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Impact of fine-needle aspiration cytology in thyroidectomy extent and associated surgical morbidity in thyroid cancer

Purpose: To assess the impact of fine-needle aspiration cytology (FNAC) in the extent of surgery in patients with thyroid cancer (TC) and the associated surgical morbidity in primary and completion setting. Methods: A Swedish nationwide cohort of patients having surgery for TC (n = 2519) from the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal surgery between 2004 and 2013 was o

What we talk about when we talk about electricity : A thematic analysis of recent political debates on Swedish electricity supply

The Swedish electricity system is undergoing a transition unprecedented in both speed and scale, thereby exposing a number of policy-related controversies. In this study, six central themes in the on-going debates around the security of electricity supply in Sweden are identified based on a material of over 1000 news articles, published between the years 2010–2022. By applying the themes to the po

A practical solution for multivariable control of temperature and humidity in greenhouses

This paper presents a simple and effective control solution to regulate temperature and humidity inside a greenhouse, which are the main climatic variables affecting crop growth and health. A multivariable control strategy with inverted decoupling is proposed in two schemes. The nighttime control scheme uses heating and dehumidification, and the daytime control scheme uses natural ventilation, deh

Disk counting statistics near hard edges of random normal matrices : The multi-component regime

We consider a two-dimensional point process whose points are separated into two disjoint components by a hard wall, and study the multivariate moment generating function of the corresponding disk counting statistics. We investigate the “hard edge regime” where all disk boundaries are a distance of order [Formula presented] away from the hard wall, where n is the number of points. We prove that as

Deglaciation patterns in the Upper Zemmgrund, Austria : An exploration of clean-ice disintegration scenarios

The European Alps are rapidly losing glacier mass due to climatic warming and are anticipated to be largely ice-free by the year 2100. Long-term glacier monitoring in the Alps provides a record of anthropogenically-driven climate change since the Little Ice Age maximum in ~1850. Understanding these long-term glacier changes provides a basis for mitigating hazards (e.g., mass movements) associated

Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis

Optic neuritis (ON) is associated with numerous immune-mediated inflammatory diseases, but 50% patients are ultimately diagnosed with multiple sclerosis (MS). Differentiating MS-ON from non-MS-ON acutely is challenging but important; non-MS ON often requires urgent immunosuppression to preserve vision. Using data from the United Kingdom Biobank we showed that combining an MS-genetic risk score (GR

Microbial composition, functionality, and stress resilience or susceptibility : unraveling sex-specific patterns

Background: Following exposure to traumatic stress, women are twice as likely as men to develop mood disorders. Yet, individual responses to such stress vary, with some people developing stress-induced psychopathologies while others exhibit resilience. The factors influencing sex-related disparities in affective disorders as well as variations in resilience remain unclear; however, emerging eviden

Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome

DNA mismatch repair (MMR) is thought to contribute to the onset and progression of Huntington disease (HD) by promoting somatic expansion of the pathogenic CAG nucleotide repeat in the huntingtin gene (HTT). Here we have studied constitutional HTT CAG repeat size in two cohorts of individuals with Lynch syndrome (LS) carrying heterozygous loss-of-function variants in the MMR genes MLH1 (n = 12/60;

Benchmarking performance through efficiency analysis trees : Improvement strategies for colombian higher education institutions

We introduce benchmarking analysis based on state-of-the-art machine learning techniques applied to the measurement of efficiency to assess the performance of Higher Education Institutions (HEIs). We rely on Efficiency Analysis Trees (EAT) and its Convexified frontier counterpart (CEAT) to assess the efficiency of 144 private HEIs in Colombia and compare the results with those achieved with classi

Measures of cognitive ability and choice inconsistency

Cognitive skills affect individual choices. Researchers commonly use Raven's Progressive Matrices (RPM) tests and the Cognitive Reflection Test (CRT) to assess the relationship between cognitive abilities and economic decision making. In this paper, we study the relationship between these measures, and investigate the extent to which they are correlated and whether they are best described as subst

Multidisciplinary monitoring of an in-situ remediation test of chlorinated solvents

Pollutions on and within the underground poses risks for groundwater contamination and is a widespread global problem. Common remediation methods based on digging and removal can be expensive and have limitations, while in-situ remediation is an attractive alternative. However, there is a need to develop tools to monitor the effectiveness both in terms of the successful injection of remediation fl

Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer : A phase I and III open label randomized controlled registry-based clinical trial protocol

Standard treatment for patient with peritoneal metastases from colorectal cancer is cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). In recent years, the efficacy of oxaliplatin-based HIPEC has been challenged. An intensified HIPEC (oxaliplatin+irinotecan) in combination with early postoperative intraperitoneal chemotherapy (EPIC) has shown increased recurrence-fr

The 'Most Ideal' Peter Handke? : Aesthetics and Ethics as Criteria for the Nobel Prize in Literature

The Nobel Prize in Literature to the Austrian writer Peter Handke in 2019 gave new attention to one of the basic, and historically highly disputed (cf. Espmark 2001, 2021), questions in relation to the practice of the world’s most important literary prize – on what grounds, aesthetic or otherwise, does the Swedish Academy award the prize? In the aftermath of the 2019 prize to Handke, there was an

Genetic correlations and causal relationships between cardio-metabolic traits and sepsis

Cardio-metabolic traits have been reported to be associated with the development of sepsis. It is, however, unclear whether these co-morbidities reflect causal associations, shared genetic heritability, or are confounded by environmental factors. We performed three analyses to explore the relationships between cardio-metabolic traits and sepsis. Mendelian randomization (MR) study to evaluate the c

Den mångetniska äldreomsorgen ur hemtjänstanvändares perspektiv

Den som använder äldreomsorg möter ofta personal som är utlandsfödd eller har en annan etnicitet än den svenska. Syftet med den här studien var att undersöka äldre hemtjänstanvändares uppfattningar om ”utländsk” personal. Studien baseras på 34 intervjuer med äldre som använder hemtjänst. Resultaten visade att språkproblem var vanliga, men att den övervägande bilden av personalen var positiv, vilke

Clinical Course, Laboratory Findings, and Prognosis of SARS-CoV-2 Infection in Infants up to 90 Days of Age: A Single-Center Experience and a Proposal for a Management Pathway

Aim: To provide a comprehensive description of the clinical features, biochemical characteristics, and outcomes of infants up to 90 days old with COVID-19. Moreover, to assess the severity of the disease and propose an effective management pathway. Methods: Retrospective single-center study spanning three years. Patient data includes age, sex, symptoms, comorbidities, blood and urine test results,

Automatic procedure for modelling, calibration, and optimization of a three-component chromatographic separation

The current landscape of biopharmaceutical production necessitates an ever-growing set of tools to meet the demands for shorter development times and lower production costs. One path towards meeting these demands is the implementation of digital tools in the development stages. Mathematical modelling of process chromatography, one of the key unit operations in the biopharmaceutical downstream proc

Bordering Principles and Integration in Urban Context

In this paper we reflect on how bordering emerge in urban integration processes in relation to two geopolitical belongings. The paper emanates from a performative dialogic event, labelled Lund Irbid Parallel Walk connecting two geopolitical regions: one in Europe through the city of Lund in the South of Sweden, and one in the Middle East that is Irbid located in the North of Jordan. Here, we refle

Exploring the development of heterogeneous contracting capabilities : the role of organizational design

Previous research on learning to contract and contracting capabilities suggests that firms in interorganizational relationships adopt contractual designs that economize on transaction costs, and over time learn to govern their relationships in a more efficient manner by incrementally aligning contractual terms with transaction attributes based on new experiences made in their relationships. We aug