Objective. To investigate whether rates of cartilage loss differ in knees with frequent baseline pain versus those without pain, after adjustment for radiographic osteoarthritis (OA) stage. Methods. One knee in each of 718 Osteoarthritis Initiative participants was examined: 310 with calculated Kellgren/Lawrence (K/L) grade 2, 299 with calculated K/L grade 3, and 109 with calculated K/L grade 4. T

The assumption of wide-sense-stationarity (WSS) and uncorrelated scattering (US) of wireless propagation channels is widespread for the design and analysis of wireless propagation channels. However, the assumption is only valid within a limited range. In this paper, we investigate the extension of this range not only in time (WSS), but also in frequency (US), for measured vehicular propagation cha

Despite the huge increase in the number of management articles published during the three last decades, there is a serious shortage of high-impact research in management studies. We contend that a primary reason behind this paradoxical shortage is the near total dominance of incremental gap-spotting research in management. This domination is even more paradoxical as it is well known that gap-spott

Self-pressurization in a cylindrical ribbed tank which is partially filled with liquid hydrogen is investigated numerically under different rib spacing-to-height ratios. The Volume of Fluid (VOF) method is employed as well as a phase change model. Appropriate models are incorporated into the Ansys Fluent by the user-defined functions to carry out the computations. The ribbed surface is modeled as

To compare clinical outcomes 5 years after carpal tunnel release among patients with and without diabetes.

This study investigated three dimensions of sexual orientation-identity, attraction, and behavior-in a national survey of late adolescents. Prevalence rates and the diversity of dimensions of sexual orientation when combined were studied. A representative sample of 3,432 Swedish high school seniors completed an anonymous school-based self-report survey about sexuality, Internet use, and health. Fo

As pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are debilitating and fatal diseases it is essential to increase the understanding of patients' experience of support. The aim was to describe patients' experiences of support while living with PAH or CTEPH.

To investigate the immunomodulatory effects of β-(1,3/1,6)-d-glucan on atherosclerosis as well as on the molecular mechanisms of its transition.

We used the paradigmatic GATA-PU.1 axis to explore, at the systems level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. We combined global ChIP-seq of GATA1, GATA2, and PU.1 with expression profiling during differentiation to erythroid and neutrophil lineages. Our analysis reveals (1) differential complexity

Intrastriatal transplantation of dopamine (DA) neurons can restore DA levels in the striatum and improve parkinsonian deficits in experimental studies. However, the mechanisms underlying these effects are poorly understood. Corticostriatal synaptic plasticity represents an important cellular mechanism for information storage and behavioural learning in the brain. This mechanism is defective in Par

There are variations in quality of life (QoL) and reported risk of chronic pain after inguinal hernia repair. The aim of this study was to investigate the improvement in pain and QoL after open inguinal hernia repair, and the economic impact.

A regional variational inverse modeling system for the estimation of European biogenic CO2 fluxes is presented. This system is based on a 50 km horizontal resolution configuration of a mesoscale atmospheric transport model and on the adjoint of its tracer transport code. It exploits hourly CO2 in situ data from 15 CarboEurope-Integrated Project stations. Particular attention in the inversion setup

Paja Brava is a native South American grass with a high carbohydrate content. In the current work, the potential of us- ing this feedstock for ethanol production using a simultaneous saccharification and fermentation (SSF) process with the xylose-fermenting yeast Pichia stipitis (Scheffersomyces stipitis) CBS6054 was investigated. The straw material was subjected to SO2 catalyzed steam pretreatmen

Older people constitute an important category of eyewitnesses. Episodic memory performance in older persons is poorer than in younger adults, but little research has been made on older persons' metacognitive judgments. Since more persons of advanced age will likely be called upon as witnesses in coming years, it is critical to characterize this population's metacognitive abilities. We compared eve

There have been few attempts to synthesise the growing body of literature on phenotypic plasticity to reveal patterns and generalities about the extent and magnitude of plastic responses. Here, we conduct a review and meta-analysis of published literature on phenotypic plasticity in aquatic (marine and freshwater) gastropods, a common system for studying plasticity. We identified 96 studies, using

Adsorption of a series of charged bottle-brush polymers with side chains of different length on solid surfaces is modeled using a lattice mean-field theory. The bottle-brush polymers are modeled Lis being composed of two types of main-chain segments: charged segments and uncharged segments with ill attached side chain. The composition variable X denotes the percentage of charged main-chain segment

In this work, we present an optical approach that allows quantification of compounds dissolved down to a sub 10 ppm (molar) level in supercritical carbon dioxide (scCO(2)) by in situ Raman spectroscopy. The quantification strategy is based on the consideration of Raman signal intensity ratios and of weak Raman signals of CO2. The first measure makes the quantification strategy independent of the r