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The non-random location of human oncogenes and tumour suppressor genes

We have analysed 994 sites for oncogenes and tumour suppressor genes located within human chromosome bands. The data presented disclose that: 1) These cancer genes build ridges as well as hot spots, which are not related to the position of other types of genes present in these chromosomes. 2) The frequency of cancer genes is not directly related to chromosome length, to the number of DNA bases per

Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

Class I and class II MHC-restricted T cells specific for proteins present in myelin have been shown to be involved in autoimmunity in the central nervous system (CNS). It is not yet known whether CD1d-restricted T cells reactive to myelin-derived lipids are present in the CNS and might be targeted to influence the course of autoimmune demyelination. Using specific glycohpid-CD1d tetramers and clon

Jämställdhetsrevolutionen finns i lagstiftningen

This article discusses Swedish gender equality policy and excellent gender equality laws. The problem is not a lack of policy documents and laws, the problem is turning this law system in to practise.

Paniken i filmfabriken

Om den politiska svartlistningen av filmarbetare i den amerikanska filmindustrin under 1940- och 1950-talen.

Svenska språkets framtid

Looking backwards the history of Swedish is characterized by the growing impportance of written language, increased standardization of written and spoken language, growth of the Swedish vocabulary. It is hypothesized that this development will stagnate in the future. The hypothesis ist tested in a discussion against the background of a number of societal phenomena that can be expected to affect th

Genetic and Environmental Influences on Mothering of Adolescents: A Comparison of Two Samples

This study examined 2 samples of adolescents and mothers using a child-based design (Nonshared Environment in Adolescent Development [NEAD] project, N = 395 families) and a parent-based design (Twin Moms [TM] project, N = 236 twin family pairs) to compare genetic and environmental influences on mothering. For both samples, the same measures of positivity, negativity, control, and monitoring were u

Book and Library History

A short sketch of the concept of Book and Library History as a field of study, according to the author, holder of the Chair in that subject at Lund University.

Mixed infection with two types of hepatitis C virus is probably a rare event

A search for the simultaneous presence of two hepatitis C virus (HCV) types in sera of a group of chronically infected intravenous drug users, hemodialysis patients and hemophiliacs from Sweden and Russia was performed with two genotyping methods based on the use of type-specific primers from core and NS4 regions of the viral genome. An important feature of NS4 based assay is that type-specific pr

Sympathetic and parasympathetic neuropathy are frequent in both type 1 and type 2 diabetic patients.

OBJECTIVE—The aim of this study was to evaluate the frequency of sympathetic versus parasympathetic neuropathy among type 1 and type 2 diabetic patients. RESEARCH DESIGN AND METHODS—There were 43 patients with type 1 and 17 with type 2 diabetes who were investigated. Sympathetic nerve function was assessed by measurement of the vasoconstriction (VAC) index by laser Doppler perfusion imaging of a