such as compassionate use and emergency approvals during public health emergencies. A broadly plausible moral principle – the Ecumenical Princi

Lipoprotein(a), Cholesterol, Triglyceride Levels, and Vulnerable Coronary Plaques : A PROSPECT II Substudy

Background: Although lipoprotein(a) (Lp[a]) has been associated with acute myocardial infarction (MI), the relationship between Lp(a) and the presence of high-risk “vulnerable” coronary plaques has not been studied. Objectives: The aim of this study was to investigate whether specific lipoproteins are associated with pancoronary plaque volume and lipid deposition vs the development of non-flow-lim

Arterial and venous thrombosis in systemic and monogenic vasculitis

Systemic vasculitis, common forms of which include anti-neutrophil cytoplasmic antibody-associated small-vessel vasculitis, large-vessel vasculitis and Behçet syndrome, are frequently complicated by arterial or venous thrombotic events (AVTEs). Newly identified entities such as DADA2 (deficiency of adenosine deaminase 2) and VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome

Enhancing Core Loss Tracking Accuracy in Stator Cores : A Comparative Assessment of Static and Dynamic Jiles-Atherton Model Formulations

In this paper a comparison between static and dynamic formulations of the Jiles-Atherton (JA) hysteresis model is presented. An assessment on the accuracy of core loss prediction and hysteretic loops reproduction of experimentally characterized on stator cores is performed. The novelty in this work is found in the optimized JA parameter datasets describing all the hysteresis loop measured for each

The Swedish Society of Paediatric Infectious Diseases' 2025 Recommendations for the Initial Management of Suspected Paediatric Sepsis With or Without Shock

The Swedish Society of Paediatric Infectious Diseases worked with paediatric societies for emergency medicine, anaesthesia, and intensive care to produce the 2025 recommendations for the initial management of suspected sepsis. They cover 28 days of corrected age to 18 years, but exclude immunodeficiency, immunosuppression, and suspected meningitis. Suspicion of sepsis and sepsis-associated shock i

Stratification of insect diversity and daily activity patterns in the West African virgin forest Taï assessed by entomological Lidar

Lidar technology was utilized to non-destructively explore the diverse insect life in the Taï virgin forest of Côte d'Ivoire. This study employed an entomological Lidar scanned at different elevation angles, combined with traditional insect trapping at different canopy heights, to investigate the composition and spatial-temporal distribution of insects within the forest canopy. We detected stratif

Proteomic Profiling of Acoustically Isolated Extracellular Vesicles from Blood Plasma during Murine Bacterial Sepsis

Sepsis is a life-threatening condition caused by a dysregulated host response to an infection and is a leading cause of death worldwide. The condition is variable, which in combination with insufficient clinical markers, makes it challenging to predict when infection will progress to sepsis and to categorize patients into homogeneous patient subgroups. In this study, we demonstrate the use of acou

Autoantibodies as prognostic markers in rheumatoid arthritis

Background and purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by progressively destructive polyarthritis. Key autoimmune features include the presence of autoantibodies. The purpose of this review is to discuss the diagnostic and prognostic properties of rheumatoid factor (RF) and anti-citrullinated protein/peptide antibodies (ACPA), based on current use in Swe

Relatedness, complexity, and regional development paths in Germany : a sequencing approach

This paper critiques the implementation of the EU's Smart Specialization Strategies (S3), advocating for a deeper analysis of the long-term evolution of regional industrial portfolios. We investigate the changing coherence of these portfolios across 401 German NUTS-3 regions from 1993 to 2018, utilizing skill- and task-based metrics for relatedness and complexity, alongside sequence analysis and o

Does colour-morph variation in metabolic physiology and oxidative stress match morph-specific life–history strategies?

Understanding to what extent phenotypes vary in their physiological traits and their associations to life-history strategies may help to better understand how animals are adapted to their environment and how they can cope with changing conditions. Melanin-based colour polymorphism is a phenotypic trait closely associated with physiological characteristics and fitness, which in tawny owls (Strix al

Influenced by others : Trusting behaviour and social influence

This paper reports results from a trust game in which trustors, before deciding on their transfer, are shown a statement about the perception of the situation by another person. Statements expressed either suspicion, insecurity, worry of disappointment or curiosity. Trustors first had to indicate their identification with the statement before making trust game decisions. Compared to a standard tru