The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. DnaK and trigger factor (TF) are ubiquitous bacterial molecular chaperones that assist in protein folding, as well as preventing protein misfolding and aggregation. In Escherichia coli, DnaK and TF possess partially overlapping functions. Their combined depletion results i

Efter flera år av snabba lagändringar på asylområdet kommer allt fler alarmerande rapporter om att människor på flykt, inte minst barn och unga, far illa efter att ha sökt asyl i Sverige. Därför bildas nu en granskningskommission för att undersöka vad det är som hänt och hur situationen kan förbättras.

Background: To evaluate the psychosocial consequences of surveillance with whole-body MRI (WB-MRI) in individuals with the heritable TP53-related cancer (hTP53rc) syndrome, also known as the Li-Fraumeni syndrome, with regard to cancer worry, perceived benefits and risks to surveillance and overall health. Patients and methods: Since 2016, the national Swedish TP53 Study (SWEP53) has offered survei

Background: The underlying factors of the male predominance in Autism Spectrum Disorders (ASD) are largely unknown, although a female advantage in social communication has been pointed out as a potential factor. Recently, attention has been given to ASD as a sensory processing disorder, focusing on the audio-visual temporal processing paramount for the development of communication. In ASD, a devia

Description of genetic phenomena and variations requires exact language and concepts. Vast amounts of variation data are produced with next-generation sequencing pipelines. The obtained variations are automatically annotated, e.g., for their functional consequences. These tools and pipelines, along with systematic nomenclature, mainly work well, but there are still some problems in nomenclature, o

Cyperus fuscus was thought to be extinct in Sweden until it was rediscovered at Lake Vombsjön, Skåne, after 63 years in 2013. The species also occurred at the lake 2014—2021, but in very variable numbers. The variation depended largely on the water level during late summer. Favourable conditions in form of low levels in late summer have also occurred prior to 2013, though less frequently than in r

Mangroves provide numerous environmental benefits, such as carbon sequestration, water purification, climate change mitigation, and flood and Tsunami impact reduction. Despite these unique advantages, mangroves are threatened by the combined adverse impacts of human activities and climate change. Therefore, it is essential to implement reasonable practices to avoid further degradation of mangroves

We characterize the common range of the adjoints of cyclic multiplication operators on the Drury-Arveson space. We show that a function belongs to this common range if and only if its Taylor coefficients satisfy a simple decay condition. To achieve this, we introduce the uniform Smirnov class on the ball and determine its dual space. We show that the dual space of the uniform Smirnov class equals