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Autoimmune diseases are diseases where the immune system attacks the body itself. They are commonly complex diseases with no clear aetiology, a fact that complicates treatment and the study of these diseases. This thesis focuses on the rare group of autoimmune diseases ANCA associated vasculitides (AAV) that are characterized by the presence of anti-neutrophil cytoplasmic antibodies (ANCA) direct

Fires outside school buildings caused by arson are a major problem in Sweden. The initial fire source can involve rubbish or other types of combustibles that can be found at or sometimes brought to the school. As the external fire develops the flames will extend along the façade. If the building is a one-story building, which is a common construction in Swedish school buildings, the fire can sprea

Gamma rays de-exciting isomeric states in the neutron-rich nucleus Os-198(76)122 have been observed following relativistic projectile fragmentation of a 1 GeV per nucleon Pb-208 beam. The ground-state band has properties compatible with oblate deformation. The evolution of the structure of Os isotopes characterized by sudden prolate-oblate shape change is discussed and contrasted with the smooth c

Chip area parameters, such as undeformed chip thickness, equivalent chip thickness, contact edge length, etc., along with tool angles are among defining for the mechanical and thermal conditions of the cutting process. This paper considers the case of external turning with a round insert under variation, in wide range, of back and side rake angles and their influence on the main chip area and surf

The welfare and migration regime of Sweden are undergoing substantial changes, as neo-liberal restructuring is rapidly increasing inequalities, and multicultural policies are in retreat as neo-assimilationist policies are growing. In 2014, the Sweden Democrats, a party conceptualised as culturally racist, was re-elected with 13% of the votes, with a presence in almost all municipalities. While sch

Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung

Detta är den femte rapporten från BirdLife SverigesTaxonomikommitté (Tk). Den innehåller en rad förändringarav Holarktislistan. Listan i sin helhet finns att ladda nedfrån Tk:s webbsida på www.sofnet.org/Tk

Currently available methodologies arguably lack the exquisite control required for producing metal-organic framework (MOF) thin films of sufficient quality for electronic applications. By directing MOF transfer with self-assembled monolayers (SAMs), we achieve very smooth, homogeneous, highly oriented, ultrathin films across millimeter-scale areas that display moderate conductivity likely due to e

Objective To examine disease activity versus treatment as lymphoma risk factors in systemic lupus erythematosus (SLE). Methods We performed case-cohort analyses within a multisite SLE cohort. Cancers were ascertained by regional registry linkages. Adjusted HRs for lymphoma were generated in regression models, for time-dependent exposures to immunomodulators (cyclophosphamide, azathioprine, methotr

Mamma sluta kommentera på min Instagram – du förstör min image Denna kvalitativa studie ämnar öka förståelsen för individers identitetsskapande på sociala medier. En individs identitet förhandlas fram och konstrueras i samspel med andra människor. I och med sociala mediers framväxt utvecklas ständigt nya plattformar där individer kan kommunicera med andra och uttrycka sin identitet. Tidigare forsMom stop commenting on my Instagram – you are ruining my image This qualitative study aims to increase the understanding of how individuals construct their identity through social media. An identity is constructed in interaction with other people. With the development of social media new platforms constantly emerge where individuals can communicate with others and express their identities. Previo

Studiens syfte är att bidra till en djupare förståelse för bakomliggande faktorer till underprissättning på Nasdaq Stockholm, genom att testa ett antal företagsspecifika variablers samband med underprissättning. Studien har en deduktiv ansats och är av kvantitativ karaktär. De variabler som testas i studien är deducerade utifrån tidigare forskning som till övervägande del är genomförd på amerikans

This report deals with lime modification of clay till. Lime modification means that the compaction properties of the soil are improved by the addition of lime. The report consists of three main parts: 1) Description of the geotechnical properties of clay till and how lime modification affects the properties; 2) Description of the implementation of lime modification and the tests conducted at a con

Denna studie undersöker problematiken med den begränsade kunskap om vad kommunikatörer gör när de arbetar strategiskt med kommunikation. Problematiken innebär att strategisk kommunikation har karaktären av en ”svarta lådan”- teori. Genom en kvalitativ fallstudie av två fallorganisationer inom offentlig sektor har jag genom att göra kvalitativa intervjuer studerat vad kommunikatörer gör när de arbe

In recent years, the welfare state has found itself unable to combat issues such as unemployment and poverty, forcing an ever-increasing share of the population to face an increasingly precarious existence. In light of this situation, a growing number of activists and academics have begun to embrace a new means for combating such issues, basic income. Basic income represents a radical departure fr

Purpose: To identify strategies that can be applied to achieve a sustainable position when the equilibrium state has changed. Problem: Research question 1: What factors should be analyzed to predict how disruptive innovations change market structures? Research question 2: What strategies can an innovator apply to achieve a sustainable position at a new equilibrium? Research question 3: How are the

The encoding-retrieval match has been established as a means to improve memory performance. It has recently been proposed that memory performance is not only explained by the encoding-retrieval match and that the cue overload effect needs to be taken into account when predicting memory performance. In the present study, participants were tested using a cued recall methodology. During a study phase