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Boron neutron capture therapy for glioblastoma multiforme : Clinical studies in Sweden

A boron neutron capture therapy (BNCT) facility has been constructed at Studsvik, Sweden. It includes two filter/moderator configurations. One of the resulting neutron beams has been optimized for clinical irradiations with a filter/moderator system that allows easy variation of the neutron spectrum from the thermal to the epithermal energy range. The other beam has been designed to produce a larg

Cdc42 is involved in PKCepsilon- and delta-induced neurite outgrowth and stress fibre dismantling.

We have shown that protein kinase C (PKC)epsilon, independently of the catalytic domain, induces outgrowth of cellular processes via its regulatory domain in both neural cells and fibroblasts. This was accompanied by stress fibre loss. Here, we have examined the role of the small GTPases, Rac1, and Cdc42, in these PKC-mediated morphological and cytoskeletal changes. Both constitutively active and

Optimizing Presence–Absence Surveys For Detecting Population Trends

Presence–absence surveys are a commonly used method for monitoring broad-scale changes in wildlife distributions. However, the lack of power of these surveys for detecting population trends is problematic for their application in wildlife management. Options for improving power include increasing the sampling effort or arbitrarily relaxing the type I error rate. We present an alternative, whereby

Effect of glibenclamide on membrane response to metabolic inhibition in smooth muscle of rat portal vein

Vascular smooth muscle tone is dependent on oxidative metabolism, a phenomenon of potential importance for the metabolic regulation of blood flow to tissues. The response of the rat portal vein to inhibition of cell respiration by cyanide (0.1-1 mM) is a reduction of its spontaneous myogenic activity. The trains of action potentials triggering phasic contractions are reduced in duration, while the

Differential activation by Ca2+, ATP and caffeine of cardiac and skeletal muscle ryanodine receptors after block by Mg2+

The block of rabbit skeletal ryanodine receptors (RyR1) and dog heart RyR2 by cytosolic [Mg2+], and its reversal by agonists Ca2+, ATP and caffeine was studied in planar bilayers. Mg2+ effects were tested at submaximal activating [Ca2+] (5 microM). Approximately one third of the RyR1s had low open probability ("LA channels") in the absence of Mg2+. All other RyR1s displayed higher activity ("HA ch

An integrated analysis of ergonomics and time consumption in Swedish "craft-type' car disassembly

Car disassembly is at the edge of extensive rationalisations due to increased legislative demands for recycling. This study focused on (1) assessing Current mechanical exposures (physical work loads) for comparison with future rationalised systems, with particular emphasis on time aspects, (2) analysing disassembly work in terms of time consumption and exposures in constituent tasks as defined by

Skapa plats i landskapet : tidig- och mellanneolitiska samhällen utmed två västskånska dalgångar

Popular Abstract in SwedishDenna arkeologiska studie syftar till att förstå de neolitiska samhällenas framväxt, organisation och förändring kring de västskånska ådalgångarna vid Saxån-Välabäcken och Lödde å-Kävlingeån. Arkeologiska undersökningar och fornminnesinventeringen har visat att området hyser omfattande lämningar av neolitiska bebyggelsekomplex — i form av bosättningar, gravfält, megalitgThis dissertation deals with Early and Middle Neolithic societies in a valley landscape in western Scania, in the southern part of Sweden. Several archaeological excavations conducted by the National Heritage Board have revealed a great number of Neolithic remains in this region. The sites constitute a substantial continuous sequence from the earliest to the latest phase of the Funnel Beaker Cultu

Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats.

OBJECTIVES:We investigated if changes in serum/plasma fibrinogen (FIB), hyaluronan (HA) and cartilage oligomeric matrix protein (COMP) levels can be used to differentiate between inflammation and cartilage involvement during arthritis. METHODS:Collagen-induced arthritis (CIA), oil-induced arthritis (OIA) and for comparison, experimental autoimmune encephalitis (EAE) induced in DA rats were investi

Review of Oloph Bexell, Präster i S:t Sigfrids stift 3. Minnesteckningar till prästmötet i Växjö stift 2002. Lund 2002

Bexell tecknar minnet av 78 präster. Omfattande forskningsinsatser ligger bakom den 29 sidor långa biografin över domprosten Gustaf Adolf Danell, som utreder frågan varför Danell, som uppfördes på åtta biskopsförslag, aldrig utnämndes. Ärkebiskop Brilioth sökte redan 1956 aktivt avvärja utnämning av Danell, som kritiserat biskoparnas ämbetsförvaltning och saknade kompromissförmåga. Bexell förenar

Morphology, structure, and electronic properties of Ce@C-82 films on Ag : Si(111)-(root 3x root 3)R30 degrees

The adsorption behaviour and electronic properties of Ce@C-82 molecules on the Ag: Si(l I I)-(root3 x root3)R30degrees surface have been studied using scanning tunnelling microscopy and photoelectron spectroscopy. Submonolayer coverages and multilayer films of Ce@C-82 comprise highly ordered molecular domains which have a single, well-defined orientation with respect to the underlying substrate cr