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Non-specific structural chromosomal aberrations (CAs) observed in peripheral blood lymphocytes of healthy individuals can be either chromosome-type aberrations (CSAs) or chromatid-type aberrations (CTAs) depending on the stage of cell division they are induced in and mechanism of formation. It is important to study the genetic basis of chromosomal instability as it is a marker of genotoxic exposur

Alkaliskt sfingomyelinas, en antiinflammatorisk faktor som kan motverka colit och colorektal cancer Rui-Dong Duan, Erik Hertervig, Åke NilssonBakgrund: Borstbrämsenzymet alkaliskt sfingomyelinas (alk-SMas) som vi upptäckt, renat och klonat hydrolyserar sfingomyelin (SM) och den proinflammatoriska glycerofosfolipiden platelet activating factor (PAF). Metaboliter av SM är anticarcinogena och inaktiv

Background: The substitution of bisphenol A (BPA) by bisphenol B (BPB), a very close structural analog, stresses the need to assess its potential endocrine properties.Objective: This analysis aimed to investigate whether BPB has endocrine disruptive properties in humans and in wildlife as defined by the World Health Organization (WHO) definition used in the regulatory field, that is, a) adverse ef

This thesis concerns the theoretical analysis of thermoelectric transport properties and single electron sources in mesoscopic conductors. Wepropose two types of thermoelectric heat engines and analyze them with thehelp of performance quantifiers. We also investigate and compare theproperties of different single electron sources, focusing on their coupledcharge and energy transport. As a common de

Handelsbranschen befinner sig mitt i en tid av stora omfattande förändringar, vad gäller till exempel människors ändrade köpmönster, digitalisering, urbanisering och globalisering . En av de stora konsekvenserna av dessa förändringar är förändringen i relationen mellan handel och plats.Detta har varit utgångspunkten för forskningsprogrammet ”Retail Destination” vars resultat redovisas i denna skri

El Sistema, the originally Venezuelan music teaching movement is spreading worldwide, suggesting Western classical music as a tool for counteracting poverty and segregation. In Sweden, this represents an interesting and perhaps pro- voking twist, as the hegemony of classical music in music teacher education has since long been replaced by the hegemony of popular music. Based on eldwork during the

I kolonin Danska Västindien utnjyttades förslavade kvinnor inte bara som arbetskraft, de uttnyttjades också sexuellt. Möjligheterna till motstånd var så gott som obefinntliga. Ändå kämpade slavkvinnor för rätten till att bestämma över egen kropp.

Early models of radicalisation of belief and the use of violence were described in terms of progressive linear models; staircases (Moghaddam, 2005), pathways (McCauley & Moskalenko, 2008) and conveyor belts (see Pankhurst, 2013). In association with the different proposed models, definitions of radicalisation are often chosen by the researcher, resulting in inconsistencies within theliterature

The present invention provides methods that increases the graft survival rate of pancreatic islets after pancreatic islet transplantation, maintains the survival of pancreatic islets ex vivo, and reduce the number of transplanted pancreatic islets required for normalizing blood glucose levels. When performing pancreatic islet transplantation, by pre-incubating pancreatic islets with stem cells or

Urethral obstruction in cats is an emergency that without adequate intervention may progress to uremia and death of the patient. Prolonged distension of the bladder will result in loss of contractile function and consequently, bladderatonia and this can become permanent. It is concluded that the pre-pubic urethrostomy in feline is effective for correction of urethral stenosis even afte previous pe

Thoracic trauma is a very common injury in small animal practice and most of them in need of emergency surgery.The main objective of the thoracic stabilization is to allow adequately ventilation as soon as possible. The aim of this report was to describe the use of a catheter needle, a low cost material, for costal osteosyntesis in a dog in the hospital routine. A dog with flail chest was admitted

Background: Chronic pain is a common comorbid complaint in traumatized refugees seeking treatment for posttraumatic stress disorder (PTSD) and depression. However, the effect of comorbid pain on treatment remains under investigated. Objective: To investigate whether pre-treatment pain (severity/interference) predicts outcomes in a multimodal treatment targeting PTSD, depression, anxiety, somatic c

Microbial monitoring of drinking water is required to guarantee high quality water and to mitigate health hazards. Flow cytometry (FCM) is a fast and robust method that determines bacterial concentrations in liquids. In this study, FCM was applied to monitor the dynamics of the bacterial communities over one year in a full-scale drinking water distribution system (DWDS), following implementation o

The paper discusses how families affected by Typhoon Haiyan have been involved in housing reconstruction in the Philippines and the potential for the use of medium-rise buildings. Case study methodology was conducted based on data collected three months after Typhoon Haiyan. Reconstruction projects show different degrees of users involvement such as “reparation of previous makeshift shelter,”“shel

There is an urgent need of improving the lives of 100 million slum dwellers until year 2020. The Habitat Agenda has identified self-help housing among other enabling housing strategies. This paper focuses on mapping organizations and different types of organized self-help housing (OSHH) projects since year 2000 with the aim of analyzing important lessons from practice. An international survey was

The present invention describes a method for the treatment of tall oil pitch (TOP), said method comprising heating the TOP and optionally additives including water and steam to a temperature of at least 300°C; maintaining the temperature in the reactor at 300°C or higher for a period of time to enable thermal treatment of the TOP to act on components thereof toproduce fatty acids and/or rosin acid

Populärvetenskaplig sammanfattning Främsta källan till läkemedel i miljön är att vi människor inte bryter ner det vi stoppar i oss och att avloppsreningsverk inte heller helt eliminerar resterna i reningsprocessen. Koncentrationerna i naturen är dock ofta låga men vattenlevande organismer kan ackumulera vissa läkemedel så koncentrationen i deras kroppar blir högre än i omgivningen, så kallad bioacPharmaceuticals are found at low concentrations (ng/L) in aquatic environments but bioaccumulation may result in aquatic organisms reaching internal effect levels (µg/L). Environmental hazard assessments include standardized bioaccumulation tests but contrary to the model substances around which the frameworks are built most pharmaceuticals are designed to mimic endogenic chemicals, ionizable, and