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As our knowledge of diseases and the development of new technologies increases,many health problems that were lethal in the past can now be cured. Couple thisto better life quality and improved medical care, we are seeing an increase in theaverage life expectancy. The downside to this, however, is that diseases that developwith age are becoming more common. There is currently an estimated 47 milliCerebral senile plaque is one of the main pathologies of Alzheimer's disease (AD). The amyloid cascade hypothesis suggests that the aggregation of amyloid beta (Abeta) peptide is involved in the pathogenesis of AD, which is supported by the fact that Abeta overexpression or production of more aggregation-prone variants lead to early-onset dementia. In this work, we mainly studied the in vitro Abet

Patients with suspected disease involving the liver and seen at a department for infectious diseases were examined routinely for Au-antigen. Of 344 patients examined, 259 were found to have biochemical evidence of liver affection. Acute hepatitis was diagnosed in 129, including 65 with serum hepatitis, 18 with infections hepatitis and 46 with sporadic hepatitis. 62 patients had Au-antigen and 60 o

A trade-off between survival to sexual maturity and mating success is common across alternative reproductive tactics (ARTs), and can lead to tactical disruptive selection on shared traits (i.e. positive selection gradient in one tactic, and negative selection gradient in another). We were interested in examining the theoretical possibility of tactical disruptive selection on intrinsic growth rate.

Next-generation sequencing methods have revolutionized the speed of generating variation information. Sequence data have a plethora of applications and will increasingly be used for disease diagnosis. Interpretation of the identified variants is usually not possible with experimental methods. This has caused a bottleneck that many computational methods aim at addressing. Fast and efficient methods

Purpose: To study the phenotype in two families with genetically identified autosomal dominant retinitis pigmentosa (adRP) focusing on macular structure and function. Methods: Clinical data were collected at the Department of Ophthalmology, Lund University, Sweden, for affected and unaffected family members from two pedigrees with adRP. Examinations included optical coherence tomography (OCT), ful

To achieve cleaner combustion and higher efficiency in compression ignition (CI) engines, many new combustion strategies have been developed. Among these new concepts, partially premixed combustion (PPC) attracts a lot of attention, because of its possibility to achieve simultaneously low soot and NOx. Compared to homogeneous charge compression ignition (HCCI) combustion, charge stratification in

Women-focused development initiatives have become a controversial issue connected with women's health and welfare. Previous studies indicated that development initiatives might increase women's workload, family conflict, and marital violence. This study explored the gendered characteristics of a development initiative Rural Mother Center in Bangladesh. Data incorporated policy document and intervi

Background: In Europe, residential care homes (RCHs) are replacing hospitals as the place where death occurs, and they play an important role in end-of-life (EOL) care. Objective: The aim was to describe the quality of care during the last 3 months and last 3 days of life of those who died in RCHs as reported by family members. We also investigated whether there were differences in the EOL care of

Pneumococci isolated from the ear exudate in 245 children under 10 years of age afflicted with acute otitis media were typed. Types 3, 6, 14, 18, 19 and 23 were found in 80% of the cases. In the remaining cases, 15 other types were found. Five strains were not typable with the antisera used. Types 14 and 23 were found twice as often in the age group 0-3 years as in the higher age groups, whereas t

Optothermal spectrometry measures the thermal energy produced as a result of absorption by molecules at a given modulation frequency and wavelength. Depending on the modulation frequency used, analysis can be performed in very thin layers (50—150 micrometers). A major advantage of optothermal spectrometry is that it is not very sensitive to light scattering. Haemoglobin in whole blood was measured