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Background & AimsYAP (Yap1) and TAZ (Wwtr1) are transcriptional co-activators and downstream effectors of the Hippo pathway, which play crucial roles in organ size control and cancer pathogenesis. Genetic deletion of YAP/TAZ has shown their critical importance for embryonic development of the heart, vasculature, and gastrointestinal mesenchyme. The aim of this study was to determine the functi

A low-profile wideband tri-polarized MIMO antenna is proposed in this paper. Based on characteristic mode analysis of a circular patch, four slots are etched symmetrically on the patch to transform the high-order monopole-like modes into broadside modes with lower resonant frequencies. Four sets of shorting pins are also applied to simultaneously adjust the resonant frequencies of the monopole-lik

This paper engages with the micro action of lifestyle enterprising from an interactionist perspective. The here-and-now action of enterprising is examined in the using the microsociology of Erving Goffman in a single observational case study of tourism lifestyle enterprising in Sweden. The findings illustrate the blurring of assorted personal and commercial domains in the performance of enterprisi

Abstract: The aim of this chapter was to analyze associations between measures of cortisol in salivaand mental health and to see if divergent results were functions of the methods used. Measures ofmental health outcome included Major Depressive Disorder (MDD), symptoms of depression, andsymptoms of anxiety, Burnout (BO), and Vital Exhaustion (VE). Only studies on otherwise healthyindividuals were

The aim of this chapter was to analyze associations between measures of cortisol in saliva withmeasures of perceived stress, using the Perceived Stress Scale (PSS), and of psychological resources interms of mastery, locus of control, self-esteem and sense of coherence. Only studies on healthy individualswere included and cortisol measures were grouped into single time point measures, deviation mea

The aim of this paper is to explore the relationship between individual leaders’ career trajectories and organizational structure and identity in Italian civil society organizations (CSOs) active at national level. The analysis in this qualitative study draws on two sets of data, semi-structured interviews with leaders on their career trajectories and their understanding of what it takes to become

Substitution of IgG in antibody deficiency or application of high-dose intravenous IgG (IVIg) in patients with autoimmunity are well-established treatments. Data on the mode of action of IVIg are, however, controversial and may differ for distinct diseases. In this study, we investigated the impact and molecular mechanism of high-dose IgG treatment in murine autoantibody-induced skin inflammation,

Companies and corporate foundations have become important players in philanthropy. For many companies, philanthropy is part of their corporate social responsibility (CSR) policy. They brought their entrepreneurial customs, values and expectations into the world of philanthropy. This gave rise to new forms of philanthropy next to the conventional form of donations. These developments lead to severa

Software evolves continuously. As software evolves, it's code bases require implementations of new features. These new functionalities are sometimes mere extensions of existing functionalities with minor changes. A commonly used method of extending an existing feature into a similar new feature is to copy the existing feature and modify it. This method of extending feature is called "Copy-paste-mo

Today's dynamic invariant detectors often produce invariants that are inconsistent with program semantics or programmer knowledge. We improve the consistency of dynamically discovered invariants by considering second-order constraints. These constraints encode knowledge about invariants, even when the invariants themselves are unknown. For instance, even though the invariants describing the behavi

How can we, as IR scholars, contribute to the daunting task of crafting a different world? In this paper, I suggest that we begin by looking towards art. Based on a reading of Jacob Remin’s art project ‘Harvesting the Rare Earth,’ I consider how the material imaginary presented in this particular work of art – bio-engineered worms that can extract rare earth minerals from e-waste – provides IR sch

While the question of how images matters in world politics is a pertinent issue in contemporary International Relations (IR) theory, little attention has been paid to the digital interfaces on and through which images are disseminated. This article engages with recent literature on ‘new materialism,’ ‘postphenomenology’ and ‘interface theory’ as one way to bring to the fore the technological mater