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Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells

Objectives: Tumor-associated-trypsin inhibitor (TATI) is frequently coexpressed with trypsinogen in tumors. Recently, we found expression of trypsinogens in prostate cancer. We have now studied whether TATI is also expressed in prostate cancer and if TATI expression is associated with Gleason grade, proliferation, and neuroendocrine differentiation. Methods: Expression of TATI and prostate-specifi

Functional limits of empirical distributions in crossing theory

We present a functional limit theorem for the empirical level-crossing behaviour of a stationary Gaussian process. This leads to the well-known Slepian model process for a Gaussian process after an upcrossing of a prescribed level as a weak limit in C-space for an empirically defined finite set of functions.We also stress the importance of choosing a suitable topology by giving some natural exampl

Astrophysical lasers operating in optical Fe II lines in stellar ejecta of η Carinae

After the discovery of space masers based on OH radicals (Weaver et al.cite{Wea65}) and H2O (Cheung et al. cite{Che69}) such microwavelasers have been found to work in more than 100 molecular species(Elitzur cite{Eli92}; Townes cite{Tow97}), as well as in highlyexcited H atoms (Strelnitski et al. cite{Str96}). In the IR region (10mum), the effect of stimulated emission of radiation in the CO2molec

Regulatory effects of aerosolized budesonide and adrenalectomy on the lung content of endothelin-1 in the rat

This study was designed to investigate the effect of inflammation and glucocorticosteroids (GCS) on the content of endothelin-1-like immunoreactivity (ET-LI) in the rat lung. Following intratracheal instillation of Sephadex beads, which induces a long-lasting inflammation in the lung, there was an increase in the lung content of ET-LI measured by RIA. This increase was abolished by locally adminis

High-resolution electron spectroscopy of different adsorption states of ethylene on Pd(111)

The adsorption of ethylene at 100 K on clean and oxygen precovered Pd(1 1 1) surfaces and the thermal evolution of the ethylene adsorbate layers have been investigated experimentally by high-resolution electron energy loss spectroscopy (HREELS), high-resolution X-ray photoelectron spectroscopy with synchrotron radiation, thermal desorption spectroscopy and theoretically by ab initio density functi

Differential exoprotease activities confer tumor-specific serum peptidome patterns

Recent studies have established distinctive serum polypeptide patterns through mass spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider acceptance of these signatures as valid biomarkers for disease may follow sequence characterization of the components and elucidation of the mechanisms by which they are generated. Using a highly optimized peptide extraction and ma

Effects of postural disturbances with fatigued triceps surae muscles or with 20% additional body weight

One of the main issues for balance control is the ability to generate enough forces to execute motions and uphold stability. This study aimed to investigate whether induced fatigue of the triceps surae muscles and decreased muscle force due to temporary additional body weight affected the ability to withstand balance perturbations. Another aim was to examine whether postural control adaptation ove

Preoperative grading of glioma malignancy with thallium-201 single-photon emission CT: comparison with conventional CT

PURPOSE: To compare thallium-201 single-photon emission CT with conventional CT in grading the malignancy of gliomas and to determine the reliability of each in tumor assessment. METHODS: We studied 37 patients who had gliomas (31 high grade and 6 low grade) and compared the CT findings with the thallium-201 index, which we defined as tumor uptake relative to the uptake in the contralateral hemisp

Hormonemate, a new cytotoxic and apoptosis-inducing compound from the endophytic fungus Hormonema dematioides. I. Identification of the producing strain, and isolation and biological properties of hormonemate

In a search for new fungal compounds inducing apoptosis of the colon cancer derived cell line COLO-320, hormonemate (1) was purified from fermentations of an endophytic fungus isolated from living needles of a Pinus species. The producing strain was identified as Hormonema dematioides by microscopy and ITS rDNA sequence analysis. The structure of hormonemate was determined by spectroscopic methods

Evaluation of long-term mating disruption of Ephestia kuehniella and Plodia interpunctella (Lepidoptera: Pyralidae) in indoor storage facilities by pheromone traps and monitoring of relative aerial concentrations of pheromones

The potential for pheromone-based mating disruption (MD) of Ephestia kuehniella (Walker) and Plodia interpunctella (Hübner) (Lepidoptera: Pyralidae) was investigated in two flour mills and a pet food distributor. Plastic sachets emitting 2–3 mg per d ( Z, E)-9,12-tetradecadienyl acetate, the major pheromone component of both moth species, were used as MD dispensers, which were applied in grid syst

Temperament and character in adults with Asperger syndrome

To study the personality characteristics of adults with Asperger syndrome, and investigate the value of self-rating personality inventories, we administered the Temperament and Character Inventory (TCI) to 31 outpatients with Asperger syndrome.The TCI is a self-rating personality inventory that has been validated in the Swedish general population. The results were compared with age- and sex-matche

The inverse scattering problem for a homogeneous bi-isotropic slab using transient data

Transient wave propagation in a finite bi-isotropic slab is treated. The incident field impinges normally on the slab, which can be inhomogeneous wrt depth. Dispersion and bi-isotropy are modeled by time convolutions in the constitutive relations. Outside the slab the medium is assumed to be homogeneous, non-dispersive and isotropic, and such that there is no phase velocity mismatch at the boundar

Soil properties affecting the frost sensitivity of beech bark in southern Sweden

Decline in pH and leakage of base cations have been recorded in beech forest soils in southern Sweden. This study investigated the influence of soil properties on frost sensitivity in beech bark and evaluated the effects on frost sensitivity of soil treatment with lime, wood ash or excessive N fertilization. Beech trees on five experimental sites were studied. The results indicated that beech tree

Short-term BOD (BODst) as a parameter for on-line monitoring of biological treatment process Part 1. A novel design of BOD biosensor for easy renewal of bio-receptor

A novel design of a biochemical oxygen demand (BOD) biosensor has been developed for on-line monitoring of easily biodegradable organic compounds in aqueous samples. The biological recognition element of the sensor could be easily renewed by injecting new bacterial paste without disassembling the sensor system. The sensor measurements were carried out in the initial-rate mode using a flow injectio

'The strength of strong ties': University spin-offs and the significance of historical relations

This article investigates the relationship between universities and academic spin-offs, with special emphasis on the antecedent conditions of, and the nature of the linkages that the spin-offs form, as well as the means for sustaining them. The present research uses an instrumental case study approach, and is also an instance of a collective case study as four companies of various size and activit