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BACKGROUND AND PURPOSE: Pain as a long-term outcome following rectal cancer treatment has received limited attention in previous studies. This prospective cohort study examined pain prevalence up to 5 years post-surgery in patients treated with curative intent. Secondary aims included evaluating pain intensity and its interference with daily life, and comparing pain experiences with a reference po

The HLD-NAC (Hydrophilic-Lipophilic Difference - Net Average Curvature) equation of state is a powerful semi-empirical framework used to predict the phase behavior, solubilization, and interfacial properties of surfactant-oil-water (SOW) systems it is based on the assumption of a normalized curvature for an idealized microemulsion, represented as the coexistence of two fictitious phases: water dro

This essay argues that the concept of global responsibility, as articulated in the works of Karl Jaspers and Hans Jonas, was anticipated in Günther Anders' 1956 opus, Die Antiquiertheit des Menschen. By tracing the phases of Anders' negative anthropology—from his pathology of freedom to the Promethean differential andhis critique of what he considers to be an annihilistic Western stance—I examine

Review of the documentary film "Psychedelic Psalm"

While tau pathology is closely associated with neurodegeneration in Alzheimer's disease (AD), our prior work using multi-modality imaging revealed that mismatch between tau (T) and neurodegeneration (N) may reflect contributions from non-AD processes. The medial temporal lobe (MTL), an early site of AD pathology, is also a common target of co-pathologies such as limbic-predominant age-related TDP-

Abstract – Background: Cytological examination of a fine-needle aspirate (FNA) is a minimally invasive modality that is increasingly used in the diagnosis of lymphoma. Flow cytometry and other ancillary tests make an important contribution to the diagnostic value of FNAs of lymphoid lesions. This review follows the recent publication of the first edition of the WHO Reporting System for Lymph Node,

This pioneering volume explores complex local, global and digital contexts from the perspectives of Digital Theology.The use of and access to digital technology is highly contextual. It differs between regions, generations, classes, religious denominations, and gender. Which problems theologians claim to be important and which developments they ignore is contingent on their cultural, social, econo

This chapter gives an overview of the discussions on online preaching. It identifies and provides examples of three common approaches—message-oriented, media-oriented, and ontology-oriented. In addition, it points to a fourth approach that might be fruitful: the practice-oriented. The chapter also suggests four critical areas in which digital homiletics could benefit from being further developed:

Studies showing that large-scale public health interventions in early life have lastingconsequences are still scarce and rarely disclose the mechanisms. In 1931–1946, the Swedishstate reformed the childbirth institutional system that led to the openings of the new maternitywards and to the gradual decline in home deliveries assisted by midwives. Maternity wardsoffered improved conditions for a mot

Urban meteorology, the study of atmospheric phenomena in urban areas, is vital for understanding the dynamic interactions between rapid urbanization and environmental changes. Over the past two decades (2004–2024), urban heat islands (UHIs), extreme rainfall, pollution, and temperature anomalies have intensified, adversely affecting human health, infrastructure, and ecosystems worldwide. The prese

Breastfeeding confers a wide range of benefits to mothers and children, and in many contextsmay continue for several years after the birth of a child. As a result, breastfeeding duringpregnancy (BDP) is a common occurrence throughout low- and middle-income countries.Nevertheless, yet there has been little research into its association with the health of breastfedchildren or the outcomes of the pre

The high prevalence (>5%) of autoimmune hypothyroidism (AIHT) provides a unique opportunity to dissect genetic contributions to systemic and organ-specific autoimmunity. Here we performed a genome-wide association meta-analysis of 81,718 AIHT cases in FinnGen and the UK Biobank, identifying 418 independent signals (P < 5 × 10−8). At 48 of these loci, a protein-coding variant is, or is highly corre

BACKGROUND: Familial aggregation of stroke is well-documented, yet few studies have examined associations between stroke subtypes-particularly early-onset cryptogenic ischaemic stroke (eCIS)-and broader family history (FH) of cardiovascular disease. Such associations may provide insights into underlying etiologic mechanisms. METHODS: In this multicentre case-control study, we included eCIS patient