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Chemokine receptor CX3CR1(+) dendritic cells (DCs) have been suggested to sample intestinal antigens by extending transepithelial dendrites into the gut lumen. Other studies identified CD103(+) DCs in the mucosa, which, through their ability to synthesize retinoic acid (RA), appear to be capable of generating typical signatures of intestinal adaptive immune responses. We report that CD103 and CX3C
Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (
Popular Abstract in Swedish Dieselmotorn lanserades för mer än ett sekel sedan och är nu den mest använda motorn inom Europas transportsektor. Detta beror framför allt på dess låga bränsleförbrukning och höga effekt. Avgasutsläppen är dieselmotorns största nackdel eftersom dessa biprodukter från förbränningen har negativa effekter både på folkhälsan och miljön. Därför regleras utsläppen genom lagsDiesel engines are widely used as powertrain solutions for transportation vehicles. Their low fuel consumption and high performance make them attractive, however, their associated pollutant emissions is a major drawback which represent a hazard for public health and the environment. Therefore, the concentrations of the major pollutant species are regulated. Soot, which to a large extent consists
The Global Land-Atmosphere Climate Experiment-Coupled Model Intercomparison Project phase 5 (GLACE-CMIP5) is a multimodel experiment investigating the impact of soil moisture-climate feedbacks in CMIP5 projections. We present here first GLACE-CMIP5 results based on five Earth System Models, focusing on impacts of projected changes in regional soil moisture dryness (mostly increases) on late 21st c
Rapporten beskriver och utvärderar en förändringsprocess till teambaserat arbetssätt på inom primärvården i Sölvesborg, Landstinget Blekinge. Primärvården i Sölvesborg genomgick en omorganisering under 2008 där man gick från "stuprörs organisering" i professionsbaserade avdelningar till två tvärprofessionella avdelningar som i sin tur är indelade i tvärprofessionella team. Omorganiseringen genomfö
The best predictor of good outcome after cardiac arrest is awakening from coma. The longer it takes to regain consciousness, the greater the risk of permanent brain injury. A reliable neurological assessment could previously be performed on day 3 after arrest; absence of or a stereotypic motor reaction to pain and absence of cranial nerve reflexes were reliable predictors of poor outcome, but this
We investigated the mechanical properties, thermal behavior, physical state, and colloidal structure of a model gel network formulated with various ratios of sodium dodecyl sulfate polyacrylamide (SDS) and cetyl/stearyl fatty alcohol (FA) mixture in constant amounts of water (89%). The metastable gel, formed by slowly cooling stirred samples from temperatures above the chain melting temperature (T
Background: Toluene diisocyanate (TDI) is a highly reactive compound used in the production of, e. g., polyurethane foams and paints. TDI is known to cause respiratory symptoms and diseases. Because TDI causes symptoms in only a fraction of exposed workers, genetic factors may play a key role in disease susceptibility. Methods: Workers (N = 132) exposed to TDI and a non-exposed group ( N = 114) we
To trace the concept of evil among one of Canada’s First Nations, the Mi’kmaq, becomes a journey in time and space with a variety of resources and voices to listen to. The concept is biased by the cultural context it is embedded in and by who is to define and who to be defined. The colonizers’ historical demonization of Mi’kmaq cosmology as being worship of the Devil can be reversed into the demon
The present Comite´ Europe´en de Normalisation (CEN) and International Organization for Standardization (ISO) standards for safety, protective and occupational footwear EN ISO 20344–20347 classify footwear as cold protective by a pass/fail test where the limits are set for an allowed 10 °C temperature drop inside the footwear during 30 min at a temperature gradient of ~40 °C. It is questionable if
The aim of this paper is to develop and illustrate an analytic approach that brings the active making and makings of green consumer images to the fore. Efforts to “know” the green consumers have generated multiple representations. Enactments of the green consumer are not innocent but also play a role in shaping how we understand and approach sustainable consumption. Because of this it is important
Abnormal vascularization of solid tumours results in the development of microenvironments deprived of oxygen and nutrients that harbour slowly growing and metabolically stressed cells. Such cells display enhanced resistance to standard chemotherapeutic agents and repopulate tumours after therapy. Here we identify the small molecule VLX600 as a drug that is preferentially active against quiescent c
In 2004 at the ATLAS (A Toroidal LHC ApparatuS) combined test beam, one slice of the ATLAS barrel detector (including an Inner Detector set-up and the Liquid Argon calorimeter) was exposed to particles from the H8 SPS beam line at CERN. It was the first occasion to test the combined electron performance of ATLAS. This paper presents results obtained for the momentum measurement p with the Inner De
Phytochemical investigation of the aerial parts of Potentilla astracanica Jacq. led to the isolation of two isoflavonoid glucosides (1, 2) five flavonoid glycosides (3-7) including one flavone-C-glycoside (7) as well as two flavans (8, 9). The occurrence of isoflavonoids and C-glycosyl flavone is being reported for the first time from the genus Potentilla. (C) 2011 Elsevier Ltd. All rights reserve
This paper proposes a technique for undertaking poverty analyses at city level, by studying the implementation of Costa Rica's social housing policy in the medium-sized city of Liberia. The technique was appraised in relation to its capacity to explore the links between social housing, poverty and inequality, the effects of the implementation of the selected policy and the differences between targ
Given the surprise electoral victory in May 2013 of Iranian President Hassan Rouhani, which was attained on a recurrent platform of reform and change, this article seeks to investigate Iran's reform discourse by looking at how it systematically developed under President Mohammad Khatami (1997–2005). Its chief purpose is to delineate the discourse in a retrospective analytical attempt to show why i
Climate change is occurring more rapidly in the Arctic than elsewhere, and is predicted to have a large impact on biodiversity, since entire cold-adapted ecosystems are likely to disappear. Here, we highlight changes in the insect species richness and community composition of wild bees, butterflies and moths over 60 years in an area situated above the tree limit (Padjelanta National Park) in north
