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Extreme hemodilution: Effects of inhalation anesthetics, hypoxia, and blood loss. An Experimental study in pigs.

Popular Abstract in Swedish Effekter av narkosgas, låg syrgashalt och blodförlust under blodspädning (hemodilution) på sövda grisar. Blodspädning (hemodilution) används under operation för att minska behovet av blodtransfusion med dess inneboende risker. Hemodilution innebär att blod tappas före operationsstart och ersätts med en blodkroppsfri lösning. Om en blödning uppstår under operationen blirHemodilution reduces the need for blood transfusion and hereby the risk for transmission of infectious agents. The present study investigated effects on systemic and myocardial circulation and oxygenation, and blood lactate concentrations; induced by nitrous oxide, isoflurane, hypoxia, and uncompensated blood loss, in pigs hemodiluted to a hematocrit of 11%. In addition, indicators of hypovolemia

Pereptgenetic identification of defense

The chapter presents the Defence Mechanism Test (DMT), the Meta-Contrast Technique (MCT) and new innovations within the same family of percept-genetic methods.

Modelling of molybdopterin-dependent enzymes

Popular Abstract in Swedish Molybden ingår som en viktig del i två typer av biologiska system - dels i nitrogenas, som fixerar kvävgas ur atmosfären, och dels i de enkärniga molybdenenzymerna. De senare är enzymer som innehåller endast en molybdenatom i sina aktiva säten. De enkärniga molybdenenzymerna finns i en mängd levande system, från bakterier till växter och djur och även i människan. EnzymThe thesis deals with models for molybdopterin-dependent enzymes. Several model systems containing molybdenum or tungsten have been prepared and characterised, and their reactivity with oxygen atom acceptors and donors have been investigated. Oxygen atom transfer reactions involving oxomolybdenum bis-dithiolene complexes have been modelled using density functional calculations. The first molybden

Clinical and experimental studies in corticosteroid contact allergy

Popular Abstract in Swedish Kliniska och experimentella studier av kortisonallergi Kortisonämnen har använts sedan 1950 talets början för att behandla olika hudsjukdomar såsom eksem och psoriasis. Redan 1959 kom de första rapporterna om kontaktallergi mot hydrokortison, ett kroppseget kortisonämne. Senare studier har visat att 4–5 % av alla patienter som allergitestas med så kallat lapptest (epikuCorticosteroids are anti-inflammatory and anti-proliferative substances that also can induce sensitization, mainly through skin contact. In a sensitized individual, it can be hard to disclose the contact allergy at patch testing because the anti-inflammatory effect may mask the allergic contact reaction. This is primarily seen when patch testing to potent corticosteroids is performed and the readi

Adaptive Control (2 rev. Dover ed.)

Suitable for advanced undergraduates and graduate students, this overview introduces theoretical and practical aspects of adaptive control. It presents an excellent perspective on techniques and an active knowledge of key approaches, offering a well-developed sense of when to use adaptive techniques and when other methods are more appropriate. 1995 edition.

Investigation of image components affecting the detection of lung nodules in digital chest radiography

The aim of this work was to investigate and quantify the effects of system noise, nodule location, anatomical noise and anatomical background on the detection of lung nodules in different regions of the chest x-ray. Simulated lung nodules of diameter 10 mm but with varying detail contrast were randomly positioned in four different kinds of images: 1) clinical images collected with a 200 speed CR s

Expression of Islet Amyloid Polypeptide - Localization and regulation in the pancreatic islets, gastrointestinal tract and sensory nervous system.

Popular Abstract in Swedish Därför får man sockersjuka (Felix Mulder, 6 år): ”Det är inte bra att äta för mycket socker. Socker är vasst och skär sönder blodkropparna. Då kan man inte göra insulin och man blir sjuk.” Islet amyloid polypeptide (förkortat: IAPP) är ett medelstort äggviteämne - peptid - som upptäcktes 1986 av Per Westermark i Uppsala. Denna upptäckt har en intressant bakgrund. Det hIslet amyloid polypeptide (IAPP; also named ”amylin”) is a member of the calcitonin superfamily of peptides, displaying the closest structural relationship to the neuropeptide calcitonin gene-related peptide (CGRP). It is expressed in islet beta-cells and forms islet amyloid in type 2 diabetic patients. IAPP may restrain release and peripheral actions of insulin. Thus, IAPP has been implicated in