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Monica Z:s säregna resa

Review of Klas Gustafson's biography of Swedish singer Monica Zetterlund, "Enkel, vacker, öm".

Associations of Subjective Sleep Quality with Wearable Device-Derived Resting Heart Rate During REM Sleep and Non-REM Sleep in a Cohort of Japanese Office Workers

Background: Associations between subjective sleep quality and stage-specific heart rate (HR) may have important clinical relevance when aiming to optimize sleep and overall health. The majority of previously studies have been performed during short periods under laboratory-based conditions. The aim of this study was to investigate the associations of subjective sleep quality with heart rate during

A judge must not be influenced by fear. Must a judge be brave? : The duty of judges to defend judicial independence and the rule of law

It is not acceptable that a judge because of ‘fear’ hands down a wrongful judgment. This was mentioned already by Isidore of Seville in his Sententiae and is part of the oaths of judges in many jurisdictions, from the 1230s onwards until this day. The ‘fear’ that is relevant could relate to one of the parties but also other persons in power. Thus, it relates not only to impartiality but – above alIt is not acceptable that a judge because of ‘fear’ hands down a wrongful judgment. This was mentioned already by Isidore of Seville in his Sententiae and is part of the oaths of judges in many jurisdictions, from the 1230s onwards until this day. The ‘fear’ that is relevant could relate to one of the parties but also other persons in power. Thus, it relates not only to impartiality but – above al

Fast Parallelizable Misuse-Resistant Authenticated Encryption : Low Latency (Decryption-Fast) SIV

In this paper, we present two new provable nonce-misuseresistantAEAD modes based on tweakable block ciphers and universalhash functions. These new modes target equipping high-speed applicationswith nonce-misuse-resistant AEAD (MRAE). The first mode, LowLatency Synthetic IV (LLSIV), targets similar performance on single-coreplatforms to SCT-2, while eliminating the bottlenecks that make SCT-2not fu

Continued cancer drug approvals in Japan and Europe after market withdrawal in the United States : A comparative study of accelerated approvals

Regulatory authorities must balance ensuring evidence of efficacy and safety of new drugs. Various regulatory pathways, such as the accelerated approval program in the United States (US), allow authorities to quickly approve drugs for severely ill patients by granting market authorization based on surrogate end points and pending confirmatory trials. In this cross-sectional study, we considered 23

No title

The relationship between bibliography and book history is discussed in three cases based on the the national bibliography of Denmark: The system of book formats as a system of communication. The bibliographical development of chap books in the eighteenth and nineteenth century, and the bibliographical change in the author function in the eighteenth century.

Förebygga självskadebeteende och suicidförsök hos barn och ungdomar – effekter av riktade interventioner. : En systematisk översikt och utvärdering av medicinska, hälsoekonomiska och etiska aspekter

HuvudbudskapDialektisk beteendeterapi för ungdomar (DBT-A) förebygger återfall i självskadebeteende. Internetförmedlad känsloregleringsterapi (IERITA) kan förebygga nya episoder av icke-suicidalt självskadebeteende.SlutsatserEfter att ha granskat den vetenskapliga litteraturen har SBU dragit följande slutsatser:DBT-A minskar antalet ungdomar med självskadebeteende som får ett återfall. Behandlinge

Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit

Protein-ligand complex formation is fundamental to biological function. A central question is whether proteins spontaneously adopt binding-competent conformations to which ligands bind conformational selection (CS) or whether ligands induce the binding-competent conformation induced fit (IF). Here, we resolve the CS and IF binding pathways by characterizing protein conformational dynamics over a w

Sweden’s excess mortality in 2020–2022 and reporting in the media

Aim: The aim was to scrutinize the report in March 2023 that Sweden’s excess mortality was lowest in 2020–2022 compared with other European Union and Nordic countries, a report that received great national and international attention. Study design: Comparison of excess mortality in Sweden and Norway. Methods: Excess mortality for 2020–2022 was calculated for Sweden and Norway, the country with per

Influence of marker-selection method in radiostereometric analysis of total knee arthroplasty on tibial baseplate migration patterns : a secondary analysis of a randomized controlled trial with 5-year follow-up

Background and purpose — Different marker-selection methods are applied to represent implant and tibial seg-ments in radiostereometric analysis (RSA) studies of total knee arthroplasty (TKA). Either a consistent set of markers throughout subsequent RSA examinations (“consistent-marker method”) is used or all available markers at each follow-up (“all-marker method”). The aim of this secondary analy