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Rare and low-frequency coding variants alter human adult height

Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per allele (such as those in IHH, STC2, AR and CRISPLD2), greater than ten times the a

Valuing nature's contributions to people : the IPBES approach

Nature is perceived and valued in starkly different and often conflicting ways. This paper presents the rationale for the inclusive valuation of nature's contributions to people (NCP) in decision making, as well as broad methodological steps for doing so. While developed within the context of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES), this approach is more widel

On the Evolution of the Determinants of Household Poverty in Mexico : a Logistic Regression Analysis

Mexico, the second largest economy in Latin America, has almost eradicated extreme poverty according to the Millennium Development Goals; however, official statistics show that by national standards poverty levels are still quite high, reaching up to half its population. This paper looks into how the determinants of poverty in Mexico have evolved after the last major economic crisis the country ex

An analytical method for calculating the thermal conductivity of a twin pipe in district heating system

In this paper a simple analytical method is introduced for calculating the overall thermal conductivity of a twin pipe in district heating network. The method is developed based on calculating the conductive and convective heat transfer around the casing pipe in different perimetral sections. Temperature inside the supply and return pipes and also over the heating pipe is measured on different poi

Introduktion - Fyra aktuella frågor. Språket, aktivismen, korruptionen och "splittringen"

10TAL nr 17/18 Ukraina är en unik intro­duk­tion till sam­tida ukrainsk lit­te­ra­tur, konst och kul­tur­de­batt. Vi pre­sen­te­rar 25 ukrainska för­fat­tare, över­sät­tare och konst­nä­rer, som alla på ett eller annat sätt för­hål­ler sig till kri­get, inva­sio­nen och lit­te­ra­tu­rens roll i dagens Ukraina. 10TALs num­mer är det första någon­sin som helt foku­se­rar på Ukrainas sam­tida lit­te­