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Antibody-guided identification of Achromobacter xylosoxidans protein antigens in cystic fibrosis.

Persistent bacterial airway infection is a hallmark feature of cystic fibrosis (CF). Achromobacter spp. are gram-negative rods that can cause persistent airway infection in people with CF (pwCF), but the knowledge of host immune responses to these bacteria is limited. The aim of this study was to investigate if patients develop antibodies against Achromobacter xylosoxidans, the most common Achromo

Frequency of haematogenous periprosthetic joint infection due to bacteraemia caused by gram-positive cocci

BackgroundPresence of a prosthetic joint entails a life-long risk of haematogenous periprosthetic joint infection (hPJI) during bacteraemia. For bacteraemia with Staphylococcus aureus the hPJI frequency has been described to be up to 40% and for streptococci up to 20%, with large variation among reported frequencies.ObjectivesWe aimed to investigate the hPJI frequency from bacteraemia with virulen

Current noise in quantum dot thermoelectric engines

We theoretically investigate a thermoelectric heat engine based on a single-level quantum dot, calculating average quantities such as current, heat current, output power, and efficiency, as well as fluctuations (noise). Our theory is based on a diagrammatic expansion of the memory kernel together with counting statistics, and we investigate the effects of strong interactions and next-to-leading or

XeroGraph: enhancing data integrity in the presence of missing values with statistical and predictive analysis

MOTIVATION: Missing data present a pervasive challenge in data analysis, potentially biasing outcomes and undermining conclusions if not addressed properly. Missing data are commonly classified into Missing Completely at Random (MCAR), Missing at Random (MAR), and Missing Not at Random (MNAR). While MCAR poses a minimal risk of data distortion, both MAR and MNAR can seriously affect the results of

Practical synthesis of an [8]annulene-based hydrocarbon with a projected actuator function

Känslan av mobilskärmen mot fingertoppen, klickljuden från kollegan som knappar på tangentbordet, skenet från en färgglad televisionsskärm som lyser upp vardagsrummets dunkel ... Den moderna människans tillvaro präglas av hens samspel med informationshanterande elektronik, och förbättringar inom informationsteknik är därmed av stor betydelse för en högre levnadsstandard. Ett sätt att förbättra kom[8]annulene units linked by alternating benzo[a,e]moieties are a promising new design for electro-responsive hydrocarbons. However, current methods for synthesizing benzo[8]annulenes limit the prospect of constructing longer multimers. In this work, an alternative synthesis route to the compound containing two [8]annulene moieties was pursued. The dimeric compound was ultimately furnished over thr

An asymmetric fission island driven by shell effects in light fragments

Nuclear fission leads to the splitting of a nucleus into two fragments1,2. Studying the distribution of the masses and charges of the fragments is essential for establishing the fission mechanisms and refining the theoretical models3,4. It has value for our understanding of r-process nucleosynthesis5,6, in which the fission of nuclei with extreme neutron-to-proton ratios is pivotal for determining

Lärostycken

Vem är den unge kamraten? Vad finns kvar av det som en gång var en rörelse? Vad hände med alla storslagna drömmar om att förändra världen? Vad gör vi om vi redan förlorat och våra fiender sitter vid makten? Med föreställningarna Våld & pedagogik och Kropp & straff ville dramatikern Henrik Bromander och regissören John Hanse skapa nya lärostycken som tog sikte på samtidens akuta frågor. Ins

Hierarchical event segmentation of episodic memory in virtual reality

Contextual shifts are crucial for episodic memory, setting event boundaries during event segmentation. While lab research provides insights, it often lacks the complexity of real-world experiences. We addressed this gap by examining perceptual and conceptual boundaries using virtual reality (VR). Participants acted as salespeople, interacting with customers in a VR environment. Spatial boundaries

Remembering the past affects new learning : The temporal dynamics of integrative encoding

Memories link elements across event boundaries, integrating overlapping content experienced at different times and places. Such memory representations are thought to rely on memory integration mechanisms. The present study used multivariate pattern analysis (MVPA) of electroencephalographic (EEG) data to elucidate the temporal dynamics of integrative encoding memory processes. Memory integration w

Investigating the relationship between musical development and social inclusion in Swedish instrumental small-group teaching

Swedish art and music schools (SAMS), established in the 1940s, aim to provide affordable extra-curricular instrumental and singing education for all children, regardless of their parents’ economic situation. The tuition is highly subsidized, with families contributing only about 7% of the tuition costs. While traditionally focusing on one-to-one instruction, a recent governmental report (2016) ha

Time-resolved representational similarity analysis reveals integrated and separated neural patterns of overlapping events

Episodic memory allows the flexible retrieval of commonalities and idiosyncrasies of overlapping life events. For example, seeing a woman in the city with your colleague's daughter may form an integrated memory representation involving the woman and your colleague. However, you may also keep a specific representation of the city event to talk with your colleague about the circumstances of having m

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Reading An Yu’s Poetry (Preface)