The defense against mucosal infections relies on chemokines that recruit inflammatory cells to the mucosa. This study examined if the chemokine response to uro-pathogenic Escherichia coli is influenced by fimbrial expression. The CXC (CXCL1, CXCL5, CXCL8, CXCL9, CXCL10) and CC chemokines (CCL2, CCL3, CCL5) were quantified after in vitro infection of uro-epithelial cells with a fimbriated E. coli p

Popular Abstract in Swedish Från 1980-talet har etiken diskuterats flitigt i samhället. Det har i samband med detta utvecklats etiska kommittéer. Etiska kommittéer är en typ av organ inom företag, branscher, professioner och andra organisationer som handhar etiska frågor och problem. De etiska kommittéerna fungerar rådgivande i etiska frågor, de kan fastställa etiska regler för en organisation ochThis thesis analyses the development of ethics committees from a sociology of law perspective and a social steerage perspective ("social control"). The main question is: Why are ethics committees established? Institutionalised ethics committee is a rather new phenomenon, which has become widely spread in the last 20 years. The study points out the public ethical debate since the 1980s as a major e

This paper is concerned with a new class of graded algebras naturally uniting within a single framework various deformations of the Witt, Virasoro and other Lie algebras based on twisted and deformed derivations, as well as color Lie algebras and Lie superalgebras.

Popular Abstract in Swedish Den sedimentära lagerföljd som bygger upp Gotland avlagrades för drygt 400 miljoner år sedan (under silurperioden) i ett varmt tropiskt innanhav strax söder om ekvatorn. Innanhavet sträckte sig som en vid bukt in över dagens södra Skandinavien, Baltikum och vidare mot sydost, till Ukraina. Avhandlingen behandlar primärt hur sedimentationsmönster utvecklades under cirka The Silurian foreland of Scandinavia included a vast epicontinental carbonate platform system of which the island of Gotland (Sweden) is an erosional remnant. This thesis treats the Late Wenlock succession (Cyrtograptus lundgreni, Pristiograptus dubius parvus, Gothograptus nassa, Colonograptus(?) praedeubeli, and the Co(?) deubeli zones), and emphasises the sedimentology and biostratigraphy of the

Spiders were collected, mostly by pitfall trapping in the 1970s, in a variety of habitats, mainly in lowland areas all around Iceland. Among the 62 species collected five were first records for Iceland (viz. Micaria pulicaria, Robertus lyrifer, Theonoe minutissima, Wabasso replicatus, and Bathyphantes gracilis). Most of the material (comprising ca 18 000 adult spiders) was obtained by pitfall trap

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Abstract in Undetermined Kardiovaskulära sjukdomar med debut i yngre åldrar är ofta ärftliga. Molekylärgenetisk diagnostik kan förbättra möjligheten till presymtomatisk diagnostik i drabbade familjer. Förbättrad presymtomatisk diagnostik kan rikta förebyggande sjukvårdsåtgärder mot dem som har högst risk att insjukna, och kan därmed vara kostnadseffektiv.

High spin states in the nucleus Tc-91 have been studied via the fusion evaporation reaction Ni-58(Ar-36,3p)Tc-91, at 149 MeV and 140 MeV beam energy. The OSWS spectrometer, an additional high purity Ge detector at 162 degrees, and several particle detectors were used to measure gamma gamma- and particle-gamma coincidences, directional correlations of oriented states, and line shapes due to Doppler

The title compound, [ RhCl( PBz(3))(2)( CO)] [ PBz(3) = tribenzylphosphine, P(C7H7)(3)], which is the first reported tribenzylphosphine - rhodium( I) structure, has pseudo- square- planar coordination geometry, with Rh - P bond distances of 2.3164 ( 15) and 2.3156 ( 16) Angstrom. The Rh - Cl, Rh - C and C - O bond distances are 2.3654 ( 15), 1.783 ( 6) and 1.162 ( 6) Angstrom, respectively, and th

High spin states in Y-81 UP to the probable 33/2(+) and 29/2(-) yrast states have been measured via the reaction Ni-58(Si-28, alpha p), using the Cologne tandem accelerator. Directional correlations of oriented nuclei were determined and the level scheme was extended with lifetimes measured by means of DSA and recoil distance techniques. Reduced transition strengths inferred from lifetimes were co

The influence of different types of surfactants on ultrafiltration membranes has been investigated. A basic approach to membrane-surfactant interactions is also presented. A nonionic (Triton X-100), two anionic (potassium oleate and sodium dodecylbenzenesulphonate) and a cationic (hexadecyltrimethylammonium bromide) surfactant were investigated. The effects on commercial membranes of polysulphone,

Breast cancer is a rare disease in men, affecting less than 0.1% of the male population. Two heritable gene defects have been associated with a predisposition to male breast cancer development, ie., germ-line mutations in the breast cancer susceptibility gene BRCA2 and the androgen receptor (AR) gene. In this study, the entire coding regions of BRCA2 and AR were screened for mutations in 34 consec

Background: The immunosuppressive effects of thiopurine drugs are mainly mediated through their intracellular metabolism into active 6-thioguanine nucleotide (6-TGN) metabolites, which are incorporated into DNA. Erythrocyte 6-TGN (E-6TGN) levels have been proposed as an instrument for monitoring treatment. The aim of the study was to use erythrocyte E-6TGN, methylated mercaptopurine (MeMP) metabol

PURPOSE. To compare intersubject variability and normal limits of threshold values between the new Swedish interactive test algorithm short wavelength automated perimetry (SITA SWAP) and the older Full Threshold SWAP programs (Carl Zeiss Meditec, Dublin, CA). METHODS. Normal reduction of differential tight sensitivity with age, age-corrected thresholds, intersubject variability, and normal limits