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European Society for Organ Transplantation (ESOT) Consensus Statement on Outcome Measures in Liver Transplantation According to Value-Based Health Care

Liver transplantation is a highly complex, life-saving, treatment for many patients with advanced liver disease. Liver transplantation requires multidisciplinary teams, system-wide adaptations and significant investment, as well as being an expensive treatment. Several metrics have been proposed to monitor processes and outcomes, however these lack patient focus and do not capture all aspects of t

Are enhanced recovery protocols after pancreatoduodenectomy still efficient when applied in elderly patients? A systematic review and individual patient data meta-analysis

Background: This meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared to conventional care on postoperative outcomes in patients aged 70 years or older undergoing pancreatoduodenectomy (PD). Methods: Five databases were systematically searched. Comparative studies with available individual patient data (IPD) were included. The main outcomes were posto

Efficient Data Processing for Coded Aperture Snapshot Spectral Imager Systems

Snapshot Spectral Imaging enables the acquisition of hyperspectral images (HSI) from 2D projected measurements employing specialized optical systems, such as the Coded Aperture Snapshot Spectral Imager (CASSI). Specifically, the CASSI system performs spatio-spectral codification of light obtaining 2D projected measurements. These measurements are then processed by algorithms to obtain the desired

Comparable survival in rats with intracranial glioblastoma irradiated with single-fraction conventional radiotherapy or FLASH radiotherapy

Background: Radiotherapy increases survival in patients with glioblastoma. However, the prescribed dose is limited by unwanted side effects on normal tissue. Previous experimental studies have shown that FLASH radiotherapy (FLASH-RT) can reduce these side effects. Still, it is important to establish an equal anti-tumor efficacy comparing FLASH-RT to conventional radiotherapy (CONV-RT). Methods: Fu

Impact of thermal processing on micronutrients and physical stability of milk and cream at dairy production scale

Micronutrients and physical stability of milk and cream were evaluated for different heat treatments at dairy production scale (HTST pasteurisation, high pasteurisation, ESL indirect and UHT direct and indirect). Changes caused due to heat treatments for macro and micro components (vitamins and minerals) as well as physical stability were investigated. Results show limited losses in macro componen

Microscopic theory of current-induced skyrmion transport and its application in disordered spin textures

Introduction: Magnetic skyrmions hold great promise for realizing compact and stable memory devices that can be manipulated at very low energy costs via electronic current densities. Methods: In this work, we extend a recently introduced method to describe classical skyrmion textures coupled to dynamical itinerant electrons. In this scheme, the electron dynamics is described via nonequilibrium Gre

Regional eco-innovation trajectories

Given that eco-innovations and the associated renewal of regional economic structures are pivotal in addressing environmental challenges, regional research is increasingly focusing on their spatio-temporal dynamics. While green technological and industrial path developments in specific regions have received considerable attention, little effort has been made to derive general patterns of environme

A Robust Observer with Gyroscopic Bias Correction for Rotational Dynamics

We propose an observer for rotational dynamics subject to directional and gyroscopic measurements, which simultaneously estimates the gyroscopic biases and attitude rates. We show uniform almost global asymptotic and local exponential stability of the resulting error dynamics, implying robustness against bounded disturbances. This robustness is quantified with respect to a popular nonlinear comple

The role of substance use disorders in the transition from suicide attempt to suicide death : a record linkage study of a Swedish cohort

BACKGROUND: Suicidal behavior and substance use disorders (SUDs) are important public health concerns. Prior suicide attempts and SUDs are two of the most consistent predictors of suicide death, and clarifying the role of SUDs in the transition from suicide attempt to suicide death could inform prevention efforts. METHODS: We used national Swedish registry data to identify individuals born 1960-19

Quantitative assessment of cleft volume and evaluation of cleft’s impact on adjacent anatomical structures using CBCT imaging

Objectives: To determine pre-operative cleft volume and evaluate cleft´s impact on surrounding anatomical structures in children and adolescents with orofacial clefts using cone bean computed tomography (CBCT) imaging. Methods: The present retrospective study retrieved CBCT examinations of 68 patients from a previous study. The examinations had been exposed either before (n = 53) or after (n = 15)

Transporthistoriska underlag till nytta för infrastruktur och forskning : en förstudie

Rapporten är resultatet av ett tvåårigt samarbetsprojekt mellan Centrum för Näringslivshistoria och Statens maritima och transporthistoriska museer, finansierat av Trafikverkets FoI-medel. Förstudien syftar till att undersöka de väg-, civilflygs- och järnvägshistoriska samlingarnas potential som källa till historisk och annan forskning och som resurs i Trafikverkets planering och verksamhet. Målsä

Planeringsverktyg för Bus rapid Transit (BRT) i Sverige

Rapporten presenterar ett uppdaterad planeringsverktyg för Bus Rapid Transit (BRT), anpassat för en svensk kontext. Planeringsverktyget är tänkt att fungera som ett samverkansstöd för planerare och består av 25 olika parametrar fördelat på 4 olika kategorier; Stadens utformning, Kollektivtrafikens infrastruktur, Fordon och stödsystem samt Trafikering.

Empowered and engaged : Group exercise for adolescent depression – perspectives from adolescents, parents and healthcare professionals

Objectives: Depression is increasing and is a leading cause of disease burden among adolescents. Available evidence-based treatments with medication or psychotherapy have modest effects. Aerobic exercise is a hopeful alternative as an augmenter or a stand-alone treatment. Qualitative studies have shown that participants in group exercise for adolescent depression experienced improved mood and a se

Exploring the potential of rock surface luminescence from glacial sediments : dating and transport history

The dating of moraine deposits can present challenges to standard geochronological methods; terrestrial cosmogenic nuclide (TCN), sediment luminescence and radiocarbon dating may suffer from problems of incomplete resetting (by inheritance, intermittent cover/exposure, transport under unfavourable conditions) and/or a lack of suitable (organic) material. Rock surface luminescence burial dating (RS

QUANTITATIVE COARSE-GRAINING OF MARKOV CHAINS

Coarse-graining techniques play a central role in reducing the complexity of stochastic models and are typically characterized by a mapping which projects the full state of the system onto a smaller set of variables which captures the essential features of the system. Starting with a continuous-time Markov chain, in this work we propose and analyze an effective dynamics, which approximates the dyn

Tailoring the Photophysical Properties of a Homoleptic Iron(II) Tetra N-Heterocyclic Carbene Complex by Attaching an Imidazolium Group to the (CNC) Pincer Ligand─A Comparative Study

We here report the synthesis of the homoleptic iron(II) N-heterocyclic carbene (NHC) complex [Fe(miHpbmi)2](PF6)4 (miHpbmi = 4-((3-methyl-1H-imidazolium-1-yl)pyridine-2,6-diyl)bis(3-methylimidazol-2-ylidene)) and its electrochemical and photophysical properties. The introduction of the π-electron-withdrawing 3-methyl-1H-imidazol-3-ium-1-yl group into the NHC ligand framework resulted in stabilizat

Build Forward Fairer : Covid-19, Lessons Learned

The article discusses the importance of adopting a human rights-based approach in addressing the lessons learned from the Covid-19 pandemic. The article highlights the case of a human rights-based hospital in Sweden that actively reached out to vulnerable individuals in the community during the pandemic, emphasizing how the human rights-based approach contributes to building trust and thereby real