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Botulinum neurotoxins (BoNTs) are the causative agents of a potentially lethal paralytic disease targeting cholinergic nerve terminals. Multiple BoNT serotypes exist, with types A, B and E being the main cause of human botulism. Their extreme toxicity has been exploited for cosmetic and therapeutic uses to treat a wide range of neuromuscular disorders. Although naturally occurring BoNT types share
This article is focused on the appeal of far-right populist politics in the everyday and how this appeal is related to continuity and change in the global order. Contemporary societies have witnessed an upsurge of populist movements and groups set on filling a political space by appealing to a population in search of solutions to an ever-changing political and economic landscape. Here, we specific
The climate crisis is an unprecedented existential threat that causes disturbing emotions, such as anxiety. Recently, Clayton and Karazsia measured climate anxiety as “a more clinically significant ‘anxious’ response to climate change” (2020, p. 9). To gain a more nuanced understanding of the phenomenon from an empirical psychological perspective, we translated the core of the Climate Anxiety Scal
The generalized sparse iterative covariance-based estimation ( $q$ -SPICE) algorithm was recently introduced for scanning radar applications, resulting in substantial improvements in the angular resolution and quality of the processed images. Regrettably, the computational complexity and storage cost are high and quickly increase with growing data size, limiting the applicability of the estimator.
Time-varying spatially coupled low-density parity-check (SC-LDPC) codes with very large period are characterized by significantly better error rate performance and girth properties than their time-invariant counterparts, but the number of parameters they require to be described is usually very large and unpractical. Time-invariant SC-LDPC codes, which can be seen as periodically time-varying codes
Modern high-voltage high-power pulsed modulators typically generate pulses by discharging energy stored in one or more capacitor banks into the load. The capacitor discharge manifests itself as output pulse droop which must be compensated for. To eliminate such droop, modulators utilizing pulse transformers require external circuitry and, typically, passive resonant bouncer circuits are used. For
ACN-Sim is a data-driven, open-source simulation environment designed to accelerate research in the field of smart electric vehicle (EV) charging. It fills the need in this community for a widely available, realistic simulation environment in which researchers can evaluate algorithms and test assumptions. ACN-Sim provides a modular, extensible architecture, which models the complexity of real char
Simultaneous localization and communication (SLAC) is a desirable feature of 5G and beyond 5G wireless networks. To be able to implement SLAC, efficient high dimensional channel estimation methods are critical. This work presents a low-complexity multidimensional channel parameter estimation via rotational invariance techniques (MD-ESPRIT). We use both the spatial smoothing and forward-backward av
Computational methods to understand interactions in bio-complex systems are however limited to time-scales typically much shorter than in Nature. For example, on the nanoscale level, interactions between nanoparticles (NPs)/molecules/peptides and membranes are central in complex biomolecular processes such as membrane-coated NPs or cellular uptake. This can be remedied by the application of e.g. J
The contributions from anions and cations from salt are inseparable in their perturbation of molecular systems by experimental and computational methods, rendering it difficult to dissect the effects exerted by the anions and cations individually. Here we investigate the solvation of a small molecule, caffeine, and its perturbation by monovalent salts from various parts of the Hofmeister series. U
Despite urgent need for climate action, denial of climate change and resulting absence of appropriate pro-environmental behavior are widespread. Interpretive (recognition of climate change as a problem but re-interpretation of its severity) and implicatory denial of climate change (recognition of climate change as a problem but denial of psychological, political, and moral implications) can be int
