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Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries.

INTRODUCTION: Calcitonin gene-related peptide (CGRP) is a neuronal messenger in intracranial sensory nerves and is considered to play a significant role in migraine pathophysiology. MATERIALS AND METHODS: We investigated the effect of the CGRP receptor antagonist, telcagepant, on CGRP-induced cranial vasodilatation in human isolated cerebral and middle meningeal arteries. We also studied the expre

The role of calcium in neutrophil granule-phagosome fusion.

During phagocytosis, neutrophils kill microorganisms by delivering antimicrobial substances to the phagosome. For this, the intracellular targeting and fusion of granules must be strictly regulated and a dependence on the cytosolic concentration of free calcium has been suggested. New evidence show that different mechanisms regulate early and late stages of Fc receptor-mediated phagocytosis. The e

Studier rörande ordförrådsutvecklingen hos barn i skolåldern

Likelihood of acute coronary syndrome in emergency department chest pain patients varies with time of presentation

Background: There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest pain patients varies with the time of presentation. Methods: All patients presenting to the Lund ED at Skåne University Hospital with chest pain or discomfort during 2006 and 20

Trade, Trust, and Networks. Commercial Culture in Late Medieval Italy

Robust Multichannel Detection of Mixtures Using Nuclear Quadrupole Resonance'

Nuclear quadrupole resonance (NQR) is a radio-frequency (RF) spectroscopic technique, able to detect the presence of many high explosives and narcotics. In practice, the weak NQR signal is often corrupted by strong RF interference (RFI); therefore, various multichannel detection algorithms have recently been proposed for NQR. However, these algorithms allow for only a single compound/polymorph, wh

Biomarkers of early chronic obstructive pulmonary disease (COPD) in smokers and former smokers. Protocol of a longitudinal study.

Chronic obstructive pulmonary disease (COPD) is an irreversible disease, diagnosed predominantly in smokers. COPD is currently the third leading cause of death worldwide. Far more than 15 % of smokers get COPD: in fact, most develop some amount of pulmonary impairment. Smoking-related COPD is associated with both acute exacerbations and is closely correlated to comorbidities, such as cardiovascula

Obituary for Prof. Torsten Almén.

Remburs som betalning

Collective Omissions and Responsibility

Brittisk film – styrka och svaghet

Fundamental Limitations on Projective Invariants of Planar Curves

EU Foreign Policy as Others See It – Images of the EU as an International Negotiator

Bergmans filmer i rampljuset

Sextiofyra och åtta istället för tio. Karl XII, Swedenborg och konsten att räkna

Corticosteroides

The impact of seasonal unit roots and vector ARMA modeling on forecasting monthly tourism flows

Optimering av ventilationsluftflödet i kontorsbyggnader - livscykelkostnad för inneklimatsystem

Individualiserade Serviceprogram: En arbetsmodell för familjecentrerad habilitering

Recension av Adrian Heath, Ditte Heath & Aage Lund Jensen 300 Years of Industrial Design: Function, Form, Technique 1700–2000 (New York: Watson–Guptill Publications 2000.