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About 7000 concrete bridges in Sweden were built before 1965. The annual cost for maintenance of these bridges is about 0.6% of their total value. The cooling water tunnels at Swedish nuclear power plants have been exposed to seawater for about 30-40 years. The maintenance cost for these tunnels has been evaluated to be about one billion Swedish kronor. It is important to evaluate the risk of corr
Background: Fruit and vegetable consumption might prevent weight gain through their low energy density and high dietary fiber content. Objective: We assessed the association between the baseline consumption of fruit and vegetables and weight change in participants from 10 European countries participating in the European Prospective Investigation into Cancer and Nutrition study. Design: Diet was as
Geological data on the Precambrian basic complexes of the Siberian Craton and their isotopic age are considered. The three main episodes of Precambrian basic magmatism of Siberia correspond to certain stages of the geodynamic evolution of the craton and the Earth as a whole. In the Late Paleoproterozoic, largely in the south and the north of the craton, the basic rocks were emplaced against the ba
The first step of aquifer parameter and dependent variable estimation based on hydraulic modeling is generally to choose the best steady-state condition for the set time period. In order to define the best estimated hydraulic conductivity and boundary condition for Gareh-Bygone Plain in arid southern Iran, ten different steady-state conditions were simulated and calibrated with limited field obser
Measuring pilot mental workload can be important for understanding cognitive demands during flight involving unusual movements and attitudes. Data on heart rate, eye movements, EEG, and subjective ratings from 7 flight instructors were collected for a flight including a repeated aerobatics sequence. Heart rate data and subjective ratings showed that aerobatic sequences produced the highest levels
The overall aims of this work were to investigate if Deep Brain Stimulation in the subthalamic nuclei (STN) affected balance, fear of falling and falls in people with Parkinson's disease. The effect of STN stimulation alone was investigated in Papers I, II and III. The participants were evaluated after an overnight withdrawal of anti-PD medication and with the STN stimulation turned off and on. F
Inappropriate surface expression of voltage-gated Ca(2+)channels (CaV) in pancreatic ß-cells may contribute to the development of type 2 diabetes. First, failure to increase intracellular Ca(2+) concentrations at the sites of exocytosis impedes insulin release. Furthermore, excessive Ca(2+) influx may trigger cytotoxic effects. The regulation of surface expression of CaV channels in the pancreatic
Popular Abstract in Swedish Resultatet efter en höftprotesoperation är otvetydigt gott med smärtfrihet och god funktion ofta livet ut hos de flesta. 2012 opererades i Sverige cirka 16000 patienter med höftprotes och siffran stiger. 3-4% av patienterna drabbas av en proteslossning under de första tio åren och behöver opereras om, en så kallad revision. Den gamla protesen avlägsnas då och ersätts meThe clinical success of primary hip replacement is paramount but the need for revisions will continue to increase due to the increasing number of operated individuals. In Sweden, the number of hip revisions in 2012 exceeded 2,300. During implant loosening, some of the bone in the femur is lost, which can make the revision more difficult. One way of handling bone loss has been the impaction techniq
Free radical polymerization of DMAAm (dimethylacrylamide)-co-PEG diacrylate in a semi-frozen aqueous solution was studied using H-1 NMR, which enables to monitor the non-frozen water as well as the reaction of monomers over time. It was possible to confirm the presence of a heterogeneous system with a liquid phase where the monomers were concentrated and the reaction proceeded. The resulting macro
Hexokinase 2 (Hxk2p) from Saccharomyces cerevisiae is a bi-functional enzyme being both a catalyst and an important regulator in the glucose repression signal. In the presence of xylose Hxk2p is irreversibly inactivated through an autophosphorylation mechanism, affecting all functions. Consequently, the regulation of genes involved in sugar transport and fermentative metabolism is impaired. The ai
In manipulation tasks, motion trajectories are characterized by a set of key phases (i.e., motion primitives). It is therefore important to learn the motion primitives embedded in such tasks from a complete demonstration. In this paper, we propose a core framework that autonomously segments motion trajectories to support the learning of motion primitives. For this purpose, a set of segmentation po
To identify the atomic number of superheavy nuclei produced in Ca-48-induced fusion-evaporation reactions, an experiment aiming at measuring characteristic X-rays is being prepared at GSI, Darmstadt, Germany. The gas-filled separator TASCA will be employed, sending the residues towards the multi-coincidence detector setup TASISpec. Two ion-optical modes relying on differing magnetic polarities of
Although contentious, the concept of resilience is common in sustainability research. Critique of the concept have often focused on the content of the concept. In this paper we focus on another feature of concepts, namely how they are defined. We distinguish between concepts that are ostensively defined, that aim to point to some phenomena, and stipulatively defined concepts, where the content of
For some Banach spaces of analytic functions in the unit disk (weighted Bergman spaces, Bloch space, Dirichlet-type spaces), the isometric pointwise multipliers are found to be unimodular constants. As a consequence, it is shown that none of those spaces have isometric zero-divisors. Isometric coefficient multipliers are also investigated.
Background. Expression of the peptide hormones ghrelin and obestatin has previously been demonstrated in human mammary glands. However, the clinical implications of the expression of these peptides in breast cancer are unclear. The aim of this study was to investigate the potential clinical value of ghrelin and obestatin as breast cancer biomarkers. Methods. A tissue microarray containing breast c
Using transgenic mouse models of breast cancer that ablate Src homology and collagen A ( ShcA) expression or oncogene-coupled ShcA signaling, we previously showed that this adaptor is critical for mammary tumor onset and progression. We now provide the first evidence that ShcA regulates mammary tumorigenesis, in part, through its ability to regulate the adaptive immune response. Inactivation of Sh
