Chromosomal instability is a hallmark of many cancers and it has a potential to predict clinical outcome of a cancer patient. We hypothesized that genes whose expression status differs between chromosomal stable and unstable breast tumors represent target genes for the identification of genetic variants predicting breast cancer (BC) risk, disease progression, and survival. We used a published list

We present a simple, classical density functional approach to the study of simple models of room temperature ionic liquids. Dispersion attractions as well as ion correlation effects and excluded volume packing are taken into account. The oligomeric structure, common to many ionic liquid molecules, is handled by a polymer density functional treatment. The theory is evaluated by comparisons with sim

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab 302: E950-E960, 2012. First published January 31, 2012; doi:10.1152/ajpendo.00466.2011.-Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. Howe

I artikeln presenteras ett projekt om forskares behov av stöd, genomfört 2012, inom biblioteksnätverket Lunds universitets bibliotek (LUB). Projektet består av a) en litteraturöversikt med fokus på definitioner av och exempel på forskarstöd samt vilka behov och erfarenheter forskare själva har av forskarstöd, b) en enkätundersökning av befintlig forskarservice från biblioteken inom (LUB), ett deceThis article presents a 2012 project on researchers’ need of support at Lund University Libraries (LUB). The project was three folded with the object to identify areas where the present research support services ought to be developed and strengthened. The project contains a) a literature review focusing on definitions and examples of research support services as well as researchers’ needs and expe

This is a review of a book on Ephrem the Syrian published in Danish and containing one of the biographies of the Syrian saint translated into Danish.

An exact treatment of the van der Waals interaction between two spherical dielectric bodies possessing purely classical degrees of freedom is presented. The spheres are described by multipole expansions of their fluctuating charge distributions, and the correlation between the fluctuations are taken into account using classical electrostatics and statistical mechanics. The presented approach avoid

The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 and 2007. The document contains chapters on definitions and classification, we now also propose definitions for 'difficult to treat' rhinosinusitis, control of disease and better definitions for rhinosinusitis in children. More emphasis is placed on the diag

Studies of the spin and parity quantum numbers of the Higgs boson are presented, based on protonproton collision data collected by the ATLAS experiment at the LHC. The Standard Model spin-parity J(P) = 0(+) hypothesis is compared with alternative hypotheses using the Higgs boson decays H -> gamma gamma, H -> ZZ* -> 4l and H -> WW* -> l nu l nu, as well as the combination of these channels. The ana

The MAX IV pro-injector will have one thermionic and one photocathode S-band RF gun, where the former will be used for ring injections. During ring injections, the bunches leaving the pre-injector have a structure that consists of ten 10 ns bunch trains, each containing three bunches. A chopper system consisting of two striplines and an adjustable aperture is used, where the desired bunch structur

Bör filmarkiv främst tillvarata eller förevisa sina samlingar? Noggrant bevara och katalogisera eller visa och sprida dem? Henri Langlois, grundaren av Cinémathèque Français menade att om film aldrig visas, utan endast förvaras i metallburkar, kommer den att sluta som skosmörja. Den digitala utvecklingen förefaller givit honom rätt; bred tillgänglighet till filmens historia är allra viktigast på e

The binuclear title complex, [Zn2(C33H33N6O)(CH3COO2)(CH3OH)](ClO4)2, was synthesized by the reaction between 2,6-bis-({[bis-(pyridin-2-yl)meth-yl]amino}-meth-yl)-4-methyl-phenol (H-BPMP), Zn(OAc)2 and NaClO4. The two Zn(II) ions are bridged by the phenolate O atom of the octadentate ligand and the acetate group. An additional methanol ligand is terminally coordinated to one of the Zn(II) ions, re

By the end of 2020, all EU member states need to ensure that all newly constructed buildings consume ` nearly zero' energy and that their energy needs are produced locally as much as possible and with renewable sources; a concept called nearly Zero Energy Buildings (ZEB). At the same time, more and more people live in cities, where the access to local renewable energy sources -wind and solar-is li

The effects of color reconnection (CR) at e(+) e(-) colliders are revisited, with focus on recently developed CR models. The new models are compared with the LEP2 measurements for e(+) e(-) -> W+W- -> q(1)(q) over bar (2)q(3)(q) over bar4 and found to lie within their limits. Prospects for constraints from new high- luminosity e(+) e(-) colliders are discussed. The novel arena of CR in Higgs decay

This paper describes an analysis of the angular distribution of W -> e nu and W -> mu nu decays, using data from pp collisions at root s = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb(-1). Using the decay lepton transverse momentum and the missing transverse momentum, the W decay angular distribution projected onto the transver

Two new solvates were prepared in the system Cu(I) I using a solvolysis reaction. The structures for both of them were solved by X-ray crystallography, showing that they constitute two modifications of the same compound with the net formula [Cu4I6](P(C6H5)(4))(2)center dot 2OC(CH3)(2). Both types of crystals show vivid fluorescence when exposed to UV light. The formation of the first modification

In the large majority of product development projects, computer-based design analyses are performed to assess the feasibility of potential technical solutions. As a first step to bring about a deeper understanding of the interactions between the engineering design and the design analysis activities, a survey has been performed in industry. The results of the survey cover: the use of design analysi

Popular Abstract in Swedish Bränslecellen uppfanns redan 1838, det kommersiella genombrottet dröjde till 2007, den framtida potentialen är mycket lovande Domedagsprofetior angående växthuseffektens betydelse för livet på jorden når oss via media allt oftare. Bränsleceller är mycket lovande för ett framtida miljövänligt samhälle. Hög energieffektivitet och inga utsläpp av koldioxid, kväveoxider elFuel cells are electrochemical devices that directly transform chemical energy into electricity. They are promising for future energy systems, since they are energy efficient, able to use renewable fuels and, when hydrogen is used as fuel, there are no direct emissions of greenhouse gases. Various improvements are made during the recent years, however the technology is still in the early phases of