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Deep Decarbonization and Energy Security for Low-Carbon Societies
Lee, Charlottesville och statystriderna i södern : försoning, fortsatt förslavande eller främlingsfientlighet?
Artikel om statystriderna i de amerikanska sydstaterna med särskilt fokus på den omstridda statyn över Robert E. Lee i Charlottesville.
Role of the DNA damage response in human papillomavirus RNA splicing and polyadenylation
Human papillomaviruses (HPVs) have evolved to use the DNA repair machinery to replicate its DNA genome in differentiated cells. HPV activates the DNA damage response (DDR) in infected cells. Cellular DDR factors are recruited to the HPV DNA genome and position the cellular DNA polymerase on the HPV DNA and progeny genomes are synthesized. Following HPV DNA replication, HPV late gene expression is
Extended high-frequency pure tone hearing thresholds and core executive functions
Objective: To examine the relationship between extended high-frequency pure tone hearing thresholds (frequencies 10 to 14 kHz) and working memory capacity (WMC), inhibitory control, and cognitive flexibility. Design: Experimental study measuring correlations between different high-frequency hearing threshold measures and cognitive measures. Study: Pure tone audiometry was assessed in the extended
Rapid syntactic pre-activation in Broca’s area : Concurrent electrophysiological and haemodynamic recordings
Listeners are constantly trying to predict what the speaker will say next. We concurrently measured the electrophysiological and haemodynamic correlates of syntactic pre-activation, investigating when and where the brain processes speech melody cues to upcoming word order structure. Pre-activation of syntactic structure was reflected in a left-lateralised pre-activation negativity (PrAN), which wasListeners are constantly trying to predict what the speaker will say next. We concurrently measured the electrophysiological and haemodynamic correlates of syntactic pre-activation, investigating when and where the brain processes speech melody cues to upcoming word order structure. Pre-activation of syntactic structure was reflected in a left-lateralised pre-activation negativity (PrAN), which wa
Unrelated knowledge combinations : The unexplored potential for regional industrial path development
The article engages in a critical discussion of the related variety/regional branching argument and foregrounds a more differentiated perspective on regional industrial path development. It contributes by (i) sharpening the definition of key concepts, namely specialisation and diversity, related and unrelated variety; (ii) discussing their relevance in local and nonlocal spaces; (iii) scrutinizing
Coffee is associated with lower breast tumor insulin-like growth factor receptor 1 levels in normal-weight patients and improved prognosis following tamoxifen or radiotherapy treatment
Coffee is associated with decreased breast cancer risk, but the impact of body mass index (BMI) in combination with coffee consumption on prognosis is unclear. The suppressive effect of coffee constituents on the insulin-like growth factor receptor 1 (IGF1R) levels in breast cancer cells may play a role. The aim was to investigate the prognostic impact of coffee consumption and possible associatio
Noise in the Tropical Underground
Interest in experimental music scenes from a global perspective has grown in recent years as familiar avant-garde art forms are found ensconced in various communities in many parts of the world. Often, the aesthetic expression found in these scenes could be understood as a mixture of a globally recognized phenomena, such as noise art, and distinctive practices drawn from the situated local culture
Geophysical pre-investigation for a Stockholm tunnel project : Joint inversion and interpretation of geoelectric and seismic refraction data in an urban environment
Underground constructions for public traffic purposes are becoming increasingly important for urban areas in order to use the limited space more efficiently. Several electric resistivity tomography and seismic refraction tomography measurements were performed crossing a water passage near Stockholm during the pre-investigation phase of a tunnel building project. The objective was to determine the
Building the evidence base for current systemic treatments for severe, chronic atopic dermatitis : methotrexate vs. azathioprine
The ELI-ALPS facility : The next generation of attosecond sources
This review presents the technological infrastructure that will be available at the Extreme Light Infrastructure Attosecond Light Pulse Source (ELI-ALPS) international facility. ELI-ALPS will offer to the international scientific community ultrashort pulses in the femtosecond and attosecond domain for time-resolved investigations with unprecedented levels of high quality characteristics. The laser
Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles
The ability to observe ultrafast structural changes in nanoscopic samples is essential for understanding non-equilibrium phenomena such as chemical reactions, matter under extreme conditions, ultrafast phase transitions and intense light-matter interactions. Established imaging techniques are limited either in time or spatial resolution and typically require samples to be deposited on a substrate,
Underwater ERT surveying in water with resistivity layering with example of application to site investigation for a rock tunnel in central Stockholm
We present an approach to underwater electrical resistivity tomography surveying under conditions with several water layers with different resistivity in the water above the electrode layout. The approach is verified against a synthetic model example and tested in full scale on data from a field survey. The field survey was carried out in central Stockholm as part of pre-investigations for a new m
When beggars are choosers—How nesting of a solitary bee is affected by temporal dynamics of pollen plants in the landscape
Wild bees are declining in intensively farmed regions worldwide, threatening pollination services to flowering crops and wild plants. To halt bee declines, it is essential that conservation actions are based on a mechanistic understanding of how bee species utilize landscapes. We aimed at teasing apart how foraging resources in the landscape through the nesting season affected nesting and reproduc
Molecular Movies from Molecular Frame Photoelectron Angular Distribution (MF-PAD) Measurements
We discuss recent and on-going experiments, where molecular frame photoelectron angular distributions (MFPADs) of high kinetic energy photoelectrons are measured in order to determine the time evolution of molecular structures in the course of a photochemical event. These experiments include, on the one hand, measurements where single XUV/X-ray photons, obtained from a free electron laser (FEL) or
Macro-atom versus many-electron effects in ultrafast ionization of C 60
Ionization mechanisms of C60 molecules irradiated by a short intense 800-nm laser pulse are studied. Angle-resolved photoelectron spectra show above-threshold ionization (ATI) patterns with a low peak contrast and a remarkably smooth angular distribution. The results are interpreted by combining two theoretical models. A time-dependent Schrödinger equation (TDSE) calculation based on the B-spline
Integrated approaches to natural resources management—Theory and practice
To meet multiple environmental objectives, integrated programming is becoming increasingly important for the Global Environmental Facility, the financial mechanism of the Multilateral Environmental Agreements, including the UN Convention to Combat Desertification. However, integration is often not well defined. We therefore focus on identifying key aspects of integration and assessing their implem
Which Target Blood Pressure in Year 2018? Evidence from Recent Clinical Trials
The Systolic Blood Pressure Intervention Trial (SPRINT) suggested a favourable effect of lowering blood pressure to < 120/80 mmHg in high-risk hypertensive patients; however, new American guidelines in 2017 have not followed SPRINT but lowered its recommended treatment target to < 130/80 mmHg. We aimed to review the latest research from large randomised controlled trials and observat
New algorithm for simulation of proteoglycan loss and collagen degeneration in the knee joint : Data from the osteoarthritis initiative
Osteoarthritis is a harmful joint disease but prediction of disease progression is problematic. Currently, there is only one modeling framework which can be applied to predict the progression of knee osteoarthritis but it only considers degenerative changes in the collagen fibril network. Here, we have developed the framework further by considering all of the major tissue changes (proteoglycan con