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Background: In atopic asthma, chronic Th2-biased inflammation is associated with an increased risk of pneumococcal infection. The anionic phosphoglycoprotein osteopontin (OPN) is highly expressed in asthma and has been ascribed several roles during inflammation. This study aimed to investigate whether OPN affects inflammation and vulnerability to pneumococcal infection in atopic asthma. Methods: H

Fifth generation cellular systems will be deployed in the microwave and millimeter–wave (mmWave) frequency bands (i.e., between 0.5–100 GHz). Propagation characteristics at these bands have a fundamental impact on each aspect of the cellular architecture, ranging from equipment design to real-time performance in the field. While we have a reasonable understanding of the propagation characteristics

In this paper, we take a fundamental look at the interference characteristics of a lens-based millimeter-wave (mmWave) multiuser multiple-input multiple-output system (MU-MIMO) system. We consider a hybrid architecture, implemented via a bank of radio-frequency (RF) switches which perform beam selection followed by low-complexity uplink maximum-ratio combining (MRC) at baseband. Considering a Rotm

The present invention relates to peptides derived fromapolipoprotein A-I (apoA-I) and their use for treatment or prevention ofdiseases and disorders associated with hyper-glycaemia.

We consider a massive multiple-input multiple- output system with minimum-mean-squared-error processing on the uplink. A novel analytical framework is proposed to approximate the instantaneous signal-to-interference-plus-noise- ratio (SINR) of an arbitrary user terminal, as well as, the system sum spectral efficiency. Unlike previous studies, our methodology considers spatially correlated Ricean f

In this paper new modeling techniques of (S- 1 , S) inventory systems (continuous review base-stock inventory systems) with state dependent demand rates are proposed. Examples of single-location (S- 1 , S) inventory systems where the demand, experienced by the system, varies due to the state of the system are, e.g., inventory models with partial backorders, inventory models with lost sales, invent

The recent explosion in size and complexity of datasets and the increased availability of computational resources has led us to what is sometimes called the big data era. In many big data fields, mathematical optimization has over the last decade emerged as a vital tool in extracting information from the data sets and creating predictors for unseen data. The large dimension of these data sets and

Pyrimethanil (PYM) is a fungicide used pre- and post-harvest on many crops. It has a low acute toxicity but is of toxicological concern because of its antiandrogenic properties. The aim of the current work was to investigate some metabolism and estimate elimination kinetics of PYM in humans after experimental oral and dermal exposure. A liquid chromatography triple quadrupole mass spectrometry (LC

Surgical site infections (SSIs) in dermatologic surge- ry contribute to unwanted healthcare costs and are complications that cause su ering in patients. The aim of this thesis was to explore clinical, diagnos- tic, and pathogenic aspects of SSIs in dermatologic surgery.In study I, we examined bacterial dynamics during normal wound healing and SSIs. We found that quantifying bacteria from wounds wa

Ecological intensification may reduce environmental externalities of agriculture by harnessing biodiversity to benefit regulating ecosystem services. However, to propose management options for the production of such services, there is a need to understand the spatiotemporal dynamics of net effects between ecosystem services and disservices provided by wild organisms across taxonomic groups in rela

Objective: To describe the clinical and ultrasound characteristics of ovarian pure clear cell carcinoma. Methods: This was a retrospective study involving data from 11 ultrasound centers. From the International Ovarian Tumor Analysis (IOTA) database, 105 patients who had undergone preoperative ultrasound examination by an experienced ultrasound examiner between 1999 and 2016 were identified with a

Introduction and aim: Hip and knee replacement surgery is very demanding for patients. Medication consumption is further increased by perioperative anxiety. Besides pain killer and anxiolytic medications, patients' recovery can be enhanced by applying therapeutic suggestions, which are easily applicable during the patient-physician communication. Method: In our prospective, randomized, controlled

Objective: Children of mothers with severe mental illness are at significantly increased risk of developing intellectual disability. Obstetric complications are also implicated in the risk for intellectual disability. Moreover, children of mothers with severe mental illness are more likely to be exposed to obstetric complications. The purpose of this study was to examine the independent and joint

To fend off microbial pathogens and herbivores, plants have evolved a wide range of defense strategies such as physical barriers, or the production of anti-digestive proteins or bioactive specialized metabolites. Accumulation of the latter compounds is often regulated by transcriptional activation of the biosynthesis pathway genes by the phytohormone jasmonate-isoleucine. Here, we used our recentl

Jordbruk utgör den största ekonomiska sektorn och har den högsta sysselsättningsgraden i Tchad. Samtidigt så genomgår den hastiga förändringar på grund av populationsökning, institutionella reformer, konflikter i grannländerna, ökande globaliserade handelsnätverk, samt miljöförändringar. Men trots dess betydelse för lokala uppehällen och ekonomisk tillväxt, så är de specifika förändringsmönstrena Agriculture constitutes the largest economic sector and professional occupation in Chad, and is undergoing rapid changes due to processes of population increase, institutional reforms, conflicts in neighbouring countries, increasingly globalized trade networks, and environmental changes. But despite their importance for livelihoods and economic growth, the specific patterns and drivers of change i