BACKGROUND: Enthesitis is one of the psoriatic arthritis (PsA) domains. Patients with enthesitis are associated with worse outcomes than those without enthesitis. The effect of secukinumab on the resolution of enthesitis in patients with PsA was explored using pooled data from the FUTURE 2 and 3 studies. METHOD: Assessments of enthesitis through week 104 used the Leeds Enthesitis Index. These post

Flyktingar, speciellt de som varit utsatta för tortyr och annan form av organiserat våld, upplever ofta en rad olika svårigheter, inklusive posttraumatiskt stressyndrom (PTSD), depression och somatiska symtom, särskilt smärta. Multidisciplinär behandling har utvecklats för att handskas med denna komorbiditet hos flyktingar, som har påvisat medelhöga effekter.Det huvudsakliga syftet med denna avhanRefugees, particularly those exposed to torture and other forms of organized violence, often experience a wide range of difficulties, including posttraumatic stress disorder (PTSD), depression, and somatic disturbances, particularly pain. Multimodal treatments have been developed to target this comorbidity in refugees, with evidence suggesting they are moderately effective.The overall aim of this

Plants respond to insect infestation with defenses targeting insect eggs on their leaves and the feeding insects. Upon perceiving cues indicating imminent herbivory, such as damage-induced leaf odors emitted by neighboring plants, they are able to prime their defenses against feeding insects. Yet it remains unknown whether plants can amplify their defenses against insect eggs by responding to cues

Pseudomonas aeruginosa efficiently adheres to human tissues, including the lungs and skin, causing infections that are difficult to treat. Laminin is a main component of the extracellular matrix, and in this study we defined bacterial laminin receptors on P. aeruginosa. Persistent clinical P. aeruginosa isolates from patients with cystic fibrosis, wounds or catheter-related urinary tract infection

Extracellular vesicle release is a wide-spread and broadly important phenomenon in bacteria. However, not much is known about the mechanism of vesicle release in Gram-positive bacteria. Observations of polarly growing Streptomyces venezuelae by live cell time-lapse imaging reveal release of extracellular membrane vesicles from tips of vegetative hyphae. Vesicle extrusion is associated with spontan

Fashions come and go. Industrialized building (IB) is no exception, having its roots far in the past and appearing in just about every type of construction, including infrastructure, at one time or another. Industrialization, as a term applied to the production of goods, can be on a macro-scale as in the case of large assemblies and near-complete structures. But it also applies to myriad products

Recent studies have revealed that areas with sediments pre-dating the Last Glacial Maximum (LGM) are more common in southern Scandinavia than previously thought. To describe and date these sediments, four deep core drillings were made in the province of Småland and one in the province of Skåne, southern Sweden, and an existing sediment core drilled in the 1960s from western Skåne was re-examined aRecent studies have revealed that areas with sediments pre-dating the Last Glacial Maximum (LGM) are more common in southern Scandinavia than previously thought. To describe and date these sediments, four deep core drillings were made in the province of Småland and one in the province of Skåne, southern Sweden, and an existing sediment core drilled in the 1960s from western Skåne was re-examined a

In 2008, the Swedish Football Association and the insurance company Folksam, where all licensed players are insured, initiated a project aiming to reduce the burden of severe knee injuries in Swedish football. As a first step, the efficacy of an injury prevention exercise programme (IPEP) was evaluated in girls’ adolescent football (12–17 years). In a large-scale cluster randomised controlled tria